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pro vyhledávání: '"Sarath P. D. Seenadera"'
Autor:
Sarath P. D. Seenadera, Sarah A. Long, Rhone Akee, Gabriela Bermudez, Gregory Parsonage, Jonathan Strope, Cody Peer, W. Douglas Figg, Kathlyn A. Parker, David J. Beech, John A. Beutler
Publikováno v:
ACS medicinal chemistry letters. 13(9)
Modifications at the glycolate moiety of englerin A were made to explore variations at the most sensitive site on the molecule for activity in the NCI 60 screen, wherein englerin A is highly potent and selective for renal cancer cells. Replacement of