Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sarcoma, Ewing/genetics"'
Publikováno v:
The New England journal of medicine, vol. 384, no. 2, pp. 154-164
In 1920, during a meeting of the New York Pathological Society, James Ewing described an unusual tumor in a 14-year-old girl as a “diffuse endothelioma of bone.”1 The tumor had initially been diagnosed as an osteosarcoma, but its architecture, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::4cf691af0fa211b0aa9a69856c713324
https://serval.unil.ch/resource/serval:BIB_D9FCD24578B0.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_D9FCD24578B0.P001/REF.pdf
Autor:
Ivan Stamenkovic, Miguel Rivera, Angela Volorio, Sowmya Iyer, Liliane C. Broye, Nicolo Riggi, Gaylor Boulay
Publikováno v:
Genes & development, vol. 32, no. 15-16, pp. 1008-1019
Various types of repetitive sequences are dysregulated in cancer. In Ewing sarcoma, the oncogenic fusion protein EWS-FLI1 induces chromatin features typical of active enhancers at GGAA microsatellite repeats, but the function of these sites has not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5970a5a72d1ba8518ad231ed454cdb0
https://pubmed.ncbi.nlm.nih.gov/30068701
https://pubmed.ncbi.nlm.nih.gov/30068701
Autor:
Nicolo Riggi, Anoop P. Patel, Martin J. Aryee, Vishal Thapar, Gaylor Boulay, Aurélie Formey, G. Petur Nielsen, Ivan Stamenkovic, Shawn M. Gillespie, Edward B. Cook, Nikki E. Rossetti, Melissa Gymrek, Mario L. Suvà, Birgit Knoechel, David T. Ting, Francis J. Hornicek, Bradley E. Bernstein, Esther Rheinbay, Vikram Deshpande, Wannaporn E. Boonseng, Ozgur Oksuz, Miguel Rivera
Publikováno v:
Cancer cell, vol. 26, no. 5, pp. 668-681
SummaryThe aberrant transcription factor EWS-FLI1 drives Ewing sarcoma, but its molecular function is not completely understood. We find that EWS-FLI1 reprograms gene regulatory circuits in Ewing sarcoma by directly inducing or repressing enhancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27644e8c251df925d6e8729c03419ab
https://europepmc.org/articles/PMC4492343/
https://europepmc.org/articles/PMC4492343/
Autor:
Ovidiu Radulescu, Bernard Delyon, Olivier Delattre, Tatiana Baumuratova, Anne Siegel, Didier Surdez, Gautier Stoll
Publikováno v:
BMC Systems Biology
BMC Systems Biology, 2010, 4 (1), pp.146. ⟨10.1186/1752-0509-4-146⟩
BMC Systems Biology, BioMed Central, 2010, 4 (1), pp.146. 〈10.1186/1752-0509-4-146〉
BMC Systems Biology, BioMed Central, 2010, 4 (1), pp.146. ⟨10.1186/1752-0509-4-146⟩
BMC Systems Biology, 4, 146. England (2010).
BMC Systems Biology, Vol 4, Iss 1, p 146 (2010)
BMC Systems Biology, 2010, 4 (1), pp.146. ⟨10.1186/1752-0509-4-146⟩
BMC Systems Biology, BioMed Central, 2010, 4 (1), pp.146. 〈10.1186/1752-0509-4-146〉
BMC Systems Biology, BioMed Central, 2010, 4 (1), pp.146. ⟨10.1186/1752-0509-4-146⟩
BMC Systems Biology, 4, 146. England (2010).
BMC Systems Biology, Vol 4, Iss 1, p 146 (2010)
Background A wide range of techniques is now available for analyzing regulatory networks. Nonetheless, most of these techniques fail to interpret large-scale transcriptional data at the post-translational level. Results We address the question of usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9beb7d7e6cb99cd6ec86dd2aec4812ee
https://www.hal.inserm.fr/inserm-00984711
https://www.hal.inserm.fr/inserm-00984711
Autor:
Philippe Terrier, Marie José Terrier-Lacombe, Louis Guillou, Gabrielle Gallagher, Jean Benhattar, Dominique Ranchère, Jean-Michel Coindre, Frédéric Chibon
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, vol. 22, no. 1, pp. 87-94
Superficial primitive Ewing's sarcomas are rare and have been reported to be of favorable prognosis compared to conventional deep-seated tumors. In the skin and subcutis, the diagnosis is often difficult, and performing molecular cytogenetic techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15c7770cc8bcd4b274281a3d024ab9c
https://serval.unil.ch/notice/serval:BIB_1DAD8475273F
https://serval.unil.ch/notice/serval:BIB_1DAD8475273F
Autor:
Domizio Suva, Luisa Cironi, Paolo Provero, Ivan Stamenkovic, Jean-Christophe Stehle, Stéphane Tercier, Vincent Kindler, Mario-Luca Suvà, Jean-Marc Joseph, Nicolo Riggi, Karine Baumer
Publikováno v:
Cancer Research, Vol. 68, No 7 (2008) pp. 2176-2185
Ewing's sarcoma family tumors (ESFT) express the EWS-FLI-1 fusion gene generated by the chromosomal translocation t(11;22)(q24;q12). Expression of the EWS-FLI-1 fusion protein in a permissive cellular environment is believed to play a key role in ESF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d09e026b6aae5330ea9ef1b2e5f80ce
https://pubmed.ncbi.nlm.nih.gov/18381423
https://pubmed.ncbi.nlm.nih.gov/18381423