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pro vyhledávání: '"Sarah Zippusch"'
Autor:
Sarah Zippusch, Axel Haverich, Mathias Wilhelmi, Ulrike Böer, Skadi Lau, Melanie Klingenberg, Thomas Aper, Florian Helms
Publikováno v:
Annals of Biomedical Engineering. 49:2066-2079
The generation of cellularized bioartificial blood vessels resembling all three layers of the natural vessel wall with physiological morphology and cell alignment is a long pursued goal in vascular tissue engineering. Simultaneous culture of all thre
Autor:
Florian Helms, Sarah Zippusch, Thomas Aper, Stefan Kalies, Alexander Heisterkamp, Axel Haverich, Ulrike Böer, Mathias Wilhelmi
Publikováno v:
Tissue engineering. Part A. 28(19-20)
Generation of bioartificial blood vessels with a physiological three-layered wall architecture is a long pursued goal in vascular tissue engineering. While considerable advances have been made to resemble the physiologicalitunica intima/iandimedia/im
Autor:
Florian Helms, Sarah Zippusch, Jonathan Theilen, Axel Haverich, Mathias Wilhelmi, Ulrike Böer
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(8)
Facilitating sufficient nutrient and oxygen supply in large-scale bioartificial constructs is a critical step in organ bioengineering. Immediate perfusion not only depends on a dense capillary network, but also requires integrated large-diameter vess
Autor:
Axel Haverich, Florian Helms, Peter Behrens, Melanie Klingenberg, Mathias Wilhelmi, Nina Ehlert, Anne Lyons, Karen F W Besecke, Sarah Zippusch, Ulrike Böer
Publikováno v:
Regenerative Biomaterials
Inadequate vascularization leading to insufficient oxygen and nutrient supply in deeper layers of bioartificial tissues remains a limitation in current tissue engineering approaches to which pre-vascularization offers a promising solution. Hypoxia tr
Autor:
Axel Haverich, Sarah Zippusch, Florian Helms, Ulrike Böer, Melanie Klingenberg, Mathias Wilhelmi, Claudia Schrimpf, Skadi Lau
Publikováno v:
The International journal of artificial organs. 44(2)
Vascularization of tissue engineered implants is crucial for their survival and integration in the recipient’s body. Pre-vascularized, fibrin-based implants offer a solution since low concentration fibrin hydrogels (1 mg/mL) have been shown to prom