Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Saratchandra Singh Khumukcham"'
Autor:
Alyssa Mauri Cornista, Maria Virginia Giolito, Kristi Baker, Hajar Hazime, Inès Dufait, Jashodeep Datta, Saratchandra Singh Khumukcham, Mark De Ridder, Jatin Roper, Maria T. Abreu, Karine Breckpot, Kevin Van der Jeught
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 8, Pp 1103-1119 (2023)
Cancer immunotherapy has become an indispensable mode of treatment for a multitude of solid tumor cancers. Colorectal cancer (CRC) has been one of the many cancer types to benefit from immunotherapy, especially in advanced disease where standard trea
Externí odkaz:
https://doaj.org/article/7a853b37793742bdb339c632a4618df9
Autor:
Srikanth Battu, Sumbul Afroz, Jeevan Giddaluru, Saima Naz, Weishan Huang, Saratchandra Singh Khumukcham, Rafiq Ahmad Khan, Saleem Yousuf Bhat, Insaf Ahmed Qureshi, Bramanandam Manavathi, Aleem Ahmed Khan, Avery August, Seyed Ehtesham Hasnain, Nooruddin Khan
Publikováno v:
PLoS Biology, Vol 16, Iss 4, p e2005317 (2018)
Activation of the amino acid starvation response (AAR) increases lifespan and acute stress resistance as well as regulates inflammation. However, the underlying mechanisms remain unclear. Here, we show that activation of AAR pharmacologically by Halo
Externí odkaz:
https://doaj.org/article/4475e910e3734fa4a2d29e1cbe9801cb
Autor:
Saratchandra Singh Khumukcham, Anita Soni, Chiranjeevi Padala, Vasudevarao Penugurti, Bramanandam Manavathi, Abdul Salam Pk, Mohit Kumar Jolly, Kishore Hari, Srinivasulu Mukta, Triveni B, Anju Dwivedi, Veena Uppala
Publikováno v:
Cancer Letters. 526:12-28
While phenotypic plasticity is a critical factor contributing to tumor heterogeneity, molecular mechanisms underlying this process are largely unknown. Here we report that breast cancer cells display phenotypic diversity in response to hypoxia or nor
Autor:
Chiranjeevi Padala, Bramanandam Manavathi, Anju Dwivedi, Aprotim Mazumder, Vincent Goffin, Sinjini Ghosh, Vasudevarao Penugurti, Saratchandra Singh Khumukcham, Anita Kumari
Publikováno v:
The FEBS Journal. 289:1575-1590
Hematopoietic PBX-interacting protein (HPIP, also known as PBXIP1) is an estrogen receptor (ER) interacting protein that regulates estrogen-mediated breast cancer cell proliferation and tumorigenesis. However, its functional significance in the conte
Publikováno v:
RSC Advances. 10:24095-24107
Among the breast cancers, triple negative breast cancer (TNBC) has relatively poor outcomes with a lower survival rate and personalised chemotherapy is the only option available for treatment. Currently in the biomedical domain, nanomaterials with po
Autor:
Anju Dwivedi, Saratchandra Singh Khumukcham, Chiranjeevi Padala, Aprotim Mazumder, Sinjini Ghosh, Vasudevarao Penugurti, Vincent Goffin, Bramanandam Manavathi, Anita Kumari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea671ec2baf463bc18995c8fd6f21ed
https://doi.org/10.1111/febs.16242/v3/response1
https://doi.org/10.1111/febs.16242/v3/response1
Autor:
Triveni Bhopal, Chiranjeevi Padala, Srinivasulu Mukta, Anju Dwivedi, Karthik Reddy Kamireddy, Vasudevarao Penugurti, Bramanandam Manavathi, Saratchandra Singh Khumukcham
Publikováno v:
Cancer letters. 518
While cancer cells rewire metabolic pathways to sustain growth and survival under metabolic stress in solid tumors, the molecular mechanisms underlying these processes remain largely unknown. In this study, cancer cells switched from survival to deat
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1876(1)
Hematopoietic PBX interacting protein (HPIP or pre-B-cell leukemia transcription factor interacting protein (PBXIP1) was discovered two decades ago as a corepressor of pre-B-cell leukemia homeobox (PBX) 1 with a vital functional role in hematopoiesis
Autor:
Bramanandam Manavathi, Loka Reddy Velatooru, Sivareddy Kotla, Vasudevarao Penugurti, Anita Kumari, Saratchandra Singh Khumukcham, P S Kesavan, Venkata Subrahmanyam Kumar Samanthapudi, Aprotim Mazumder
Publikováno v:
J Biol Chem
Proper cell division relies on the coordinated regulation between a structural component, the mitotic spindle, and a regulatory component, anaphase-promoting complex/cyclosome (APC/C). Hematopoietic PBX-interacting protein (HPIP) is a microtubule-ass
Publikováno v:
RSC advances. 10(40)
Among the breast cancers, triple negative breast cancer (TNBC) has relatively poor outcomes with a lower survival rate and personalised chemotherapy is the only option available for treatment. Currently in the biomedical domain, nanomaterials with po