Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sarah Wachtel"'
Autor:
Matthew Wickersham, Sarah Wachtel, Tania Wong Fok Lung, Grace Soong, Rudy Jacquet, Anthony Richardson, Dane Parker, Alice Prince
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2742-2751 (2017)
Human skin is commonly colonized and infected by Staphylococcus aureus. Exactly how these organisms are sensed by keratinocytes has not been clearly delineated. Using a combination of metabolic and transcriptomic methodologies, we found that S. aureu
Externí odkaz:
https://doaj.org/article/7742d5d0bcdc4bff8b4c93324a2a4974
Autor:
Kipyegon Kitur, Sarah Wachtel, Armand Brown, Matthew Wickersham, Franklin Paulino, Hernán F. Peñaloza, Grace Soong, Susan Bueno, Dane Parker, Alice Prince
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2219-2230 (2016)
Staphylococcus aureus triggers inflammation through inflammasome activation and recruitment of neutrophils, responses that are critical for pathogen clearance but are associated with substantial tissue damage. We postulated that necroptosis, cell dea
Externí odkaz:
https://doaj.org/article/6826f89d91474684a9cc047c09ba3385
Autor:
Jérôme Tourret, Benjamin P Willing, Matthew A Croxen, Nicolas Dufour, Sara Dion, Sarah Wachtel, Erick Denamur, B Brett Finlay
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153034 (2016)
Uropathogenic Escherichia coli (UPEC) strains live as commensals in the digestive tract of the host, but they can also initiate urinary tract infections. The aim of this work was to determine how a host detects the presence of a new UPEC strain in th
Externí odkaz:
https://doaj.org/article/dbb0ff792dd94c9a9395f462f78a7034
Autor:
Grace Soong, Franklin Paulino, Sarah Wachtel, Dane Parker, Matthew Wickersham, Dongni Zhang, Armand Brown, Christine Lauren, Margaret Dowd, Emily West, Basil Horst, Paul Planet, Alice Prince
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT Skin is the most common site of Staphylococcus aureus infection. While most of these infections are self-limited, recurrent infections are common. Keratinocytes and recruited immune cells participate in skin defense against infection. We pos
Externí odkaz:
https://doaj.org/article/a4d1954899034b38937686727a8fa46e
Autor:
Kipyegon Kitur, Dane Parker, Pamela Nieto, Danielle S Ahn, Taylor S Cohen, Samuel Chung, Sarah Wachtel, Susan Bueno, Alice Prince
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004820 (2015)
Staphylococcus aureus USA300 strains cause a highly inflammatory necrotizing pneumonia. The virulence of this strain has been attributed to its expression of multiple toxins that have diverse targets including ADAM10, NLRP3 and CD11b. We demonstrate
Externí odkaz:
https://doaj.org/article/20f9939c2b014b2fb3457996ec952c9d
Publikováno v:
Journal of hospital medicineREFERENCES. 17(2)
Autor:
Kay-Marie Lamar, Rui Yang, Ann Harris, Andrew D. Hoffmann, Sujana Ghosh, Shih Hsing Leir, Sara L. Fossum, Matthew Xu, Jenny L. Kerschner, Sarah Wachtel, Lindsay R. Stolzenburg
Publikováno v:
Nucleic Acids Research
Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cystic fibrosis (CF), but are not good predictors of lung phenotype. Genome-wide association studies (GWAS) previously identified additional genomic sites associat
Autor:
Anthony R. Richardson, Alice Prince, Dane Parker, Sarah Wachtel, Tania Wong Fok Lung, Matthew Wickersham, Grace Soong, Rudy Jacquet
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2742-2751 (2017)
Human skin is commonly colonized and infected by Staphylococcus aureus. Exactly how these organisms are sensed by keratinocytes has not been clearly delineated. Using a combination of metabolic and transcriptomic methodologies, we found that S. aureu
Autor:
Hernán F. Peñaloza, Kipyegon Kitur, Franklin Paulino, Sarah Wachtel, Armand O. Brown, Grace Soong, Matthew Wickersham, Susan M. Bueno, Alice Prince, Dane Parker
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2219-2230 (2016)
SummaryStaphylococcus aureus triggers inflammation through inflammasome activation and recruitment of neutrophils, responses that are critical for pathogen clearance but are associated with substantial tissue damage. We postulated that necroptosis, c
Autor:
Sarah Wachtel, Marc-Andreas Edel, Thomas Forkmann, Tobias Teismann, Peter Nyhuis, Heide Glaesmer
Publikováno v:
Psychiatry Research. 226:264-272
The interpersonal theory of suicide (Joiner, T.E., 2005. Why People Die By Suicide. Harvard University Press, Cambridge) postulates that, for a serious or lethal suicide attempt one has to possess a desire to die and the capability to commit suicide.