Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sarah S. Gallagher"'
Autor:
Linda K. Teuschler, Glenn Rice, George Bollweg, Lawrence Martin, Sarah S. Gallagher, Louis Scarano
Publikováno v:
Chemosphere. 120:697-705
Cumulative risk assessments (CRAs) examine potential risks posed by exposure to multiple and sometimes disparate environmental stressors. CRAs are more resource intensive than single chemical assessments, and pose additional challenges and sources of
Autor:
Jeff Gelles, Virginia W. Cornish, Nicholas Ramirez, Aaron A. Hoskins, Eric G. Anderson, Sarah S. Gallagher, Richard Wombacher, Daniel J. Crawford, Larry J. Friedman, Melissa J. Moore
Publikováno v:
Science. 331:1289-1295
The spliceosome is the complex macromolecular machine responsible for removing introns from precursors to messenger RNAs (pre-mRNAs). We combined yeast genetic engineering, chemical biology, and multiwavelength fluorescence microscopy to follow assem
Publikováno v:
ACS Chemical Biology. 4:547-556
Chemical tags for live cell imaging are emerging as viable alternatives to the fluorescent proteins for labeling proteins with small molecule probes. Among reported chemical tags, trimethoprim (TMP)-tag stands out for having sufficient cell permeabil
Autor:
John E. Baldwin, David C. Powers, Sarah S. Gallagher, Lynne A. Mccullough, Phyllis A. Leber, Andrew T. Higgs
Publikováno v:
The Journal of Organic Chemistry. 72:187-194
At 300 degrees C, bicyclo[4.2.0]oct-2-ene (1) isomerizes to bicyclo[2.2.2]oct-2-ene (2) via a formal [1,3] sigmatropic carbon migration. Deuterium labels at C7 and C8 were employed to probe for two-centered stereomutation resulting from C1-C6 cleavag
Autor:
Darcy S. Peterka, Chaoran Jing, Mariam M. Konaté, Rafael Yuste, Virginia W. Cornish, Sarah S. Gallagher, Richard Wombacher, Laura J. Kaufman
Publikováno v:
Chembiochem
Two-photon excitation results from the near simultaneous absorption of two relatively low-energy photons by a fluorophore, causing a transition to an excited state with an energy difference close to that of the combined two photons (Figure 1 A).1 For
Publikováno v:
Analytical Biochemistry. 363:160-162
The yeast three-hybrid assay is an important tool for the detection of protein-ligand interactions in vivo and has recently been used successfully for the discovery of novel drug targets and the directed evolution of enzymes[1–6]. Schreiber and co-
Publikováno v:
Journal of the American Chemical Society. 134(33)
Chemical tags are now viable alternatives to fluorescent proteins for labeling proteins in living cells with organic fluorophores that have improved brightness and other specialized properties. Recently, we successfully rendered our TMP-tag covalent
Autor:
and Anuradha S. Raghavan, Rajesh Shukla, Sarah S. Gallagher, Phyllis A. Leber, John E. Baldwin
Publikováno v:
The Journal of organic chemistry. 69(21)
The thermal conversion of cis-bicyclo[4.2.0]oct-7-ene to cis,cis-1,3-cyclooctadiene might involve a direct disrotatory ring opening, or it might possibly take place by way of cis,trans-1,3-cyclooctadiene. This cis,trans-diene might possibly form the
Publikováno v:
Organic letters. 6(9)
[reaction: see text] The ratio of observed rate constants, k/k', for thermal isomerizations of cis-bicyclo[4.2.0]oct-7-ene and its 2,2,5,5-d(4) analogue to cis,cis-1,3-cyclooctadienes at 250 degrees C is 1.17, indicative of a secondary, not a primary
Autor:
Daniel J. Crawford, Aaron A. Hoskins, Richard Wombacher, Larry J. Friedman, Virginia W. Cornish, Nicholas Ramirez, Jeff Gelles, Melissa J. Moore, Sarah S. Gallagher, Eric G. Anderson
Publikováno v:
ResearcherID
Spliceosome assembly is a highly dynamic and complex process involving the addition of 5 snRNAs and >100 proteins to a pre-mRNA transcript. This process has largely been analyzed by discontinuous assays that provide limited kinetic information. By co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f7bea8db296b1222a8544b8b65a9ee
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000306288602037&KeyUID=WOS:000306288602037
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000306288602037&KeyUID=WOS:000306288602037