Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Sarah Williams-Blangero"'
Autor:
Vincent P. Diego, Eron G. Manusov, Xi Mao, Marcio Almeida, Juan M. Peralta, Joanne E. Curran, Michael C. Mahaney, Harald Göring, John Blangero, Sarah Williams-Blangero
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background: Socioeconomic Status (SES) is a potent environmental determinant of health. To our knowledge, no assessment of genotype-environment interaction has been conducted to consider the joint effects of socioeconomic status and genetics on risk
Externí odkaz:
https://doaj.org/article/37f1a4f6dab94266a5fe3f973d126ef2
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundFrailty is characterized by an accumulation of deficits that lead to vulnerability to adverse health outcomes. The Frailty Index (FI) quantifies frailty by measuring deficits that increase susceptibility to stressors. This study focused on
Externí odkaz:
https://doaj.org/article/4cadf09505414148a55dcfd7401563db
Autor:
Vincent P. Diego, Eron G. Manusov, Marcio Almeida, Sandra Laston, David Ortiz, John Blangero, Sarah Williams-Blangero
Publikováno v:
Genes, Vol 15, Iss 5, p 547 (2024)
Statistical genetic models of genotype-by-environment (G×E) interaction can be divided into two general classes, one on G×E interaction in response to dichotomous environments (e.g., sex, disease-affection status, or presence/absence of an exposure
Externí odkaz:
https://doaj.org/article/bc1a46a318494974a3fa1217972a98ac
Autor:
Miriam Aceves, Jose Granados, Ana C. Leandro, Juan Peralta, David C. Glahn, Sarah Williams-Blangero, Joanne E. Curran, John Blangero, Satish Kumar
Publikováno v:
Genes, Vol 15, Iss 5, p 569 (2024)
Currently, more than 55 million people around the world suffer from dementia, and Alzheimer’s Disease and Related Dementias (ADRD) accounts for nearly 60–70% of all those cases. The spread of Alzheimer’s Disease (AD) pathology and progressive n
Externí odkaz:
https://doaj.org/article/45407698c9874b26b4feaeb48ebc883f
Autor:
Satish Kumar, Jose Granados, Miriam Aceves, Juan Peralta, Ana C. Leandro, John Thomas, Sarah Williams-Blangero, Joanne E. Curran, John Blangero
Publikováno v:
Cells, Vol 13, Iss 5, p 369 (2024)
A large portion of the heterogeneity in coronavirus disease 2019 (COVID-19) susceptibility and severity of illness (SOI) remains poorly understood. Recent evidence suggests that SARS-CoV-2 infection-associated damage to alveolar epithelial type 2 cel
Externí odkaz:
https://doaj.org/article/9c3fd69acc1a41bc985f2a8ed9e0b651
Autor:
Vincent P. Diego, Eron G. Manusov, Xi Mao, Joanne E. Curran, Harald Göring, Marcio Almeida, Michael C. Mahaney, Juan M. Peralta, John Blangero, Sarah Williams-Blangero
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Socioeconomic status (SES) is a potent environmental determinant of health. To our knowledge, no assessment of genotype-environment interaction has been conducted to consider the joint effects of socioeconomic status and genetics on risk
Externí odkaz:
https://doaj.org/article/cb8641bc99dc4cb4bea6f454655a0072
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/5e820edf4a004a6bbd91bf6b3b4aad90
Autor:
Eron Grant Manusov, Vincent P. Diego, Khalid Sheikh, Sandra Laston, John Blangero, Sarah Williams-Blangero
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
This study examines the impact of G × E interaction effects on non-alcoholic fatty liver disease (NAFLD) among Mexican Americans in the Rio Grande Valley (RGV) of South Texas. We examined potential G × E interaction using variance components models
Externí odkaz:
https://doaj.org/article/10210474e0404354983f5fbeec198300
Autor:
Nicholas B. Blackburn, Laura F. Michael, Peter J. Meikle, Juan M. Peralta, Marian Mosior, Scott McAhren, Hai H. Bui, Melissa A. Bellinger, Corey Giles, Satish Kumar, Ana C. Leandro, Marcio Almeida, Jacquelyn M. Weir, Michael C. Mahaney, Thomas D. Dyer, Laura Almasy, John L. VandeBerg, Sarah Williams-Blangero, David C. Glahn, Ravindranath Duggirala, Mark Kowala, John Blangero, Joanne E. Curran
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1630-1639 (2019)
The de novo ceramide synthesis pathway is essential to human biology and health, but genetic influences remain unexplored. The core function of this pathway is the generation of biologically active ceramide from its precursor, dihydroceramide. Dihydr
Externí odkaz:
https://doaj.org/article/7f7fa522a72f41e89dbc1874ed90eccd
Autor:
Eron G. Manusov, Carolina Gomez De Ziegler, Vincent P. Diego, Gerardo Munoz-Monaco, Sarah Williams-Blangero
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Frailty is the age-related decline in well-being. The Frailty index (FI) measures the accumulation of health deficits and reflects biopsychosocial and cultural determinants of well-being. Frailty is measured as a static phenotype or as a Frailty Inde
Externí odkaz:
https://doaj.org/article/5793e2e6cad3490889b785589614b443