Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sarai H, Stuart"'
Autor:
Lin Xu, Joshua L. Pierce, Angelica Sanchez, Kenneth S. Chen, Abhay A. Shukla, Nicholas J. Fustino, Sarai H. Stuart, Aditya Bagrodia, Xue Xiao, Lei Guo, Mark D. Krailo, Furqan Shaikh, Deborah F. Billmire, Farzana Pashankar, Jessica Bestrashniy, J. Wolter Oosterhuis, Ad J. M. Gillis, Yang Xie, Lisa Teot, Jaume Mora, Jenny N. Poynter, Dinesh Rakheja, Leendert H. J. Looijenga, Bruce W. Draper, A. Lindsay Frazier, James F. Amatruda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Germ cell tumors (GCTs) are neoplasms of the testis, ovary and extragonadal sites that occur in infants, children, adolescents and adults. Post-pubertal (type II) malignant GCTs may present as seminoma, non-seminoma or mixed histologies. In
Externí odkaz:
https://doaj.org/article/7de0ec00eddb4344af90c7a9512816da
Autor:
James F. Amatruda, Dinesh Rakheja, Theodore W. Laetsch, Leendert H.J. Looijenga, Lawrence Lum, A. Lindsay Frazier, Payal Kapur, Kiyoshi Yamaguchi, Sarai H. Stuart, Christina Ateek, Albert Budhipramono, Emily K. Stroup, Abhay A. Shukla, Nicholas J. Fustino, Kenneth S. Chen
Germ cell tumors (GCT) are malignant tumors that arise from pluripotent embryonic germ cells and occur in children and young adults. GCTs are treated with cisplatin-based regimens which, while overall effective, fail to cure all patients and cause si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d02f346e8bfa5d168d6fbe51a99d23af
https://doi.org/10.1158/1535-7163.c.6538071.v1
https://doi.org/10.1158/1535-7163.c.6538071.v1
Autor:
Sarai H. Stuart, Veena Rajaram, Kenneth S. Chen, James F. Amatruda, Emily K. Stroup, Gordan M. Vujanic, Tamra Slone, Dinesh Rakheja, Abhay S. Shukla, Jason Wang
Publikováno v:
JCO Precision Oncology. :1-9
DICER1 syndrome1 predisposes to a variety of cancers, including pleuropulmonary blastoma (PPB),2 ovarian Sertoli-Leydig cell tumor (SLCT),3 embryonal rhabdomyosarcoma,4 and kidney tumors.5–8 In DICER1 syndrome, most patients bear a germline null mu
Autor:
Kenneth S, Chen, Sarai H, Stuart, Emily K, Stroup, Abhay S, Shukla, Jason, Wang, Veena, Rajaram, Gordan M, Vujanic, Tamra, Slone, Dinesh, Rakheja, James F, Amatruda
Publikováno v:
JCO precision oncology. 2
Autor:
Claudette Fraire, Abhay A. Shukla, Lin Xu, James F. Amatruda, Sarai H. Stuart, Albert Budhipramono, Kenneth S. Chen, Diana X. Nichols-Vinueza, Emily K. Stroup, Joshua T. Mendell, Dinesh Rakheja
Publikováno v:
Genes & Development. 32:996-1007
Many childhood Wilms tumors are driven by mutations in the microRNA biogenesis machinery, but the mechanism by which these mutations drive tumorigenesis is unknown. Here we show that the transcription factor pleomorphic adenoma gene 1 (PLAG1) is a mi
Autor:
Dinesh Rakheja, Theodore W. Laetsch, Leendert H. J. Looijenga, Emily K. Stroup, Lawrence G. Lum, James F. Amatruda, Abhay A. Shukla, Payal Kapur, Kiyoshi Yamaguchi, A. Lindsay Frazier, Nicholas Fustino, Sarai H. Stuart, Christina S. Ateek, Albert Budhipramono, Kenneth S. Chen
Publikováno v:
Molecular Cancer Therapeutics, 17(5), 1079-1089. American Association for Cancer Research Inc.
Germ cell tumors (GCT) are malignant tumors that arise from pluripotent embryonic germ cells and occur in children and young adults. GCTs are treated with cisplatin-based regimens which, while overall effective, fail to cure all patients and cause si
Autor:
L. Teot, Jessica Bestrashniy, Aditya Bagrodia, Dinesh Rakheja, L.H.J. Looijenga, Lauren Xu, J. Mora, J. Stoop, A. Lindsay Frazier, Katharina Biermann, F. Pashankar, James F. Amatruda, Mark Krailo, Jen Poynter, J. Wolter Oosterhuis, J. L. Pierce, A. J. M. Gillis, Sarai H. Stuart, B.W. Draper, Kenneth S. Chen, Yang Xie, Abhay A. Shukla, Deborah F. Billmire, Nicholas Fustino, Furqan Shaikh, A. Sanchez
Publikováno v:
Nature communications, vol 14, iss 1
EUR UROL SUPPL
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
EUR UROL SUPPL
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Germ cell tumors (GCTs) are neoplasms of the testis, ovary and extragonadal sites that occur in infants, children, adolescents and adults. Post-pubertal (type II) malignant GCTs may present as seminoma, non-seminoma or mixed histologies. In contrast,
Autor:
Dinesh Rakheja, Richard L. Boriack, Theodore W. Laetsch, James F. Amatruda, Julia C. Meade, Agnieszka Cholka, David A. Boothman, Jingying Xu, Sarai H. Stuart, Anat Erdreich-Epstein, Zachary R. Moore
Publikováno v:
Cancer Research. 76:B39-B39
Atypical Teratoid/ Rhabdoid Tumor (ATRT) is an aggressive cancer that accounts for up to 20% of infant brain tumors. Even with intense chemotherapy and radiation, approximately 75% of children die from their disease at a median of 10 months after dia
Autor:
David A. Boothman, Sarai H. Stuart, Ashwin Venkataraman, Theodore W. Laetsch, James F. Amatruda, Agnieszka Cholka, Anat Erdreich-Epstein, Dinesh Rakheja, Jingying Xu, Zachary R. Moore
Publikováno v:
Cancer Research. 75:1613-1613
Atypical teratoid rhabdoid tumors (ATRTs) are aggressive malignant neoplasms that occur in the CNS, most commonly in children 15 uM). A two-hour pulse with ß-lap caused a burst of ROS-mediated DNA damage and PARP1 hyperactivation, resulting in NAD+