Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sarah Volpert"'
Autor:
Steffen Koschmieder, Carsten Müller-Tidow, Wolfgang E. Berdel, A Berkemeier, M Stelljes, P Wieacker, Thomas Burmeister, Gerda Silling, Sarah Volpert, N. Gökbuget, Monika Brüggemann
Publikováno v:
Leukemia. 28:419-422
Molecular monitoring in NUP214-ABL -positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy
Autor:
Hans-Heinrich Wolf, Achim Heinecke, Nicola Lang, Martin Kropff, Joachim Kienast, Wolfgang E. Berdel, Monika Engelhardt, Hermann Einsele, Peter Liebisch, M. Hentrich, Hans Salwender, Tobias Dechow, Bernd Metzner, Guido Bisping, Orhan Sezer, Elke Schuck, Sarah Volpert, Nicolaus Kröger
Publikováno v:
British Journal of Haematology. 138:330-337
A phase 2 trial was performed to study the combination of bortezomib (VELCADE) with intermediate-dose dexamethasone (DEX), and continuous low-dose oral cyclophosphamide (CY) in patients with relapsed multiple myeloma (MM). Fifty-four patients with ad
Publikováno v:
Cancer Genetics and Cytogenetics. 165:180-184
Reciprocal translocations involving the MYC locus and immunoglobulin heavy chain (IGH) and light chain (IgK and IgL) loci are characteristic for non-Hodgkin lymphomas, especially Burkitt lymphoma, and have been described in B-cell acute lymphoblastic
Autor:
Joelle Tchinda, Jürgen Horst, Wolfgang E. Berdel, Sarah Volpert, Thomas Büchner, Thomas Neumann
Publikováno v:
Diagnostic Molecular Pathology. 13:190-195
Sincechromosomalchangesareusedbothasindependentprognostic factors and for therapy design in hematological disorders,itisnecessarytoelucidatechromosomalchangesasaccuratelyaspos-sible. We used spectral karyotyping (SKY) and fluorescence in situhybridiz
Autor:
Thomas Neumann, Ruediger Liersch, Wolfgang E. Berdel, Ingo Kennerknecht, Michael Zühlsdorf, Joelle Tchinda, Th. Büchner, Jürgen Horst, Sarah Volpert, Hubert Serve
Publikováno v:
Leukemia. 18:183-186
A cryptic insertion (17;15) on both chromosomes 17 with lack of PML–RARA expression in a case of atypical acute promyelocytic leukemia
Autor:
Jörg Ritter, Jürgen Horst, Thomas Neumann, Joelle Tchinda, Sarah Volpert, Ingo Kennerknecht, Wolfgang E. Berdel, T. Büchner
Publikováno v:
Cancer Genetics and Cytogenetics. 133:61-65
Cytogenetic studies can be useful in the clinical management of patients with leukemia. They may also give a clue to leukemogenesis and/or pathogenesis. Numerous disease-specific chromosomal aberrations have been and continue to be identified. Transl
Autor:
Matthias Stelljes, Sarah Volpert, Martin Kropff, Joachim Kienast, Carsten Müller-Tidow, Guido Bisping, Frank Hilberg, Doris Wenning, Gerald Juergen Roth, Rolf M. Mesters, Martin Stefanic, Dirk Gustavus, Gerd Munzert, Wolfgang E. Berdel
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 15(2)
Purpose: Novel drugs including targeted approaches have changed treatment paradigms for multiple myeloma (MM) and may also have therapeutic potential in the poor-prognosis t(4;14) subset; t(4;14) results in overexpressed and activated fibroblast grow
Autor:
Joëlle Tchinda, Sarah Volpert, Martin Kropff, Wolfgang E. Berdel, Joachim Kienast, Friedhelm Meinhardt, Jürgen Horst
Publikováno v:
American journal of clinical pathology. 122(6)
A number of genetic abnormalities have been detected in multiple myeloma (MM) using cytogenetic techniques. The prominent abnormalities are deletions of 13q and translocations affecting the IgH locus on 14q32. The recurrence of chromosomal abnormalit
Autor:
Wolfgang E. Berdel, Doris Wenning, Joelle Tchinda, Guido Bisping, Martin Kropff, Joachim Kienast, Sarah Volpert
Publikováno v:
Leukemia research. 29(5)
Fifteen patients with advanced multiple myeloma were scheduled to receive bortezomib 1.3 mg/m2 IV days 1, 4, 8, and 11 every 3 weeks for eight cycles in combination with dexamethasone. One patient (7%) achieved a complete response, 10 (67%) a partial
Autor:
Sarah Volpert, Thomas Büchner, Joelle Tchinda, Nicole McNeil, Eva Hilgenfeld, Thomas Ried, Wolfgang E. Berdel, Hubert Serve, Thomas Neumann, Ingo Kennerknecht, Jürgen Horst
Publikováno v:
Leukemialymphoma. 44(11)
Cytogenetic data have significantly contributed to our understanding of the heterogeneity of acute myeloid leukemia (AML). In AML, numerous recurrent chromosomal aberrations have been identified, and several of them, e.g. t(8;21)(q22;q22), t(15;17)(q