The Yorkshire Kidney Screening Trial (YKST): protocol for a feasibility study of adding non-contrast abdominal CT scanning to screen for kidney cancer and other abdominal pathology within a trial of community-based CT screening for lung cancer

Autor: Richard D Neal, David Hammond, Matthew E J Callister, Stephen J Sharp, Andrew Smith, Matthew Ward, Juliet A Usher-Smith, Sabrina H Rossi, Neil Hancock, Grant D Stewart, Jon Cartledge, Michael Kimuli, Philip A J Crosbie, Evis Sala, Suzanne Rogerson, Sarah W Burge, Tom Wallace, Irene Simmonds, Fiona Farquhar, Angela Godoy, Simon Burbidge, Claire Eckert, Gareth R Iball, Golnessa Masson

Publikováno v: BMJ Open, Vol 12, Iss 9 (2022)

Introduction Kidney cancer (renal cell cancer (RCC)) is the seventh most common cancer in the UK. As RCC is largely curable if detected at an early stage and most patients have no symptoms, there is international interest in evaluating a screening pr

Externí odkaz: https://doaj.org/article/c99c7dc2fd4543c7b45ec578854bdb64

The Yorkshire Kidney Screening Trial (YKST):protocol for a feasibility study of adding non-contrast abdominal CT scanning to screen for kidney cancer and other abdominal pathology within a trial of community-based CT screening for lung cancer

Autor: Juliet A Usher-Smith, Angela Godoy, Sarah W Burge, Simon Burbidge, Jon Cartledge, Philip A J Crosbie, Claire Eckert, Fiona Farquhar, David Hammond, Neil Hancock, Gareth R Iball, Michael Kimuli, Golnessa Masson, Richard D Neal, Suzanne Rogerson, Sabrina H Rossi, Evis Sala, Andrew Smith, Stephen J Sharp, Irene Simmonds, Tom Wallace, Matthew Ward, Matthew E J Callister, Grant D Stewart

Publikováno v: Usher-Smith, J A, Godoy, A, Burge, S W, Burbidge, S, Cartledge, J, Crosbie, P A J, Eckert, C, Farquhar, F, Hammond, D, Hancock, N, Iball, G R, Kimuli, M, Masson, G, Neal, R D, Rogerson, S, Rossi, S H, Sala, E, Smith, A, Sharp, S J, Simmonds, I, Wallace, T, Ward, M, Callister, M E J & Stewart, G D 2022, ' The Yorkshire Kidney Screening Trial (YKST) : protocol for a feasibility study of adding non-contrast abdominal CT scanning to screen for kidney cancer and other abdominal pathology within a trial of community-based CT screening for lung cancer ', BMJ Open, vol. 12, no. 9, e063018 . https://doi.org/10.1136/bmjopen-2022-063018

Peer reviewed: True
Acknowledgements: The authors thank the patient and public representations who have contributed to this study, Phil Alsop and Philip Dondi. They also thank the YLST study team and members of the YKST IDMC (Paul Nathan (Chair)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3200d75677a712027c51b8734e09cdf
https://research.manchester.ac.uk/en/publications/a2ae91ab-f98c-4537-aeb4-62de584e61b3

Conservation and losses of non-coding RNAs in avian genomes.

Autor: Paul P Gardner, Mario Fasold, Sarah W Burge, Maria Ninova, Jana Hertel, Stephanie Kehr, Tammy E Steeves, Sam Griffiths-Jones, Peter F Stadler

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0121797 (2015)

Here we present the results of a large-scale bioinformatics annotation of non-coding RNA loci in 48 avian genomes. Our approach uses probabilistic models of hand-curated families from the Rfam database to infer conserved RNA families within each avia

Externí odkaz: https://doaj.org/article/408ad17cc92d45ac9267402cd81489ed

A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells

Autor: Laura Woods, Claire E. Senner, Hanneke Okkenhaug, Vicente Perez-Garcia, Stephanie Chrysanthou, Myriam Hemberger, Sarah W. Burge, Elena Fineberg

Publikováno v: Stem Cell Reports
Stem Cell Reports, Vol 10, Iss 4, Pp 1355-1368 (2018)

Summary The ten-eleven translocation (TET) proteins are well known for their role in maintaining naive pluripotency of embryonic stem cells. Here, we demonstrate that, jointly, TET1 and TET2 also safeguard the self-renewal potential of trophoblast st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8362dac6e1ca6da1870b278f810c7a34
http://europepmc.org/articles/PMC5998911

RNAcentral: an international database of ncRNA sequences

Autor: Robert D. Finn, Nam-Hai Chua, Paul J. Kersey, Runsheng Chen, Mathew W. Wright, Weimin Zhu, Geir Skogerbø, Kim D. Pruitt, Robin R. Gutell, Benli Chai, Simon Kay, Alex Bateman, J. Michael Cherry, His Yuan Huang, Artemis G. Hatzigeorgiou, Patricia P. Chan, Eugene Kulesha, Kelly P. Williams, Elspeth A. Bruford, Anton I. Petrov, Sam Griffiths-Jones, Jacek Wower, Michael B. Clark, Janusz M. Bujnicki, Xiu Cheng Quek, Yi Zhao, Hsien Da Huang, Christian W Zwieb, Marcel E. Dinger, Sarah W. Burge, Huan Wang, Richard Gibson, Todd M. Lowe, Guy Cochrane, Jun Liu, James R. Cole, Dan Staines, Corey M. Hudson, Jennifer Harrow

Publikováno v: Nucleic Acids Research
Griffiths-Jones, S 2014, ' RNAcentral: an international database of ncRNA sequences. ', Nucleic acids research . https://doi.org/10.1093/nar/gku991

The field of non-coding RNA biology has been hampered by the lack of availability of a comprehensive, up-to-date collection of accessioned RNA sequences. Here we present the first release of RNAcentral, a database that collates and integrates informa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a383da0f6af748e5f3b3b0845212eec
https://doi.org/10.1093/nar/gku991