Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sarah Vollett"'
Autor:
Courteney K Lai, Yeonsook Moon, Florian Kuchenbauer, Daniel T Starzcynowski, Bob Argiropoulos, Eric Yung, Philip Beer, Adrian Schwarzer, Amit Sharma, Gyeongsin Park, Malina Leung, Grace Lin, Sarah Vollett, Stephen Fung, Connie J Eaves, Aly Karsan, Andrew P Weng, R Keith Humphries, Michael Heuser
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112671 (2014)
Extensive molecular profiling of leukemias and preleukemic diseases has revealed that distinct clinical entities, like acute myeloid (AML) and T-lymphoblastic leukemia (T-ALL), share similar pathogenetic mutations. It is not well understood how the c
Externí odkaz:
https://doaj.org/article/ef4a04d6af37476aa1377dc32893568c
Autor:
Karen K Y Lam, Xingji Zheng, Roberto Forestieri, Aruna D Balgi, Matt Nodwell, Sarah Vollett, Hilary J Anderson, Raymond J Andersen, Yossef Av-Gay, Michel Roberge
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002691 (2012)
Tuberculosis, caused by Mycobacterium tuberculosis infection, is a major cause of morbidity and mortality in the world today. M. tuberculosis hijacks the phagosome-lysosome trafficking pathway to escape clearance from infected macrophages. There is i
Externí odkaz:
https://doaj.org/article/b5b29aa927074b68b0fa10d67f939761
Autor:
Gregg B. Morin, Sarah Vollett, Vicky C.-D. Chang, Marco A. Marra, S.-W. Grace Cheng, Annie Moradian, Malachi Griffith, Michael A. Kuzyk, Taka-Aki Ichu, Jerry F. Tien
Publikováno v:
Molecular and Cellular Biology. 32:4691-4704
CrkRS (Cdc2-related kinase, Arg/Ser), or cyclin-dependent kinase 12 (CKD12), is a serine/threonine kinase believed to coordinate transcription and RNA splicing. While CDK12/CrkRS complexes were known to phosphorylate the C-terminal domain (CTD) of RN
Autor:
Sandy Wong, Courteney Lai, Sarah Vollett, Adrian Wan, R. Keith Humphries, Bob Argiropoulos, Malina Leung, Eric Yung, Vicky C.-D. Chang, Sanja Sekulovic, Tobias Berg
Publikováno v:
Leukemia Research. 35:545-550
To determine the contribution of the common N-terminal truncation of NUP98 in NUP98-translocations resulting in acute myeloid leukemia, we have conducted a structure-function analysis of NUP98 in the context of NUP98-HOXA10HD, a novel, canonical NUP9
Autor:
Adrian Schwarzer, Florian Kuchenbauer, Sarah Vollett, Gyeongsin Park, Bob Argiropoulos, Michael Heuser, Eric Yung, Stephen Fung, Courteney Lai, Aly Karsan, Daniel T. Starzcynowski, Malina Leung, Philip A. Beer, R. Keith Humphries, Amit Sharma, Connie J. Eaves, Yeonsook Moon, Grace Lin, Andrew P. Weng
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e112671 (2014)
PLoS ONE, Vol 9, Iss 11, p e112671 (2014)
Extensive molecular profiling of leukemias and preleukemic diseases has revealed that distinct clinical entities, like acute myeloid (AML) and T-lymphoblastic leukemia (T-ALL), share similar pathogenetic mutations. It is not well understood how the c
Autor:
Florian Kuchenbauer, Sarah Vollett, Michael Heuser, Yeonsook Moon, Tobias Berg, Gyeongsin Park, R. Keith Humphries, Courteney Lai, Ping Xiang
Publikováno v:
Experimental hematology. 38(3)
Objective Transcriptional control of hematopoietic lineage fate relies on the integration of many intra- and extracellular signals. To test whether the microenvironment impacts on leukemic phenotype, we exploited the MN1 model of acute myeloid leukem
Autor:
Sarah Vollett, Raymond J. Andersen, Karen K. Y. Lam, Hilary J. Anderson, Aruna D. Balgi, Yossef Av-Gay, Matt Nodwell, Roberto Forestieri, Michel Roberge, Xingji Zheng
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002691 (2012)
PLoS Pathogens
PLoS Pathogens
Tuberculosis, caused by Mycobacterium tuberculosis infection, is a major cause of morbidity and mortality in the world today. M. tuberculosis hijacks the phagosome-lysosome trafficking pathway to escape clearance from infected macrophages. There is i
Autor:
Sarah Vollett, Eric Yung, Bob Argiropoulos, Grace Lin, Michael Heuser, Gyeongsin Park, Malina Leung, Arnold Ganser, Florian Kuchenbauer, Courteney Lai, Piper Jessica, R. Keith Humphries
Publikováno v:
Blood. 116:229-229
Abstract 229 Overexpression of MN1 (meningioma 1) is a negative prognostic factor in acute myeloid leukemia (AML) patients with normal cytogenetics, and induces a rapidly lethal AML in mice. We have shown previously that MN1, a transcription cofactor
Autor:
Courteney Lai, Sarah Vollett, R. Keith Humphries, Ping Xiang, Michael Heuser, Malina Leung, Geyongsin Park, Grace Lin
Publikováno v:
Blood. 112:2420-2420
Transcriptional control of hematopoietic lineage fate relies on the integration of a multitude of intra- and extracellular signals. Interestingly, the leukemic phenotype of MLL-rearranged leukemias has recently been shown also to depend on signals fr