Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Sarah Watson"'
Autor:
Gabrielle Manteaux, Alix Amsel, Blanche Riquier-Morcant, Jaime Prieto Romero, Laurie Gayte, Benjamin Fourneaux, Marion Larroque, Nadège Gruel, Chloé Quignot, Gaelle Perot, Solenn Jacq, Madi Y. Cisse, Pascal Pomiès, Coralie Sengenes, Frédéric Chibon, Maud Heuillet, Floriant Bellvert, Sarah Watson, Sebastien Carrere, Nelly Firmin, Romain Riscal, Laetitia K. Linares
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Dedifferentiated and Well-differentiated liposarcoma are characterized by a systematic amplification of the Murine Double Minute 2 (MDM2) oncogene. We demonstrate that p53-independent metabolic functions of chromatin-bound MDM2 are exacerbat
Externí odkaz:
https://doaj.org/article/b0fec26a6a6443049f7aba6728e01c6f
Autor:
Nadège Gruel, Chloé Quignot, Laëtitia Lesage, Sophie El Zein, Sylvie Bonvalot, Dimitri Tzanis, Khadija Ait Rais, Fabien Quinquis, Bastien Manciot, Julien Vibert, Nadine El Tannir, Ahmed Dahmani, Héloïse Derrien, Didier Decaudin, Ivan Bièche, Laura Courtois, Odette Mariani, Laëtitia K. Linares, Laurie Gayte, Sylvain Baulande, Joshua J. Waterfall, Olivier Delattre, Gaëlle Pierron, Sarah Watson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Dedifferentiated liposarcoma (DDLPS) is the most frequent high-grade soft tissue sarcoma subtype. It is characterized by a component of undifferentiated tumor cells coexisting with a component of well-differentiated adipocytic tumor cells. B
Externí odkaz:
https://doaj.org/article/9071f50c747241d985e7d638e844b164
Autor:
Nicolas Jacquin, Ronan Flippot, Julien Masliah-Planchon, Guillaume Grisay, Riwan Brillet, Célia Dupain, Maud Kamal, Isabelle Guillou, Nadège Gruel, Nicolas Servant, Pierre Gestraud, Jennifer Wong, Vincent Cockenpot, Andreia Goncalves, Janick Selves, Hélène Blons, Etienne Rouleau, Olivier Delattre, Claire Gervais, Christophe Le Tourneau, Ivan Bièche, Yves Allory, Laurence Albigès, Sarah Watson
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-6 (2024)
Abstract Metastatic carcinoma of presumed renal origin (rCUP) has recently emerged as a new entity within the heterogeneous entity of Cancers of Unknown Primary (CUP) but their biological features and optimal therapeutic management remain unknown. We
Externí odkaz:
https://doaj.org/article/8884285fa1394307af735d86552e3c29
Autor:
Anne-Laure Genevois, Matthieu Carton, Myriam Jean-Denis, Joanna Cyrta, Nadège Corradini, Pablo Berlanga, Claire Chemin-Airiau, Charles Honore, Sophie El Zein, Anne-Sophie Defachelles, Emmanuelle Bompas, Philippe Anract, Justine Gantzer, Marie Karanian, Angélique Rome, Florence Duffaud, Christine Chevreau, Sarah Watson, Axel Le Cesne, Carmen Llacer, François Le Loarer, Gaëlle Pierron, François Gouin, Anne Gomez-Mascard, Sylvain Causeret, Françoise Ducimetière, Elsa Kalbacher, Maud Toulmonde, Jean-Yves Blay, Daniel Orbach
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100026- (2023)
Background: Leiomyosarcoma (LMS) and liposarcoma (LPS) are ultra-rare sarcomas in pediatric (0–18 years) and young adult (19−30) populations. We aimed to analyze their clinical characteristics at these young ages and to determine whether they sho
Externí odkaz:
https://doaj.org/article/ce7c19a233f041e78e3deea7fa01d9cf
Autor:
Mehdi Brahmi, Nathalie Gaspar, Justine Gantzer, Maud Toulmonde, Pascaline Boudou‐Rouquette, emmanuelle Bompas, Nelly Firmin, Thibaud Valentin, Mathilde Cancel, Florence Duffaud, Francois Bertucci, Christophe Perrin, Armelle Dufresne, Perrine Marec‐Bérard, Myriam Jean‐Denis, Isabelle Ray‐Coquard, Francois Le Loarer, Gaille Pierron, Franck Tirode, Jean‐Yves Blay, Sarah Watson
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 7801-7807 (2023)
Abstract Background CIC‐rearranged sarcomas (CIC‐RS) represent the most frequent subset of “Ewing‐like” undifferentiated small round cell sarcomas. These tumors tend to be more aggressive than Ewing sarcomas. Moreover, treatment strategy ca
Externí odkaz:
https://doaj.org/article/3384f7a641a44b0195ea12b9f77ba553
Autor:
Sarah Watson, Benjamin Verret, Stanislas Ropert, Julien Adam, Rastislav Bahleda, Sylvain Briand, Andrea Cavalcanti, Ali N. Chamseddine, Charles Court, Elie Fadel, Matthieu Faron, Leila Haddag‐Miliani, Clémence Henon, Cécile Le Pechoux, Antonin Levy, Olaf Mercier, Carine Ngo, Charles Honoré, Axel Le Cesne, Olivier Mir
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 3160-3166 (2023)
