Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Saravanan Prabhu Nadarajan"'
Autor:
Haosheng Shen, Changyu Zhang, Shengjie Li, Yuanmei Liang, Li Ting Lee, Nikhil Aggarwal, Kwok Soon Wun, Jing Liu, Saravanan Prabhu Nadarajan, Cheng Weng, Hua Ling, Joshua K. Tay, De Yun Wang, Shao Q. Yao, In Young Hwang, Yung Seng Lee, Matthew Wook Chang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Prodrugs have been explored as an alternative to conventional chemotherapy; however, their target specificity remains limited. The tumor microenvironment harbors a range of microorganisms that potentially serve as tumor-targeting vectors for
Externí odkaz:
https://doaj.org/article/1c2ab6bf7c8c40ffa2f1fe969fdd164f
Autor:
Gazi Sakir Hossain, Saravanan Prabhu Nadarajan, Lei Zhang, Tee-Kheang Ng, Jee Loon Foo, Hua Ling, Won Jae Choi, Matthew Wook Chang
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Living organisms have evolved over millions of years to fine tune their metabolism to create efficient pathways for producing metabolites necessary for their survival. Advancement in the field of synthetic biology has enabled the exploitation of thes
Externí odkaz:
https://doaj.org/article/39540e8587734a76a9226f9613d0f5b6
Autor:
Saravanan Prabhu, Nadarajan, Ayyadurai, Niraikulam, Deepankumar, Kanagavel, Chung, Taeowan, Lim, Dong Joon, Yun, Hyungdon
Publikováno v:
In Journal of Molecular Catalysis. B, Enzymatic June 2012 78:57-64
Autor:
Dillon T. Flood, Amol D. Pagar, Hyungdon Yun, Saravanan Prabhu Nadarajan, Hyunwoo Jeon, Mahesh D. Patil, Philip E. Dawson, Yumi Won
Publikováno v:
Chemical Communications. 55:15133-15136
Herein we report the development of an efficient cellular system for the in vivo biosynthesis of Tyr-analogs and their concurrent incorporation into target proteins by the residue-specific approach. This system makes use of common phenol derivatives
Autor:
Gyeong Tae Eom, Murali Kannan Maruthamuthu, Saravanan Prabhu Nadarajan, Vidhya Selvamani, Soon Ho Hong, You-Kwan Oh, Hyungdon Yun
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 45:31-41
In a cell-surface display (CSD) system, successful display of a protein or peptide is highly dependent on the anchoring motif and the position of the display in that anchoring motif. In this study, a recombinant bacterial CSD system for manganese (Mn
Publikováno v:
Biotechnology and Bioprocess Engineering. 22:504-511
In the past decade, numerous studies have been reported that the residue specific incorporation of fluorine containing analogs into protein can enhance the stability of protein. On the other hand, the incorporation of fluoroproline can enhance both s
Publikováno v:
Enzyme and Microbial Technology. :52-60
An (S)-ω-transaminase from the thermophilic eubacterium Sphaerobacter thermophilus was expressed and functionally characterized. The enzyme showed good stability at high temperature and in the presence of various substrates. Substrate specificity an
Publikováno v:
Applied Biological Chemistry. 59:173-179
Hydroxycinnamates are a class of phenolic compounds that have a C6-C3 carbon backbone. Hydroxycinnamic acids are derived from cinnamic acid via hydroxylation or methylation and are found in foods such as pears, coffee beans, and dandelions. They are
Publikováno v:
Biotechnology Journal. 10:1862-1876
The bioprocess engineering with biocatalysts broadly spans its development and actual application of enzymes in an industrial context. Recently, both the use of bioprocess engineering and the development and employment of enzyme engineering technique
Autor:
Kanagavel Deepankumar, Hyungdon Yun, Saravanan Prabhu Nadarajan, Dong-Ho Bae, Kwang-Hyun Baek, Kwon-Young Choi
Publikováno v:
Biotechnology and Bioprocess Engineering
Genetically encoded fluorescent proteins are extensively utilized for labeling and imaging proteins, organelles, cell tissues, and whole organisms. In this study, we explored the feasibility of mRFP1 and its variants for measuring intracellular tempe