Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sarah Y. Branch"'
Autor:
Eva Troyano-Rodriguez, Harris E. Blankenship, Kylie Handa, Sarah Y. Branch, Michael J. Beckstead
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Substantia nigra pars compacta (SNc) dopamine neurons are required for voluntary movement and reward learning, and advanced age is associated with motor and cognitive decline. In the midbrain, D2-type dopamine receptors located at dendrodend
Externí odkaz:
https://doaj.org/article/3fabb43524e64ee8a7708752402415af
Substantia nigra pars compacta (SNc) dopamine neurons are required for voluntary movement and reward learning, and advanced age is associated with motor and cognitive decline. In the midbrain, D2-type autoreceptors located on dendrodendritic synapses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee0e3f615237d4e62b0b38b360aee196
https://doi.org/10.1101/2022.07.10.498507
https://doi.org/10.1101/2022.07.10.498507
Autor:
Cang Chen, Sarah Y. Branch, Amanda L. Sharpe, Senlin Li, Michael J. Beckstead, William B. Lynch, Guo Ge, Christopher W. Tschumi
Publikováno v:
Movement Disorders. 33:1928-1937
Background Parkinson's disease is characterized by the progressive loss of dopamine neurons in the substantia nigra, leading to severe motor deficits. Although the disease likely begins to develop years before observable motor symptoms, the specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f68c601246c260a01a3f47b08f8e3400
https://doi.org/10.1002/mds.27541
https://doi.org/10.1002/mds.27541
Autor:
Michael J. Beckstead, Stewart A. Anderson, Jennifer J. Donegan, Sarah Y. Branch, Daniel J. Lodge, Jennifer A. Tyson
Publikováno v:
Molecular psychiatry
An increasing literature suggests that schizophrenia is associated with a reduction in hippocampal interneuron function. Thus, we posit that stem cell-derived interneuron transplants may be an effective therapeutic strategy to reduce hippocampal hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39e52fd69534a4e76ef45318d97d548
http://europepmc.org/articles/PMC5290293
http://europepmc.org/articles/PMC5290293
Autor:
Nicholas A. Courtney, Michael J. Beckstead, Sarah Y. Branch, Christopher P. Ford, Elisabeth Piccart
Publikováno v:
Journal of Neuroscience. 35:11144-11152
Increased dopaminergic signaling is a hallmark of severe mesencephalic pathologies such as schizophrenia and psychostimulant abuse. Activity of midbrain dopaminergic neurons is under strict control of inhibitory D2 autoreceptors. Application of the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9dbf3281461db8c01b89399ececbf48
https://doi.org/10.1523/jneurosci.3816-14.2015
https://doi.org/10.1523/jneurosci.3816-14.2015
Publikováno v:
Journal of Neuroscience. 34:9310-9318
Substantia nigra dopamine neurons are involved in behavioral processes that include cognition, reward learning, and voluntary movement. Selective deterioration of these neurons is responsible for the motor deficits associated with Parkinson's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d1d1f71e2dfc50e3c175b3fa070583
https://doi.org/10.1523/jneurosci.4228-13.2014
https://doi.org/10.1523/jneurosci.4228-13.2014
Autor:
Sarah Y. Branch, Michael J. Beckstead
Publikováno v:
Journal of Neurophysiology. 108:802-809
Amphetamine-like compounds are commonly used to enhance cognition and to treat attention deficit/hyperactivity disorder, but they also function as positive reinforcers and are self-administered at doses far exceeding clinical relevance. Many of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fdd90a0dfce7e3d047d17f77d962f5
https://doi.org/10.1152/jn.00094.2012
https://doi.org/10.1152/jn.00094.2012
Autor:
Sarah Y. Branch, James D. Lechleiter, Cang Chen, Ramaswamy Sharma, Michael J. Beckstead, Senlin Li
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(14)
Dopaminergic neurons of the substantia nigra (SN) play a vital role in everyday tasks, such as reward-related behavior and voluntary movement, and excessive loss of these neurons is a primary hallmark of Parkinson's disease (PD). Mitochondrial dysfun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3292025092cb8158763f576ab2c6d734
https://pubmed.ncbi.nlm.nih.gov/27053209
https://pubmed.ncbi.nlm.nih.gov/27053209
Autor:
Sarah Y. Branch, Stewart A. Anderson, Daniel J. Lodge, Jennifer A. Tyson, Michael J. Beckstead, Jennifer J. Donegan
Publikováno v:
Molecular Psychiatry. 22:1369-1369
Stem cell-derived interneuron transplants functionally integrate within the existing circuitry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a49dcfe5651c5cc3b6eafa0cbee093de
https://doi.org/10.1038/mp.2017.198
https://doi.org/10.1038/mp.2017.198
Autor:
R. Brandon Goertz, Janie Pierce, Sarah Y. Branch, Amanda L. Sharpe, Sudip Roy, Daijin Ko, Carlos A. Paladini, Michael J. Beckstead
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(34)
Restriction of food intake increases the acquisition of drug abuse behavior and enhances the reinforcing efficacy of those drugs. However, the neurophysiological mechanisms responsible for the interactions between feeding state and drug use are large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1812000ca2017d8e8a0b8c490194139f
https://pubmed.ncbi.nlm.nih.gov/23966705
https://pubmed.ncbi.nlm.nih.gov/23966705