Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sarah Zerimech"'
Publikováno v:
Frontiers in Molecular Medicine, Vol 3 (2023)
Multiple sclerosis (MS) is a chronic demyelinating disease with prominent axon dysfunction. Our previous studies in an MS mouse model, experimental autoimmune encephalomyelitis (EAE), demonstrated that major histocompatibility complex Class II constr
Externí odkaz:
https://doaj.org/article/7609ac041ad14bdba87ea7527e71be99
Autor:
Chinthasagar Bastian, Sarah Zerimech, Hung Nguyen, Christine Doherty, Caroline Franke, Anna Faris, John Quinn, Selva Baltan
Publikováno v:
Experimental neurology. 357
The astrocyte-neuron lactate shuttle (ANLS) is an essential metabolic support system that uptakes glucose, stores it as glycogen in astrocytes, and provides glycogen-derived lactate for axonal function. Aging intrinsically increases the vulnerability
Autor:
Mathieu Desroches, Martin Krupa, Paolo Scalmani, Alexandre Loucif, Sandrine Cestèle, Lara Pizzamiglio, Louisiane Lemaire, Massimo Mantegazza, Isabelle Léna, Sarah Zerimech, Fabrice Duprat, Marion Ayrault, Oana Chever
Publikováno v:
The Journal of clinical investigation
The Journal of clinical investigation, 2021, 131 (21), ⟨10.1172/JCI142203⟩
The Journal of clinical investigation, 2021, 131 (21), pp.e142203. ⟨10.1172/JCI142203⟩
The Journal of Clinical Investigation
The Journal of clinical investigation, 2021, 131 (21), ⟨10.1172/JCI142203⟩
The Journal of clinical investigation, 2021, 131 (21), pp.e142203. ⟨10.1172/JCI142203⟩
The Journal of Clinical Investigation
International audience; Spreading depolarizations (SDs) are involved in migraine, epilepsy, stroke, traumatic brain injury, and subarachnoid hemorrhage. However, the cellular origin and specific differential mechanisms are not clear. Increased glutam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bfb93071dd5e127c1f4b08d57caefd8
https://hal.archives-ouvertes.fr/hal-03411366/document
https://hal.archives-ouvertes.fr/hal-03411366/document
Publikováno v:
Neurochem Res
This review summarizes the diverse structure and function of astrocytes to describe the bioenergetic versatility required of astrocytes that are situated at different locations. The intercellular domain of astrocyte mitochondria defines their roles i
Autor:
Marion Ayrault, Martin Krupa, Alexandre J.C. Loucif, Sarah Zerimech, Sandrine Cestèle, Massimo Mantegazza, Paolo Scalmani, Louisiane Lemaire, Mathieu Desroches, Oana Chever, Fabrice Duprat
Cortical spreading depression (CSD) is a pathologic mechanism of migraine. We have identified a novel neocortex-specific mechanism of CSD initiation and a novel pathological role of GABAergic neurons. Mutations of the NaV1.1 sodium channel (the SCN1A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f0367b8aa4895d208d74708af28e9e
Autor:
Fabrice Duprat, Lara Pizzamiglio, Oana Chever, Massimo Mantegazza, Sarah Zerimech, Paolo Scalmani
Publikováno v:
Neuropharmacology
Neuropharmacology, Elsevier, 2020, 166, pp.107951. ⟨10.1016/j.neuropharm.2020.107951⟩
Neuropharmacology, Elsevier, 2020, 166, pp.107951. ⟨10.1016/j.neuropharm.2020.107951⟩
International audience; Cortical spreading depression (CSD) is a wave of transient network hyperexcitability leading to long lasting depolarization and block of firing, which initiates focally and slowly propagates in the cerebral cortex. It causes m