Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Saralili Dipa Robertson"'
Publikováno v:
Frontiers in Microbiology, Vol 5 (2015)
Rheumatoid arthritis (RA) is an autoimmune disease characterised by inflammation, tissue rebuilding and fibrosis. Inability by the body to regulate inflammation effectively is one of the hallmarks of RA. Interactions between the external environment
Externí odkaz:
https://doaj.org/article/d2a23f317b2644758e4c98fb9aa7b92b
Autor:
Saralili Dipa Robertson, Monika Hermansson, Jonathan S Jones, Robin Wait, Philip Mitchell, Nidhi Sofat
Publikováno v:
Rheumatology International
Cartilage destruction is a hallmark of osteoarthritis (OA) and is characterized by increased protease activity resulting in the degradation of critical extracellular matrix (ECM) proteins essential for maintaining cartilage integrity. Tenascin-C (TN-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50955539003f1d6e7273f6f81828bec1
https://openaccess.sgul.ac.uk/id/eprint/101662/1/296_2011_Article_2067.pdf
https://openaccess.sgul.ac.uk/id/eprint/101662/1/296_2011_Article_2067.pdf
Publikováno v:
Journal of Innate Immunity
Cartilage loss is a feature of chronic arthritis. It results from degradation of the extracellular matrix which is composed predominantly of aggrecan and type II collagen. Extracellular matrix degradation is mediated by aggrecanases and matrix metall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7845bfd7b1da3f94978d9f6e01b3e39d
https://pubmed.ncbi.nlm.nih.gov/21997473
https://pubmed.ncbi.nlm.nih.gov/21997473
Publikováno v:
The Journal of Biological Chemistry
Ca(2+)/calmodulin-dependent protein kinase II (alphaCaMKII) is thought to exert its role in memory formation by autonomous Ca(2+)-independent persistent activity conferred by Thr(286) autophosphorylation, allowing the enzyme to remain active even whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f83478b4a6c916cc588de484d38e93
https://pubmed.ncbi.nlm.nih.gov/19654320
https://pubmed.ncbi.nlm.nih.gov/19654320