Abstract Gemcitabine has shown clinical activity against angiosarcoma in small series, alone, or combined with taxanes. We aimed to evaluate its activity as a single‐agent in a larger series of patients with advanced angiosarcoma. We retrospectivel
Externí odkaz:
https://doaj.org/article/778e03d4ac564846b7db152411c47d9f
Autor:
Yassine Bouchoucha, Arnault Tauziède‐Espariat, Arnaud Gauthier, Delphine Guillemot, Dorian Bochaton, Julien Vibert, Matthieu Carton, Sarah Watson, Sandrine Grossetête, Chloé Quignot, Daniel Orbach, Nadège Corradini, Gudrun Schleiermacher, Franck Bourdeaut, Marie Simbozel, Christelle Dufour, Véronique Minard‐Colin, Mehdi Brahmi, Franck Tirode, Daniel Pissaloux, Marie Karanian, Marie‐Christine Machet, Julien Masliah‐Planchon, Olivier Delattre, Liesbeth Cardoen, Gaëlle Pierron, François Doz
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 3, Pp 217-232 (2022)
Abstract BCOR‐ITD tumours form an emerging family of aggressive entities with an internal tandem duplication (ITD) in the last exon of the BCOR gene. The family includes cerebral tumours, termed central nervous system BCOR‐ITD (CNS BCOR‐ITD), a
Externí odkaz:
https://doaj.org/article/e02a318f290e402595038192d567159c
Autor:
Theodore Kareta, Cristina Thomas, Jian-Yang Li, Matthew M. Knight, Nicholas Moskovitz, Agata Rożek, Michele T. Bannister, Simone Ieva, Colin Snodgrass, Petr Pravec, Eileen V. Ryan, William H. Ryan, Eugene G. Fahnestock, Andrew S. Rivkin, Nancy Chabot, Alan Fitzsimmons, David Osip, Tim Lister, Gal Sarid, Masatoshi Hirabayashi, Tony Farnham, Gonzalo Tancredi, Patrick Michel, Richard Wainscoat, Rob Weryk, Bonnie Burrati, Jana Pittichová, Ryan Ridden-Harper, Nicole J. Tan, Paul Tristram, Tyler Brown, Mariangela Bonavita, Martin Burgdorf, Elahe Khalouei, Penelope Longa, Markus Rabus, Sedighe Sajadian, Uffe Graae Jorgensen, Martin Dominik, Jean-Baptiste Kikwaya, Elena Mazzotta Epifani, Elisabetta Dotto, Prasanna Deshapriya, Pedro Hasselmann, Massimo Dall’Ora, Lyu Abe, Tristan Guillot, Djamel Mékarnia, Abdelkrim Agabi, Philippe Bendjoya, Olga Suarez, Amaury Triaud, Thomas Gasparetto, Maximillian N. Günther, Michael Kueppers, Bruno Merin, Joseph Chatelain, Edward Gomez, Helen Usher, Cai Stoddard-Jones, Matthew Bartnik, Michael Bellaver, Brenna Chetan, Emma Dugan, Tori Fallon, Jeremy Fedewa, Caitlyn Gerhard, Seth A. Jacobson, Shane Painter, David-Michael Peterson, Joseph E. Rodriguez, Cody Smith, Kirill V. Sokolovsky, Hannah Sullivan, Kate Townley, Sarah Watson, Levi Webb, Josep M. Trigo-Rodríguez, Josep M. Llenas, Ignacio Pérez-García, A. J. Castro-Tirado, Jean-Baptiste Vincent, Alessandra Migliorini, Monica Lazzarin, Fiorangela La Forgia, Fabio Ferrari, Tom Polakis, Brian Skiff
Publikováno v:
The Astrophysical Journal Letters, Vol 959, Iss 1, p L12 (2023)
The impact of the Double Asteroid Redirection Test spacecraft into Dimorphos, moon of the asteroid Didymos, changed Dimorphos’s orbit substantially, largely from the ejection of material. We present results from 12 Earth-based facilities involved i
Externí odkaz:
https://doaj.org/article/019dcbfe191f434c91ccbfaea8970094
Autor:
Rajindra Napit, Prajwol Manandhar, Ajit Poudel, Pragun G. Rajbhandari, Sarah Watson, Sapana Shakya, Saman M. Pradhan, Ajay N. Sharma, Ashok Chaudhary, Christine K. Johnson, Jonna K. Mazet, Dibesh Karmacharya
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Campylobacter spp. is often underreported and underrated bacteria that present real health risks to both humans and animals, including non-human primates. It is a commensal microorganism of gastrointestinal tract known to cause gastroenteritis in hum
Externí odkaz:
https://doaj.org/article/4ea1d31fc334417c873846a5089d0a0a
Autor:
Sarah Watson, Collette A. LaVigne, Lin Xu, Didier Surdez, Joanna Cyrta, Delia Calderon, Matthew V. Cannon, Matthew R. Kent, Katherine M. Silvius, Jack P. Kucinski, Emma N. Harrison, Whitney Murchison, Dinesh Rakheja, Franck Tirode, Olivier Delattre, James F. Amatruda, Genevieve C. Kendall
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112013- (2023)
Summary: Clinical sequencing efforts are rapidly identifying sarcoma gene fusions that lack functional validation. An example is the fusion of transcriptional coactivators, VGLL2-NCOA2, found in infantile rhabdomyosarcoma. To delineate VGLL2-NCOA2 tu
Externí odkaz:
https://doaj.org/article/fdc0828e193b44cf881e6eb5e4a6a484