Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sarah Warsi"'
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Autor:
Fatemeh Safi, Parashar Dhapola, Sarah Warsi, Mikael Sommarin, Eva Erlandsson, Jonas Ungerbäck, Rebecca Warfvinge, Ewa Sitnicka, David Bryder, Charlotta Böiers, Ram Krishna Thakur, Göran Karlsson
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113357- (2023)
Externí odkaz:
https://doaj.org/article/afa99b9a000946b79b1053681bd6ceed
Autor:
Sarah Warsi, Maria Dahl, Emma M. K. Smith, Anna Rydstrom, Els Mansell, Valgardur Sigurdsson, Julia Sjoberg, Shamit Soneji, Emma Rorby, Kavitha Siva, Tan H. M. Grahn, Yang Liu, Ulrika Blank, Goran Karlsson, Stefan Karlsson
Publikováno v:
Haematologica, Vol 107, Iss 12 (2022)
Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incomp
Externí odkaz:
https://doaj.org/article/89aef74030df4d8c80376944eafe6730
Autor:
Maria Dahl, Emma M.K. Smith, Sarah Warsi, Michael Rothe, Maria J. Ferraz, Johannes M.F.G. Aerts, Azadeh Golipour, Claudia Harper, Richard Pfeifer, Daniella Pizzurro, Axel Schambach, Chris Mason, Stefan Karlsson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 312-323 (2021)
Gaucher disease type 1 (GD1) is an inherited lysosomal disorder with multisystemic effects in patients. Hallmark symptoms include hepatosplenomegaly, cytopenias, and bone disease with varying degrees of severity. Mutations in a single gene, glucosida
Externí odkaz:
https://doaj.org/article/07372d5f46f04d9c947be435687180aa
Autor:
Yang Liu, Maria Dahl, Shubhranshu Debnath, Michael Rothe, Emma M. Smith, Tan Hooi Min Grahn, Sarah Warsi, Jun Chen, Johan Flygare, Axel Schambach, Stefan Karlsson
Publikováno v:
Haematologica, Vol 107, Iss 2 (2021)
Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure disorder in which pure red blood cell aplasia is associated with physical malformations and a predisposition to cancer. Twentyfive percent of patients with DBA have mutations in a gene
Externí odkaz:
https://doaj.org/article/87a6fd29702a4a00ac393a879706be89
Autor:
Sarah Warsi, Ulrika Blank, Maria Dahl, Tan Hooi Min Grahn, Ludwig Schmiderer, Silja Andradottir, Stefan Karlsson
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
Life-long production of blood from hematopoietic stem cells (HSCs) is a process of strict modulation. Intrinsic and extrinsic signals govern fate options like self-renewal - a cardinal feature of HSCs. Bone morphogenetic proteins (BMP) have an establ
Externí odkaz:
https://doaj.org/article/37bbd038d752424c8e2625681ba76262
Autor:
Mathias, Hochgerner, Thomas, Bauer, Victoria, Zyulina, Elisabeth, Glitzner, Sarah, Warsi, Joanne E, Konkel, Carmen, Tam-Amersdorfer, Wanjun, Chen, Stefan, Karlsson, Maria, Sibilia, Herbert, Strobl
Publikováno v:
The Journal of investigative dermatology. 142(9)
The cytokine TGFβ1 induces epidermal Langerhans cell (LC) differentiation from human precursors, an effect mediated through BMPR1a/ALK3 signaling, as revealed from ectopic expression and receptor inhibition studies. Whether TGFβ1‒BMPR1a signaling
Autor:
Sarah, Warsi, Maria, Dahl, Emma M K, Smith, Anna, Rydstrom, Els, Mansell, Valgardur, Sigurdsson, Julia, Sjoberg, Shamit, Soneji, Emma, Rorby, Kavitha, Siva, Tan H M, Grahn, Yang, Liu, Ulrika, Blank, Goran, Karlsson, Stefan, Karlsson
Publikováno v:
Haematologica. 107(12)
Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incomp
Autor:
Mathias Hochgerner, Thomas Bauer, Victoria Zyulina, Elisabeth Glitzner, Sarah Warsi, Joanne E. Konkel, Carmen Tam-Amersdorfer, Wanjun Chen, Stefan Karlsson, Maria Sibilia, Herbert Strobl
Publikováno v:
Journal of Investigative Dermatology. 142:2446-2454.e3
Autor:
Dominik Turkiewicz, Per Engström, Sarah Warsi, Stig Lenhoff, Stina Wichert, Jacob Engellau, Sven Bäck, André Haraldsson, Silke Engelholm
Publikováno v:
European journal of haematologyREFERENCES. 107(4)
Objectives: Total body irradiation (TBI) is commonly used prior to hematopoietic stem cell transplantation (HSCT) in myeloablative conditioning regimens. However, TBI may be replaced by total marrow irradiation (TMI) at centres with access to Helical
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Autor:
Fatemeh, Safi, Parashar, Dhapola, Sarah, Warsi, Mikael, Sommarin, Eva, Erlandsson, Jonas, Ungerbäck, Rebecca, Warfvinge, Ewa, Sitnicka, David, Bryder, Charlotta, Böiers, Ram Krishna, Thakur, Göran, Karlsson
Publikováno v:
Cell Reports. 39:110798
The emerging notion of hematopoietic stem and progenitor cells (HSPCs) as a low-primed cloud without sharply demarcated gene expression programs raises the question on how cellular-fate options emerge and at which stem-like stage lineage priming is i