Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Sarath Chandra Janga"'
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-15 (2024)
ABSTRACT2´-O-methylation (Nm) is one of the most abundant modifications found in both mRNAs and noncoding RNAs. It contributes to many biological processes, such as the normal functioning of tRNA, the protection of mRNA against degradation by the d
Externí odkaz:
https://doaj.org/article/b4116d68eda54be283e2902fcc05a789
Autor:
Sheikh Firdous Ahmad, Celus Chandrababu Shailaja, Sakshi Vaishnav, Amit Kumar, Gyanendra Kumar Gaur, Sarath Chandra Janga, Syed Mudasir Ahmad, Waseem Akram Malla, Triveni Dutt
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Elucidating genome-wide structural variants including copy number variations (CNVs) have gained increased significance in recent times owing to their contribution to genetic diversity and association with important pathophysiologi
Externí odkaz:
https://doaj.org/article/675617b66c6f4efe92b8f8658ea41afa
Autor:
Qinyu Hao, Minxue Liu, Swapna Vidhur Daulatabad, Saba Gaffari, You Jin Song, Rajneesh Srivastava, Shivang Bhaskar, Anurupa Moitra, Hazel Mangan, Elizabeth Tseng, Rachel B Gilmore, Susan M Frier, Xin Chen, Chengliang Wang, Sui Huang, Stormy Chamberlain, Hong Jin, Jonas Korlach, Brian McStay, Saurabh Sinha, Sarath Chandra Janga, Supriya G Prasanth, Kannanganattu V Prasanth
Publikováno v:
eLife, Vol 13 (2024)
Out of the several hundred copies of rRNA genes arranged in the nucleolar organizing regions (NOR) of the five human acrocentric chromosomes, ~50% remain transcriptionally inactive. NOR-associated sequences and epigenetic modifications contribute to
Externí odkaz:
https://doaj.org/article/125bf24a87b9450d9f1f38fca36d642a
Autor:
Alexander Krohannon, Mansi Srivastava, Simone Rauch, Rajneesh Srivastava, Bryan C. Dickinson, Sarath Chandra Janga
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Recent discovery of the gene editing system - CRISPR (Clustered Regularly Interspersed Short Palindromic Repeats) associated proteins (Cas), has resulted in its widespread use for improved understanding of a variety of biological
Externí odkaz:
https://doaj.org/article/481167256dcb47cc85b673944de6d728
Autor:
Cassandra Catacalos, Alexander Krohannon, Sahiti Somalraju, Kate D Meyer, Sarath Chandra Janga, Kausik Chakrabarti
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12, p e1010972 (2022)
"Epitranscriptomics" is the new RNA code that represents an ensemble of posttranscriptional RNA chemical modifications, which can precisely coordinate gene expression and biological processes. There are several RNA base modifications, such as N6-meth
Externí odkaz:
https://doaj.org/article/a37756c3a40345f0902866631a78261b
Autor:
Doaa Hassan, Hunter Mathias Gill, Michael Happe, Ashay D. Bhatwadekar, Amir R. Hajrasouliha, Sarath Chandra Janga
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Diabetic retinopathy (DR) is a late microvascular complication of Diabetes Mellitus (DM) that could lead to permanent blindness in patients, without early detection. Although adequate management of DM via regular eye examination can preserve vision i
Externí odkaz:
https://doaj.org/article/16163981429942d09a3102bf10437251
Autor:
Ratanond Koonchanok, Swapna Vidhur Daulatabad, Quoseena Mir, Khairi Reda, Sarath Chandra Janga
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Direct-sequencing technologies, such as Oxford Nanopore’s, are delivering long RNA reads with great efficacy and convenience. These technologies afford an ability to detect post-transcriptional modifications at a single-molecule
Externí odkaz:
https://doaj.org/article/ccf5b24fb45842adbc4c395d8f59aa0a
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Background With advancements in omics technologies, the range of biological processes where long non-coding RNAs (lncRNAs) are involved, is expanding extensively, thereby generating the need to develop lncRNA annotation resources. Although,
Externí odkaz:
https://doaj.org/article/2bd349f678fd4600b5f6668739743e9c
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Interaction between proteins and RNA is critical for post-transcriptional regulatory processes. Existing high throughput methods based on crosslinking of the protein–RNA complexes and poly-A pull down are reported to contribute to biases a
Externí odkaz:
https://doaj.org/article/e005abf55b5f4c2183e62b75a48df238
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0260331 (2022)
SARS-CoV-2 has affected people worldwide as the causative agent of COVID-19. The virus is related to the highly lethal SARS-CoV-1 responsible for the 2002-2003 SARS outbreak in Asia. Research is ongoing to understand why both viruses have different s
Externí odkaz:
https://doaj.org/article/211ce3da95004f24a8c3e88018be3ebc