Výsledky vyhledávání - "Sarah Waldie"

SARS-CoV-2 spike protein removes lipids from model membranes and interferes with the capacity of high density lipoprotein to exchange lipids

Autor: Yubexi Correa, V. Trevor Forsyth, Harald Pichler, Michael Haertlein, Franck Fieschi, Sarah Waldie, Marité Cárdenas, Michel Thépaut, Martine Moulin, Samantha Micciulla

Publikováno v: Journal of Colloid and Interface Science
Journal of Colloid and Interface Science, 2021, 602, pp.732-739. ⟨10.1016/j.jcis.2021.06.056⟩
'Journal of Colloid and Interface Science ', vol: 602, pages: 732-739 (2021)
Journal of Colloid and Interface Science, Elsevier, 2021, 602, pp.732-739. ⟨10.1016/j.jcis.2021.06.056⟩

Graphical abstract
Cholesterol has been shown to affect the extent of coronavirus binding and fusion to cellular membranes. The severity of Covid-19 infection is also known to be correlated with lipid disorders. Furthermore, the levels of both s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c862f66a4ce991b126eaaa86b26a55c
https://doi.org/10.1016/j.jcis.2021.06.056

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Structural Characterisation of Nanoparticle-Supported Lipid Bilayers by Grazing Incidence X-ray and Neutron Scattering

Autor: Nicolò Paracini, Philipp Gutfreund, Rebecca Welbourn, Juan Francisco Gonzalez, Kexin Zhu, Yansong Miao, Nageshwar Yepuri, Tamim A Darwish, Christopher Garvey, Sarah Waldie, Johan Larsson, Max Wolff, Marité Cárdenas

The structure of supported lipid bilayers formed on a monolayer of nanoparticles was determined using a combination of grazing incidence X-ray and neutron scattering techniques. Ordered nanoparticle arrays assembled on a silicon crystal using a Langm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73283c349989a52c81cd3f25216d261e
https://doi.org/10.1101/2022.07.07.499146

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Structure of Lipoproteins and Their Capacity for Lipid Exchange : Relevance for Development of Atherosclerosis and its Treatment by HDL Therapy

Autor: Sarah Waldie, Rita Del Giudice, Marité Cárdenas

Atherosclerosis, the largest killer in the western world, arises from build-up of plaques at the artery walls and can result in cardiovascular disease. Low- and high-density lipoproteins are involved in the disease development by depositing and remov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c184ba742f2ee5ed697a0f2d774647b
http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-49145

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Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles

Autor: Venkata R. Krishnamurthy, Marianna Yanez Arteta, Michael Lerche, Martine Moulin, Michael Haertlein, Christian Lang, Lennart Lindfors, V. Trevor Forsyth, Harald Pichler, Tamim A. Darwish, Robert A. Russell, Federica Sebastiani, Ryan A. Bragg, Lionel Porcar, Marité Cárdenas, Charles S. Elmore, Sarah Waldie

Publikováno v: ACS nano 15(4), 6709-6722 (2021). doi:10.1021/acsnano.0c10064
'ACS Nano ', vol: 15, pages: 6709-6722 (2021)
ACS Nano

Emerging therapeutic treatments based on the production of proteins by delivering mRNA have become increasingly important in recent times. While lipid nanoparticles (LNPs) are approved vehicles for small interfering RNA delivery, there are still chal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4e4b06ff3ca666c2ae9c5815ba89b6
https://hdl.handle.net/2128/27729

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Model Membranes and Their Interactions with Native and Artificial Lipoproteins

Autor: Sarah Waldie

Atherosclerosis arises from build-up of plaque in the blood, can result in cardiovascular disease and is the largest killer in the west. Low- and high-density lipoproteins are involved in the disease development by depositing and removing lipids to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375d3b575f0f4f5c804d6f29dfc406e0
https://doi.org/10.24834/isbn.9789178771325

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Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol

Autor: Tamim A. Darwish, Gernot Strohmeier, Tania Kjellerup Lind, Martin Malmsten, V. Trevor Forsyth, Harald Pichler, Marité Cárdenas, Kathryn L. Browning, Sarah Waldie, Michael Haertlein, Martine Moulin, Armando Maestro, Federica Sebastiani, Maximilian W. A. Skoda, Selma Maric, Nageshwar R. Yepuri, Eva Bengtsson

Publikováno v: 'Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids ', vol: 1865, pages: 158769-1-158769-8 (2020)
Waldie, S, Sebastiani, F, Browning, K, Maric, S, Lind, T K, Yepuri, N, Darwish, T A, Moulin, M, Strohmeier, G, Pichler, H, Skoda, M W A, Maestro, A, Haertlein, M, Forsyth, V T, Bengtsson, E, Malmsten, M & Cardenas, M 2020, ' Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol ', B B A-Molecular and Cell Biology of Lipids, vol. 1865, no. 10, 158769 . https://doi.org/10.1016/j.bbalip.2020.158769

Lipoproteins play a central role in the development of atherosclerosis. High and low-density lipoproteins (HDL and LDL), known as ‘good’ and ‘bad’ cholesterol, respectively, remove and/or deposit lipids into the artery wall. Hence, insight in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819dbfc207b7d328875256c4f1080d84
https://doi.org/10.1016/j.bbalip.2020.158769

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