Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Sarah Schumann"'
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Akademický článek
Correlation of the absorbed dose to the blood and DNA damage in leukocytes after internal ex-vivo irradiation of blood samples with Ra-224
Autor: Sarah Schumann, Uta Eberlein, Jessica Müller, Harry Scherthan, Michael Lassmann
Publikováno v: EJNMMI Research, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Background Irradiation with α-particles creates densely packed damage tracks along particle trajectories in exposed cells, including complex DNA damage and closely spaced double-strand breaks (DSBs) in hit nuclei. Here, we investigated the
Externí odkaz: https://doaj.org/article/ab423fe72287476aaa592e26534ff25f
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4
Repair of α-particle-induced DNA damage in peripheral blood mononuclear cells after internal ex vivo irradiation with 223Ra
Autor: Lukas Göring, Sarah Schumann, Jessica Müller, Andreas K. Buck, Matthias Port, Michael Lassmann, Harry Scherthan, Uta Eberlein
Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 49:3981-3988
Purpose As α-emitters for radiopharmaceutical therapies are administered systemically by intravenous injection, blood will be irradiated by α-particles that induce clustered DNA double-strand breaks (DSBs). Here, we investigated the induction and r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8137b9c24ec80df38da2231e3713187a
https://doi.org/10.1007/s00259-022-05860-3
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5
DNA damage and repair in peripheral blood mononuclear cells after internal ex vivo irradiation of patient blood with 131I
Autor: KR Pfestroff, Andreas Pfestroff, Andreas K. Buck, S. Schoof, Sarah Schumann, Harry Scherthan, Natalie Hasenauer, Uta Eberlein, Michael Lassmann, Markus Luster, Philipp E. Hartrampf, Matthias Port
Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging
Aim The aim of this study was to provide a systematic approach to characterize DNA damage induction and repair in isolated peripheral blood mononuclear cells (PBMCs) after internal ex vivo irradiation with [131I]NaI. In this approach, we tried to mim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8e0c76f7eb2e1b3cf2955686f5df12
https://doi.org/10.1007/s00259-021-05605-8
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α-Particle-induced DNA damage tracks in peripheral blood mononuclear cells of [\(^{223}\)Ra]RaCl\(_{2}\)-treated prostate cancer patients
Autor: Constantin Lapa, Jessica Müller, Sarah Schumann, Michael Lassmann, Harry Scherthan, Uta Eberlein, Sebastian Serfling
Purpose One therapy option for prostate cancer patients with bone metastases is the use of [223Ra]RaCl2. The α-emitter 223Ra creates DNA damage tracks along α-particle trajectories (α-tracks) in exposed cells that can be revealed by immunofluoresc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0fb7f3f4185bb2afb041757f72ad10
https://opus.bibliothek.uni-wuerzburg.de/files/26546/Schumann_European.pdf
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