Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sarah Sariban-Sohraby"'
Publikováno v:
Journal of Biological Chemistry. 280:24181-24187
Confluent monolayers of epithelial cells grown on nonporous support form fluid-filled hemicysts called domes, which reflect active ion transport across the epithelium. Clara-like H441 lung adenocarcinoma cells grown on glass supports and exposed to 5
Autor:
Andrea Becchetti, Douglas C. Eaton, Sarah Sariban-Sohraby, James D. Stockand, Alexandra E. Kemendy
Publikováno v:
Journal of Biological Chemistry. 275:16550-16559
We used single channel methods on A6 renal cells to study the regulation by methylation reactions of epithelial sodium channels. 3-Deazaadenosine (3-DZA), a methyltransferase blocker, produced a 5-fold decrease in sodium transport and a 6-fold decrea
Autor:
Robert S. Edinger, Douglas C. Eaton, Nabil Al-Baldawi, James D. Stockand, Sarah Sariban-Sohraby, Otor Al-Khalili, John P. Johnson
Publikováno v:
Journal of Biological Chemistry. 274:26912-26916
The Xenopus laevis distal tubule epithelial cell line A6 was used as a model epithelia to study the role of isoprenylcysteine-O-carboxyl methyltransferase (pcMTase) in aldosterone-mediated stimulation of Na(+) transport. Polyclonal antibodies raised
Publikováno v:
American Journal of Physiology-Renal Physiology. 276:F10-F17
The GTP-binding proteins from cultured A6 epithelia were examined in isolated membrane preparations. Binding of [35S]GTPγS revealed a class of binding sites with an apparent Kdvalue of 100 nM and a Bmaxof 220 pmol/mg protein. Short-term aldosterone
Publikováno v:
Kidney International. 48:965-969
A number of recent reviews have dealt extensively with the characteristics of epithelial Na + channels and their classification according to level of conductance, selectivity for sodium, and sensitivity to amiloride and hormones [1 to 6, this issue].
Publikováno v:
American Journal of Physiology-Cell Physiology. 263:C1111-C1117
The apical membrane of high electrical resistance epithelia, which is selectively permeable to Na+, plays an essential role in the maintenance of salt balance. Na+ entry from the apical fluid into the cells is mediated by amiloride-blockable Na(+)-sp
Autor:
Ahmed Chraibi, Renauld Stéphane, Vadim Shlyonsky, Arnaud Goolaerts, Jean-Francois Pittet, Jérémie Roux, Frédérique Mies, Michael T. Ganter, Sarah Sariban-Sohraby, Robert Naeije, Marybeth Howard, Michael A. Matthay
Publikováno v:
American journal of respiratory cell and molecular biology. 43(1)
Hypoxia and epithelial stretch that are commonly observed in patients with acute lung injury have been shown to promote the release of serotonin (5-hydroxytryptamine, 5-HT) in vitro. However, whether 5-HT contributes to the decrease of alveolar epith
Publikováno v:
The Journal of biological chemistry. 282(25)
Essential polyunsatured fatty acids have been shown to modulate enzymes, channels and transporters, to interact with lipid bilayers and to affect metabolic pathways. We have previously shown that eicosapentanoic acid (EPA, C20:5, n-3) activates epith
Publikováno v:
The FASEB Journal. 20
Publikováno v:
The FASEB Journal. 20