Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sarah Schlesinger Frankel"'
Autor:
John R. Mascola, Josephine H. Cox, Merlin L. Robb, Pierre A. Caudrelier, Raphaelle El-Habib, Silvia Ratto-Kim, Beatrice Schuler-Thurner, Wendy B. Bernstein, Jeffrey R. Currier, Michael A. Eller, Mark K. Louder, Deborah L. Birx, Ralph M. Steinman, Bruce L. Levine, Carl H. June, Sarah Schlesinger-Frankel, Mary A. Marovich
Publikováno v:
The Journal of Infectious Diseases. 186:1242-1252
Preclinical data are reported that support a human immunodeficiency virus (HIV) vaccine strategy using recombinant canarypox-HIV vectors (ALVAC-HIV) to load human dendritic cells (DCs) with HIV antigens. Clinical-grade DCs were infected with good man
Autor:
John R. Mascola, Ralph M. Steinman, Karsten Mahnke, William I. Cox, Loreley Villamide, Mary A. Marovich, Erin Mehlhop, Melissa Pope, Frank Isdell, Ralf Ignatius, Sarah Schlesinger Frankel
Publikováno v:
Journal of Virology. 74:11329-11338
Recombinant avipox viruses are being widely evaluated as vaccines. To address how these viruses, which replicate poorly in mammalian cells, might be immunogenic, we studied how canarypox virus (ALVAC) interacts with primate antigen-presenting dendrit
Autor:
Melissa Pope, Ralph M. Steinman, Lei Zhong, Angela Granelli-Piperno, Mark G. Lewis, Ralf Ignatius, Sarah Schlesinger Frankel
Publikováno v:
European Journal of Immunology. 30:3281-3290
To pursue the capacity of monkey dendritic cells (DC) to be modified by adenoviral vectors and present the encoded antigens, we generated DC from blood monocytes and infected them with recombinant adenoviruses encoding GFP reporter and SIVgag or nef
Publikováno v:
Clinical immunology (Orlando, Fla.). 103(3 Pt 1)
Autor:
John R. Mascola, Gerald S. Murphy, Curtis Hayes, Shuenn-Ju Wu, Sarah Schlesinger-Frankel, Mark K. Louder, Mary A. Marovich, Ravithat Putvatana, Deborah L. Birx, Timothy Burgess, Boonrat Tassaneetrithep, Wellington Sun, Michael A. Eller, Geraldine Grouard-Vogel
Publikováno v:
The journal of investigative dermatology. Symposium proceedings. 6(3)
Dengue virus infections are an emerging global threat. Severe dengue infection is manifested as dengue hemorrhagic fever and dengue shock syndrome, both of which can be fatal complications. Factors predisposing to complicated disease and pathogenesis
Autor:
Thomas C. Quinn, Sarah Schlesinger Frankel, Cecil H. Fox, Mary Young, Drew Weissman, Sodsai Tovanabutra, Gerald Willett, Chirasak Khamboonruang, Lertlakana Bhoopat, Maryanne Vahey, Thomas C. VanCott, Sungwal Rugpao, Michael A. Cohn, Kenrad E. Nelson, Sandra Barrick
Publikováno v:
The Journal of infectious diseases. 184(4)
Thai residents have a greater risk of heterosexual transmission of human immunodeficiency virus (HIV) than do US residents. To analyze host factors associated with heterosexual transmission, vaginal epithelial biopsies from HIV-seropositive Thai and
Autor:
Gregory M. Glenn, Sarah Schlesinger Frankel, Andrew D. Montemarano, Carl R. Alving, Xiuru Li, David N. Taylor
Publikováno v:
Nature medicine. 6(12)
Transcutaneous immunization, a topical vaccine application, combines the advantages of needle-free delivery while targeting the immunologically rich milieu of the skin. In animal studies, this simple technique induces robust systemic and mucosal anti
Autor:
John R. Mascola, Mark K. Louder, Curtis G. Hayes, Elena F. Brachtel, Wellington Sun, Gerald S. Murphy, Luis Filgueira, Ravithat Putvatana, Deborah L. Birx, Merlin L. Robb, Mary A. Marovich, Shuenn-Jue L. Wu, Henry K. Wong, Bruce L. Innes, Geraldine Grouard-Vogel, Sarah Schlesinger Frankel, Andrew Blauvelt
Publikováno v:
Nature medicine. 6(7)
Dengue virus (DV), an arthropod-borne flavivirus, causes a febrile illness for which there is no antiviral treatment and no vaccine. Macrophages are important in dengue pathogenesis; however, the initial target cell for DV infection remains unknown.
Autor:
Deborah Hayes, John R. Mascola, Hermann Katinger, Gabriela Stiegler, Mark K. Louder, Christine V. Sapan, Thomas C. VanCott, Merlin L. Robb, Yichen Lu, Deborah L. Birx, Dawn Harris, Mark G. Lewis, Sarah Schlesinger Frankel, Charles R. Brown
Publikováno v:
Journal of virology. 73(5)
The role of antibody in protection against human immunodeficiency virus (HIV-1) has been difficult to study in animal models because most primary HIV-1 strains do not infect nonhuman primates. Using a chimeric simian/human immunodeficiency virus (SHI