Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sarah Vierkotten"'
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 8, Pp 877-890 (2015)
The alveolar epithelium represents a major site of tissue destruction during lung injury. It consists of alveolar epithelial type I (ATI) and type II (ATII) cells. ATII cells are capable of self-renewal and exert progenitor function for ATI cells upo
Externí odkaz:
https://doaj.org/article/3b61ca0e185b40cbb3bf83954da29072
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22959 (2011)
Variants in the chromosomal region 10q26 are strongly associated with an increased risk for age-related macular degeneration (AMD). Two potential AMD genes are located in this region: ARMS2 and HTRA1 (high-temperature requirement A1). Previous studie
Externí odkaz:
https://doaj.org/article/237e5410cb8e41eebd622d5a4ff945aa
Autor:
Ursula Storch, Sarah Vierkotten, Susanne Fiedler, Jonas Weber, Ali Önder Yildirim, Stephan Klee, Wolfgang Zwickenpflug, Katharina Hofmann, Thomas Gudermann, Veit Flockerzi, Jie Jia, Melanie Königshoff, Alexander Dietrich
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:560-568
Pulmonary fibrosis (PF) is a chronic progressive lung disease without effective medical treatment options leading to respiratory failure and death within 3-5years of diagnosis. The pathological process of PF is driven by aberrant wound-healing involv
Autor:
Gerhard Preissler, Oliver Eickelberg, Arunima Sengupta, Gerald Burgstaller, Michael Lindner, Melanie Königshoff, Jürgen Behr, Sarah Vierkotten
Publikováno v:
Am. J. Physiol. Lung Cell Mol. Physiol. 314, L708-L723 (2018)
Cues from the extracellular matrix (ECM) and their functional interplay with cells play pivotal roles for development, tissue repair, and disease. However, the precise nature of this interplay remains elusive. We used an innovative 3D cell culture EC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de7e98e160b525c0d4f86d36dde2bc0
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=52749
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=52749
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 8, Pp 877-890 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms
The alveolar epithelium represents a major site of tissue destruction during lung injury. It consists of alveolar epithelial type I (ATI) and type II (ATII) cells. ATII cells are capable of self-renewal and exert progenitor function for ATI cells upo
Autor:
Silke Meiners, Gerald Burgstaller, Oliver Eickelberg, Rita Costa, Melanie Königshoff, Michael Lindner, Darcy E. Wagner, Franziska E. Uhl, Sarah Vierkotten, Ina Koch
Publikováno v:
Eur. Respir. J. 46, 1150-1166 (2015)
Chronic obstructive pulmonary disease (COPD) is characterised by a progressive loss of lung tissue. Inducing repair processes within the adult diseased lung is of major interest and Wnt/β-catenin signalling represents a promising target for lung rep
Autor:
Bernd Kirchhof, Philipp S. Muether, Manuel M. Hermann, Sarah Vierkotten, Robert Hoerster, Sascha Fauser
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 252:11-16
Proliferative vitreoretinopathy (PVR) is characterized by epithelial to mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cells and consecutive formation of fibrous membranes, leading to retinal redetachment. Transforming growth factor
Autor:
Michaela Aichler, Marion Frankenberger, Axel Walch, Melanie Königshoff, Sarah Vierkotten, Aina Martin, Jürgen Behr, Thomas Höfer
Publikováno v:
ERS Lung Science Conference 2016.
Objective: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology characterized by epithelial injury, myofibroblast activation, and extracellular matrix deposition. Reactivation of WNT/β-catenin pathway has been linked to t
Autor:
Stephanie Carnesecchi, Rachel C. Chambers, Constance Barazzone-Argiroffo, Cecilia M. Prêle, Irmgard Irminger-Finger, Bruno Crestani, Geoffrey J. Laurent, Jean-Claude Pache, Sarah Vierkotten, Melanie Königshoff, Yves Donati, Pierre-Alain André
Publikováno v:
Respir. Res. 16:118 (2015)
Respiratory Research, Vol. 16 (2015) P. 118
Respiratory Research
Respiratory Research, Vol. 16 (2015) P. 118
Respiratory Research
Background Idiopathic pulmonary fibrosis (IPF) is a rapid progressive fibro-proliferative disorder with poor prognosis similar to lung cancer. The pathogenesis of IPF is uncertain, but loss of epithelial cells and fibroblast proliferation are thought
Publikováno v:
Am. J. Physiol. Lung Cell Mol. Physiol. 309, L323-L332 (2015)
During the last decades, the study of cell behavior was largely accomplished in uncoated or extracellular matrix (ECM)-coated plastic dishes. To date, considerable cell biological efforts have tried to model in vitro the natural microenvironment foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0b8427be7c76472bd9bae7f30f7b9a
https://europepmc.org/articles/PMC4538231/
https://europepmc.org/articles/PMC4538231/