Zobrazeno 1 - 3 of 3 pro vyhledávání: '"Sarah V. Morgan"'
1
Proteomic and cellular localisation studies suggest non‐tight junction cytoplasmic and nuclear roles for occludin in astrocytes
Autor: Paul R. Heath, Thomas C. Minshull, Lydia M. Castelli, Simeon R. Mihaylov, Irina Vaquéz-Villaseñor, Julie E. Simpson, Luke Jennings, Claire J. Garwood, Paul G. Ince, Guillaume M. Hautbergue, Sarah V. Morgan, Mark J. Dickman, Stephen B. Wharton
Publikováno v: The European Journal of Neuroscience
Occludin is a component of tight junctions, which are essential structural components of the blood–brain barrier. However, occludin is expressed in cells without tight junctions, implying additional functions. We determined the expression and local
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5556b667ab7bfb8aefd2df7108696d06
http://europepmc.org/articles/PMC6079634
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3
Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors
Autor: Laura E. Ratcliffe, Helen Owens, Paul G. Ince, Claire J. Garwood, Paul R. Heath, Stephen B. Wharton, Irina Vazquez-Villasenor, Sarah V. Morgan, Julie E. Simpson, Ignacio A. Romero
Publikováno v: Molecular Brain
Background The insulin/IGF1 signalling (IIS) pathways are involved in longevity regulation and are dysregulated in neurons in Alzheimer’s disease (AD). We previously showed downregulation in IIS gene expression in astrocytes with AD-neuropathology
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe6c8127130459aeda3d6b7a5f71058
https://pubmed.ncbi.nlm.nih.gov/26297026
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