Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Saravanan Gunaseelan"'
Autor:
Saravanan Gunaseelan, Mohammed Zacky Ariffin, Sanjay Khanna, Mong How Ooi, David Perera, Justin Jang Hann Chu, John Jia En Chua
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Neurological complications are frequently observed in severe Hand, Foot and Mouth Disease but the underlying causes are unknown. Here, the authors report infected astrocytes release CXCL1 which activates neuronal CXCR2 to cause neuropathogenesis.
Externí odkaz:
https://doaj.org/article/bb651a6c1d6244838851cecd5c408c1c
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 6, Pp 1165-1171 (2022)
The human brain contains an estimated 100 billion neurons that must be systematically organized into functional neural circuits for it to function properly. These circuits range from short-range local signaling networks between neighboring neurons to
Externí odkaz:
https://doaj.org/article/ff187ed575b24280a73ef6f6a62b3a80
Autor:
Saravanan Gunaseelan, Mohammed Zacky Ariffin, Sanjay Khanna, Mong How Ooi, David Perera, Justin Jang Hann Chu, John Jia En Chua
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/5e015a8c38f34ef4b4c082bb4ee4f865
Autor:
Saravanan Gunaseelan, Mohammed Zacky Ariffin, Sanjay Khanna, Mong How Ooi, David Perera, Justin Jang Hann Chu, John Jia En Chua
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f599ff4c3a294306af564c38ca5550a8
Autor:
Oleksandr Yagensky, Mahdokht Kohansal-Nodehi, Saravanan Gunaseelan, Tamara Rabe, Saima Zafar, Inga Zerr, Wolfgang Härtig, Henning Urlaub, John JE Chua
Publikováno v:
eLife, Vol 8 (2019)
Alzheimer’s disease is the most prevalent neurodegenerative disorder leading to progressive cognitive decline. Despite decades of research, understanding AD progression at the molecular level, especially at its early stages, remains elusive. Here,
Externí odkaz:
https://doaj.org/article/4cbe94fcbad84bdfab292bab1304059f
Autor:
Venetia Kok Jing Tong, Sylvester Wong Shu Ming, Kah-Leong Lim, Ziyin Wang, Rafhanah Banu Bte Abdul Razar, Saravanan Gunaseelan, Sumitra Srimasorn, Wei-Yi Ong, John Jia En Chua
Publikováno v:
Human Molecular Genetics. 30:5-20
FEZ1-mediated axonal transport plays important roles in central nervous system development but its involvement in the peripheral nervous system is not well-characterized. FEZ1 is deleted in Jacobsen syndrome (JS), an 11q terminal deletion development
Autor:
Saravanan, Gunaseelan, Mohammed Zacky, Ariffin, Sanjay, Khanna, Mong How, Ooi, David, Perera, Justin Jang Hann, Chu, John Jia En, Chua
Publikováno v:
Nature communications. 13(1)
Hand, foot and mouth disease (HFMD) caused by Human Enterovirus A71 (HEVA71) infection is typically a benign infection. However, in minority of cases, children can develop severe neuropathology that culminate in fatality. Approximately 36.9% of HEVA7
Publikováno v:
Future Virology. 12:171-191
Human enterovirus 71 (HEV71) has been considered as an essential human pathogen, which causes hand, foot and mouth disease in young children. Several HEV71 outbreaks have been observed in many Asia-Pacific countries for the past two decades with sign
Autor:
Kai Zhi Wong, Nyo Min, Nur Khairiah Binte Mohd Ismail, Yee-Joo Tan, Regina Ching Hua Lee, Saravanan Gunaseelan, Justin Jang Hann Chu, Jialei Sun
Publikováno v:
Science Translational Medicine. 11
Human enterovirus A71 (HEVA71) causes hand, foot, and mouth disease (HFMD) in young children and is considered a major neurotropic pathogen but lacks effective antivirals. To identify potential therapeutic agents against HFMD, we screened a 502-compo
Autor:
Saravanan Gunaseelan, Mahdokht Kohansal-Nodehi, Saima Zafar, John Jia En Chua, Wolfgang Härtig, Inga Zerr, Henning Urlaub, Oleksandr Yagensky, Tamara Rabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48592339ac7b2d340331508815573f7f
https://doi.org/10.7554/elife.47498.031
https://doi.org/10.7554/elife.47498.031