Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sarah Signor"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 3, p e1011201 (2024)
During the last few centuries D. melanogaster populations were invaded by several transposable elements, the most recent of which was thought to be the P-element between 1950 and 1980. Here we describe a novel TE, which we named Spoink, that has inva
Externí odkaz:
https://doaj.org/article/1b4bd7157aa44143b56fdeda20e6e087
Autor:
Sarah Signor, Jeffrey Vedanayagam, Bernard Y Kim, Filip Wierzbicki, Robert Kofler, Eric C Lai
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010914 (2023)
Suppression of transposable elements (TEs) is paramount to maintain genomic integrity and organismal fitness. In D. melanogaster, the flamenco locus is a master suppressor of TEs, preventing the mobilization of certain endogenous retrovirus-like TEs
Externí odkaz:
https://doaj.org/article/85b67978c56e4aaf99dea3b32a57f25d
Autor:
Sarah Signor
Publikováno v:
Ecology and Evolution, Vol 10, Iss 7, Pp 3402-3412 (2020)
Abstract Transposable elements are abundant, dynamic components of the genome that affect organismal phenotypes and fitness. In Drosophila melanogaster, they have increased in abundance as the species spread out of Africa, and different populations d
Externí odkaz:
https://doaj.org/article/e36353b4078a43ffac97d8d2d73f8eb3
Autor:
Adalena V Nanni, Natalie Martinez, Rita Graze, Alison Morse, Jeremy R B Newman, Vaibhav Jain, Srna Vlaho, Sarah Signor, Sergey V Nuzhdin, Rolf Renne, Lauren M McIntyre
Publikováno v:
Molecular Biology and Evolution. 40
In Drosophila melanogaster and D. simulans head tissue, 60% of orthologous genes show evidence of sex-biased expression in at least one species. Of these, ∼39% (2,192) are conserved in direction. We hypothesize enrichment of open chromatin in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dae04047fae898cf68a9b2cef13ff4e
https://doi.org/10.1093/molbev/msad078
https://doi.org/10.1093/molbev/msad078
Autor:
Adalena V. Nanni, Natalie Martinez, Rita Graze, Alison Morse, Jeremy R. B. Newman, Vaibhav Jain, Srna Vlaho, Sarah Signor, Sergey V. Nuzhdin, Rolf Renne, Lauren M. McIntyre
We propose a new model for the association of chromatin state and sex-bias in expression. We hypothesize enrichment of open chromatin in the sex where we see expression bias (OS) and closed chromatin in the opposite sex (CO). In this study ofD. melan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da2557ab28435aabe3ea77416d2ac575
https://doi.org/10.1101/2023.01.13.523946
https://doi.org/10.1101/2023.01.13.523946
Autor:
Sarah Signor, Jeffrey Vedanayagam, Bernard Y. Kim, Filip Wierzbicki, Robert Kofler, Eric C. Lai
Effective suppression of transposable elements (TEs) is paramount to maintain genomic integrity and organismal fitness. InD. melanogaster,flamencois a master suppressor of TEs, preventing their movement from somatic ovarian support cells to the germl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::208232e183da7c8a101f21c75f7104fa
https://doi.org/10.1101/2022.09.29.510127
https://doi.org/10.1101/2022.09.29.510127
Small RNAs produced from transposable element (TE) rich sections of the genome, termed piRNA clusters, are a crucial component in the genomic defense against selfish DNA. In animals it is thought the invasion of a TE is stopped when a copy of the TE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e4bf77c7cc3f62efc875ed785a0cea
https://doi.org/10.1101/2021.08.20.457083
https://doi.org/10.1101/2021.08.20.457083
Publikováno v:
Journal of insect physiology. 137
Diapause is a complex physiological phenomenon that allows insects to weather stressful environmental conditions. The regulation of diapause is accordingly complex, including signaling pathways that involve both small RNA and mRNA and affect the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405d90871e130f0b791d4289491f0d0c
https://pubmed.ncbi.nlm.nih.gov/35063439
https://pubmed.ncbi.nlm.nih.gov/35063439
Autor:
Sarah, Signor
Publikováno v:
Ecology and Evolution
Transposable elements are abundant, dynamic components of the genome that affect organismal phenotypes and fitness. In Drosophila melanogaster, they have increased in abundance as the species spread out of Africa, and different populations differ in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::563d790176b21330bc996e3703fa6ae8
https://pubmed.ncbi.nlm.nih.gov/32273997
https://pubmed.ncbi.nlm.nih.gov/32273997