Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Saravanan, Thangamani"'
Autor:
Ikechukwu B. Jacob, Amanda Gemmiti, Weichuan Xiong, Erin Reynolds, Brian Nicholas, Saravanan Thangamani, Hongpeng Jia, Guirong Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSARS coronavirus 2 (SARS-CoV-2) infects human angiotensin-converting enzyme 2 (hACE2)-expressing lung epithelial cells through its spike (S) protein. The S protein is highly glycosylated and could be a target for lectins. Surfactant prote
Externí odkaz:
https://doaj.org/article/64a2bb928cd844d0ac49d07dda507a5c
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Heartland virus was first isolated in 2009 from two patients in Missouri and is transmitted by the Lone Star tick, Amblyomma americanum. To understand disease transmission and pathogenesis, it is necessary to develop an animal model which ut
Externí odkaz:
https://doaj.org/article/4bb6680eb67740f29dd51c737b0fcbf0
Autor:
Erin S. Reynolds, Charles E. Hart, Jacob T. Nelson, Brandon J. Marzullo, Allen T. Esterly, Dakota N. Paine, Jessica Crooker, Paul T. Massa, Saravanan Thangamani
Publikováno v:
Viruses, Vol 16, Iss 6, p 820 (2024)
Tick-borne flaviviruses (TBFV) can cause severe neuroinvasive disease which may result in death or long-term neurological deficit in over 50% of survivors. Multiple mechanisms for invasion of the central nervous system (CNS) by flaviviruses have been
Externí odkaz:
https://doaj.org/article/f5073f2bd0724a41bce39f5cdf2d1ee9
Autor:
Allison Li, John F. Lindo, Hilary Beckles, James L. Mohler, Marvin Reid, Michael Boyne, Jack DeHovitz, Patricia I. Diaz, Paul Brown, Joshua Anzinger, Christine Carrington, Kathryn B. Anderson, Alan Landay, Michael Cummings, Elizabeth Chernyak, Gina Prescott, Raymond Cha, Saravanan Thangamani, Ernest Barthelemy, Steven Dubovsky, Ative Ennis, Tracy Evans-Gilbert, Gene D. Morse
Publikováno v:
Frontiers in Education, Vol 8 (2023)
The State University of New York (SUNY) – University of the West Indies (UWI) Health Research Consortium (HRC) was implemented in 2015 by the SUNY Global Health Institute (GHI) and the SUNY-UWI Center for Leadership and Sustainable Development. The
Externí odkaz:
https://doaj.org/article/5c77416992b84b65a184866d26c34832
Autor:
Charles Hart, Laura A. Schad, Jahnavi Reddy Bhaskar, Erin S. Reynolds, Christopher P. Morley, Saravanan Thangamani
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Ticks transmit several arthropod-borne pathogens in New York State. The primary human-biting ticks in this region are Ixodes scapularis, Amblyomma americanum, and Dermacentor variabilis. Body regions where tick bites human vary depending on
Externí odkaz:
https://doaj.org/article/ec97cf205d814122aad9c983fdd2299f
Autor:
Tetsuro Ikegami, Eduardo Jurado-Cobena, Cigdem Alkan, Jennifer K. Smith, Lihong Zhang, Birte Kalveram, Terry L. Juelich, Allen T. Esterly, Jahnavi R. Bhaskar, Saravanan Thangamani, Alexander N. Freiberg
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Rift Valley fever (RVF) is a mosquito-borne zoonosis endemic to Africa and the Arabian Peninsula, which causes large outbreaks among humans and ruminants. Single dose vaccinations using live-attenuated RVF virus (RVFV) support effective prev
Externí odkaz:
https://doaj.org/article/4e41bca749494ed99684009ae280a8e8
Autor:
Charles Hart, Erin Hassett, Chantal B.F. Vogels, Daniel Shapley, Nathan D. Grubaugh, Saravanan Thangamani
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 2, Pp 415-417 (2023)
Powassan virus is a tickborne flavivirus that can cause lethal or debilitating neurologic illness. It is canonically transmitted by Ixodes spp. ticks but might spill over to sympatric Dermacentor species. We detected Powassan virus lineage I from a p
Externí odkaz:
https://doaj.org/article/75cd3785b1db471e9ff44595bf1d354a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Powassan virus (POWV) is a neuroinvasive flavivirus transmitted to mammals by the bite of ixodid ticks. In this study, we sought to investigate the impact of tick salivary gland extract (SGE) on POWV neuroinvasion. BALB/c mice were footpad i
Externí odkaz:
https://doaj.org/article/af51e77a1f204ae9989dbb27e95d90ae
Autor:
Allen T. Esterly, Megan G. Lloyd, Prashant Upadhyaya, Jennifer F. Moffat, Saravanan Thangamani
Publikováno v:
JID Innovations, Vol 2, Iss 4, Pp 100128- (2022)
Arboviruses such as flaviviruses and alphaviruses cause a significant human healthcare burden on a global scale. Transmission of these viruses occurs during human blood feeding at the mosquito-skin interface. Not only do pathogen immune evasion strat
Externí odkaz:
https://doaj.org/article/7bd5edacb2ca4a719bb77341165c777d
Autor:
Awadalkareem Adam, Huanle Luo, Samantha R. Osman, Binbin Wang, Christopher M. Roundy, Albert J. Auguste, Kenneth S. Plante, Bi-Hung Peng, Saravanan Thangamani, Elena I. Frolova, Ilya Frolov, Scott C. Weaver, Tian Wang
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 305-316 (2021)
A chimeric Eilat/ Chikungunya virus (EILV/CHIKV) was previously reported to replicate only in mosquito cells but capable of inducing robust adaptive immunity in animals. Here, we initially selected C7/10 cells to optimize the production of the chimer
Externí odkaz:
https://doaj.org/article/f3f548d1b633474499e9cf3d257987ab