Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Sarah Snykers"'
Autor:
Sarah Snykers
Publikováno v:
Cell and Gene Therapy Insights. 6:1755-1764
Publikováno v:
Cell and Gene Therapy Insights. 5:133-140
Autor:
Hans Prenen, Eric Van Cutsem, Panagiota A. Sotiropoulou, Sarah Snykers, Frederic Lehmann, Emilie Cerf, Sébastien Mauen, Sébastien Anguille, Alain Hendlisz, Jeroen Dekervel, Alexandre Michaux, Anne Flament, Caroline Lonez, David E. Gilham
Publikováno v:
Journal of Clinical Oncology. 38:3032-3032
3032 Background: In contrast to autologous CAR-T cell therapies, allogeneic donor-derived CAR-T cells can be banked and used in a timely fashion overcoming the critical time delay of just in time autologous cell manufacture. CYAD-101 is an allogeneic
Autor:
Philip Roelandt, Mustapha Najimi, Jan Best, Leo A. van Grunsven, Feras Al Battah, Konrad L. Streetz, Etienne Sokal, Sarah Snykers, Neil D. Theise, Jie Mei, Albert Geerts, Laurent Dollé, Vera Rogiers, Isabelle Leclercq, Elke Van Rossen, Christophe Empsen, Catherine M. Verfaillie
Publikováno v:
Hepatology
UNLABELLED: The role of progenitor cells in liver repair and fibrosis has been extensively described, but their purification remains a challenge, hampering their characterization and use in regenerative medicine. To address this issue, we developed a
Autor:
Jason Brayer, Marco L. Davila, Sarah Snykers, Tessa Kerre, Panagiota A. Sotiropoulou, Eunice S. Wang, David A. Sallman, Bikash Verma, Frederic Lehmann, Philippe Lewalle, Eytan Breman, Nathalie Braun, Doreen Dekker, Caroline Lonez, Xavier Poiré, Violaine Havelange
Publikováno v:
Blood. 132:902-902
Introduction: CYAD-01 is a chimeric antigen receptor T-cell (CAR-T) product based on the receptor NKG2D with specificity for a broad range of ligands (MICA, MICB and ULBP1-6) expressed on most tumors. In vivo preclinical studies showed long-term anti
Autor:
Jan G. Hengstler, Vera Rogiers, José V. Castell, Tamara Vanhaecke, Bernward Garthoff, Sarah Snykers
Publikováno v:
Vrije Universiteit Brussel
Alternative testing methods have become increasingly important within EU funding policy. The driving force behind this push for alternative testing methods is the urgent need for effective and robust alternative toxicity tests in order to make the to
Publikováno v:
Vrije Universiteit Brussel
Direct communication between cells, mediated by gap junctions, is nowadays considered as an indispensable mechanism in the maintenance of cellular homeostasis. In fact, gap junctional intercellular communication is actively involved in virtually all
Autor:
Jerome Ritz, Sarah Snykers, Sarah Nikiforow, Nikhil C. Munshi, Heather Daley, Matthew Jacobs, Helene Negre, Rachel Allen, Joana M. Murad, Heidi Dipietro, Robert J. Soiffer, Donna Neuberg, Charles L. Sentman, Glenn Dranoff, Randie E White, Frederic Lehmann, Lillian Werner, Robert L. Schlossman, Ilene Galinsky, Susanne H.C. Baumeister, Richard Stone, Adam Schmucker, Lauren Johnston, Sarah Patches, Jake Reder, Terri K. Wade, Kristen Cummings
Publikováno v:
Blood. 128:4052-4052
Introduction: Conventional CAR-T cells express a single chain antibody variable fragment that restricts recognition to one tumor antigen and a limited set of cancers. This study employs a novel CAR fusing full-length human NKG2D with the CD3z signali
Autor:
F. Collignon, J. Goffinet, Jean-François Michiels, José Castillo, Christophe Gumy, Sarah Snykers, Philippe Willemsen, C. Dedry, M. Egloff, Jean-Christophe Drugmand
Publikováno v:
BMC Proceedings
Promethera Biosciences (Mont-St-Guibert, BE) is developing cell therapies to treat several liver genetic metabolic diseases, such as the Crigler-Najjar syndrome. Human heterologous adult liver progenitors cells (HHALPCs) were initially cultivated in
Autor:
Jerome Ritz, Robert J. Soiffer, Charles L. Sentman, Sarah Snykers, Frederic Lehmann, Richard Stone, Ilene Galinsky, Jake Reder, Rachel Allen, Helene Negre, Joana M. Murad, Heather Daley, Susanne H.C. Baumeister, Sarah Nikiforow, Nikhil C. Munshi
Publikováno v:
Journal of Clinical Oncology. 34:TPS3102-TPS3102
TPS3102Background: Canonical CAR-T cell constructs encode a single chain antibody variable fragment, costimulatory domain, and signaling domain of CD3 zeta. This restricts recognition to 1 tumor an...