Monkeypox virus genomic accordion strategies

Autor: Sara Monzón, Sarai Varona, Anabel Negredo, Santiago Vidal-Freire, Juan Angel Patiño-Galindo, Natalia Ferressini-Gerpe, Angel Zaballos, Eva Orviz, Oskar Ayerdi, Ana Muñoz-Gómez, Alberto Delgado-Iribarren, Vicente Estrada, Cristina García, Francisca Molero, Patricia Sánchez-Mora, Montserrat Torres, Ana Vázquez, Juan-Carlos Galán, Ignacio Torres, Manuel Causse del Río, Laura Merino-Diaz, Marcos López, Alicia Galar, Laura Cardeñoso, Almudena Gutiérrez, Cristina Loras, Isabel Escribano, Marta E. Alvarez-Argüelles, Leticia del Río, María Simón, María Angeles Meléndez, Juan Camacho, Laura Herrero, Pilar Jiménez, María Luisa Navarro-Rico, Isabel Jado, Elaina Giannetti, Jens H. Kuhn, Mariano Sanchez-Lockhart, Nicholas Di Paola, Jeffrey R. Kugelman, Susana Guerra, Adolfo García-Sastre, Isabel Cuesta, Maripaz P. Sánchez-Seco, Gustavo Palacios

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Abstract The 2023 monkeypox (mpox) epidemic was caused by a subclade IIb descendant of a monkeypox virus (MPXV) lineage traced back to Nigeria in 1971. Person-to-person transmission appears higher than for clade I or subclade IIa MPXV, possibly cause

Externí odkaz: https://doaj.org/article/b702225a6b8044b886dd81bd6742679e

Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes

Autor: Violeta Lara-Aguilar, Cristina Rueda, Irene García-Barbazán, Sarai Varona, Sara Monzón, Pilar Jiménez, Isabel Cuesta, Ángel Zaballos, Óscar Zaragoza

Publikováno v: Virulence, Vol 12, Iss 1, Pp 1400-1417 (2021)

Candida auris has emerged as a fungal pathogen that causes nosocomial outbreaks worldwide. Diseases caused by this fungus are of concern, due to its reduced susceptibility to several antifungals. C. auris exhibits paradoxical growth (PG; defined as g

Externí odkaz: https://doaj.org/article/b9fd96d77fda452abf282dce64e3cccc

Emergence of Progressive Mutations in SARS-CoV-2 From a Hematologic Patient With Prolonged Viral Replication

Autor: Carolina Garcia-Vidal, María Iglesias-Caballero, Pedro Puerta-Alcalde, Vicente Mas, Genoveva Cuesta-Chasco, Nicole Garcia-Pouton, Sarai Varona, Francisco Pozo, Sonia Vázquez-Morón, Maria Angeles Marcos, Alex Soriano, Inmaculada Casas, HEMATOCOVID19-Researchers Group

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

We documented a hematologic patient with prolonged SARS-CoV-2 viral replication in whom emergence of viral mutations was documented after the consecutive use of antivirals and convalescent plasma. The virus detected in the last of 12 clinical samples

Externí odkaz: https://doaj.org/article/024e23b7dbc149a1be57d435421add81

Differences in Expression of IQSEC2 Transcript Isoforms in Male and Female Cases with Loss of Function Variants and Neurodevelopmental Disorder

Autor: Beatriz Baladron, Lidia M. Mielu, Estrella López-Martín, Maria J. Barrero, Lidia Lopez, Jose I. Alvarado, Sara Monzón, Sarai Varona, Isabel Cuesta, Rosario Cazorla, Julián Lara, Gemma Iglesias, Enriqueta Román, Purificación Ros, Gema Gomez-Mariano, Isabel Cubillo, Esther Hernandez-San Miguel, Daniel Rivera, Javier Alonso, Eva Bermejo-Sánchez, Manuel Posada, Beatriz Martínez-Delgado

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 16, p 9480 (2022)

Pathogenic hemizygous or heterozygous mutations in the IQSEC2 gene cause X-linked intellectual developmental disorder-1 (XLID1), characterized by a variable phenotype including developmental delay, intellectual disability, epilepsy, hypotonia, autism

Externí odkaz: https://doaj.org/article/3fadb91b6f934808bc67226a1363f5f2

Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes

Autor: Ángel Zaballos, Violeta Lara-Aguilar, Oscar Zaragoza, Sara Monzón, Cristina Rueda, Sarai Varona, Irene García-Barbazán, Pilar Jiménez, Isabel Cuesta

Publikováno v: Virulence
article-version (VoR) Version of Record
Virulence, Vol 12, Iss 1, Pp 1400-1417 (2021)
Repisalud
Instituto de Salud Carlos III (ISCIII)

Candida auris has emerged as a fungal pathogen that causes nosocomial outbreaks worldwide. Diseases caused by this fungus are of concern, due to its reduced susceptibility to several antifungals. C. auris exhibits paradoxical growth (PG; defined as g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b5d3e27d940497cf4a8d55e9cb091f
http://europepmc.org/articles/PMC8244764