Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Saray López-Benito"'
Autor:
Alena Salašová, Niels Sanderhoff Degn, Mikhail Paveliev, Niels Kjærgaard Madsen, Saray López Benito, Plinio Casarotto, Peter Lund Ovesen, Benedicte Vestergaard, Andreea Cornelia Udrea, Lilian Kisiswa, Lucie Woloszczuková, Islam Faress, Sadegh Nabavi, Eero Castrén, Juan Carlos Arévalo, Mai Marie Holm, Mads Fuglsang Kjølby, Ulrik Bølcho, Anders Nykjaer
BackgroundHuntington’s disease (HD) is a fatal neurodegenerative disorder characterized by progressive motor dysfunction and loss of medium spiny neurons (MSNs) in dorsal striatum. Brain-derived neurotrophic factor (BDNF) sustains functionality and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8773065dbf200d9bfabb28e28fce1a
https://doi.org/10.1101/2021.11.03.466767
https://doi.org/10.1101/2021.11.03.466767
Autor:
Nuria Suelves, Albert Giralt, Verónica Brito, Andrés Miguez, Saray López-Benito, Juan Carlos Arévalo, Gerardo García-Díaz Barriga, Jordi Alberch, Silvia Ginés, Elena Alvarez-Periel
Publikováno v:
Molecular Neurobiology. 56:935-953
Deficits in striatal brain-derived neurotrophic factor (BDNF) delivery and/or BDNF/tropomyosin receptor kinase B (TrkB) signaling may contribute to neurotrophic support reduction and selective early degeneration of striatal medium spiny neurons in Hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fffcb3502f120b32fd1bc581b25f3c7
https://doi.org/10.1007/s12035-018-1126-5
https://doi.org/10.1007/s12035-018-1126-5
Autor:
Carlos Martín-Rodríguez, Cristina Vicente-García, Saray López-Benito, Begoña Anta, Laura Calvo, Juan Carlos Arévalo, Carolina Gomis-Perez, Andrés Ángel Calderón-García, Alvaro Villarroel
Publikováno v:
Journal of Biological Chemistry. 291:19132-19145
Ubiquitination of the TrkA neurotrophin receptor in response to NGF is critical in the regulation of TrkA activation and functions. TrkA is ubiquitinated, among other E3 ubiquitin ligases, by Nedd4-2. To understand mechanistically how TrkA ubiquitina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615e1deec14d67f99a10c6466236c5f2
https://doi.org/10.1074/jbc.m116.722637
https://doi.org/10.1074/jbc.m116.722637
Autor:
Ada Jimenez-Gonzalez, Raquel E. Rodríguez, Juan Carlos Arévalo, Veronica Gonzalez-Nunez, Adrián García-Concejo, Saray López-Benito
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1860:1308-1316
Background Morphine is one of the first-line therapies for the treatment of pain despite its secondary effects. It modifies the expression of epigenetic factors like miRNAs. In the present study, we analyzed miR-212 and miR-132 and their implication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e3093389b0b2d8bb9bf02fc4a57b93
https://doi.org/10.1016/j.bbagen.2016.03.001
https://doi.org/10.1016/j.bbagen.2016.03.001
Autor:
Nuria, Suelves, Andrés, Miguez, Saray, López-Benito, Gerardo García-Díaz, Barriga, Albert, Giralt, Elena, Alvarez-Periel, Juan Carlos, Arévalo, Jordi, Alberch, Silvia, Ginés, Verónica, Brito
Publikováno v:
Molecular neurobiology. 56(2)
Deficits in striatal brain-derived neurotrophic factor (BDNF) delivery and/or BDNF/tropomyosin receptor kinase B (TrkB) signaling may contribute to neurotrophic support reduction and selective early degeneration of striatal medium spiny neurons in Hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24fc1453e926a8c5d2000d10c13ce44d
https://pubmed.ncbi.nlm.nih.gov/29804232
https://pubmed.ncbi.nlm.nih.gov/29804232
Autor:
Dionisio Martin-Zanca, Juan Carlos Arevalo, Pilar Pérez, Francis S. Lee, Begoña Anta, Saray López-Benito, Carlos Martín-Rodríguez, Laura Calvo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The development of the nervous system is a temporally and spatially coordinated process that relies on the proper regulation of the genes involved. Neurotrophins and their receptors are directly responsible for the survival and differentiation of sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711b14c0c80627e612450a5bf2e7b0dd
https://doi.org/10.1523/jneurosci.4646-14.2015
https://doi.org/10.1523/jneurosci.4646-14.2015
Autor:
Begoña Anta, Saray López-Benito, Moses V. Chao, Eileen Southon, Laura Calvo, Tao Yu, Juan Carlos Arévalo, Lino Tessarollo
Publikováno v:
Traffic. 12:521-534
Upon activation by nerve growth factor (NGF), TrkA is internalized, trafficked and sorted through different endosomal compartments. Proper TrkA trafficking and sorting are crucial events as alteration of these processes hinders NGF-mediated functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310e2b69d6117e45ade85bc69ecfab97
https://doi.org/10.1111/j.1600-0854.2010.01156.x
https://doi.org/10.1111/j.1600-0854.2010.01156.x
Autor:
Angel Hernández-Hernández, Moses V. Chao, Concepción Lillo, Saray López-Benito, Juan Carlos Arévalo
Publikováno v:
Journal of cell science. 129(9)
Proper development of the nervous system requires a temporally and spatially orchestrated set of events including differentiation, synapse formation and neurotransmission. NGF acting through the TrkA neurotrophin receptor regulates many of these even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd60b1024139a32cd33e9bfa9287fb8
https://pubmed.ncbi.nlm.nih.gov/26966186
https://pubmed.ncbi.nlm.nih.gov/26966186
Autor:
Juan Carlos Arévalo, Antonio E. Paniagua, Concepción Lillo, Ángela M. Jimeno, José Aijón, Saray López-Benito, Saúl Herranz-Martín, David Jimeno, Almudena Velasco
Publikováno v:
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The CRB proteins CRB1, CRB2 and CRB3 are members of the cell polarity complex Crumbs in mammals that together with Scribble and Par complexes stablish the polarity of a variety of cell types. Although many members of the Crumbs complex proteins are e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c155e3cc0df155a92473b369c3a42026
https://pubmed.ncbi.nlm.nih.gov/26404741
https://pubmed.ncbi.nlm.nih.gov/26404741