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Treg-specific ablation of HuR results in systemic autoimmunity associated with decreased TLR4 activation and IL-1β production

Autor: Ulus Atasoy, Fatemeh Fattahi, Jason S Ellis, Sarah Socha, Kristin Bahleda

Publikováno v: The Journal of Immunology. 208:44.11-44.11

The RNA-binding protein HuR (Elavl1) plays a critical role in T cell activation and function by regulating the stability and transport of its mRNA targets. To study the role of HuR in regulatory T cell (Treg) development and function, we generated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2a60e5884d9d7dd610149aaf08362c0
https://doi.org/10.4049/jimmunol.208.supp.44.11

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