Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sarah S K Yue"'
Autor:
Bernard C. H. Lee, Philip S. Robinson, Tim H. H. Coorens, Helen H. N. Yan, Sigurgeir Olafsson, Henry Lee-Six, Mathijs A. Sanders, Hoi Cheong Siu, James Hewinson, Sarah S. K. Yue, Wai Yin Tsui, Annie S. Y. Chan, Anthony K. W. Chan, Siu Lun Ho, Peter J. Campbell, Inigo Martincorena, Simon J. A. Buczacki, Siu Tsan Yuen, Suet Yi Leung, Michael R. Stratton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
It is unclear whether somatic mutation rates are elevated in Lynch Syndrome (LS), which is the most common cause of hereditary colorectal cancer. Here, the authors use whole-genome sequencing and organoid cultures to show that normal tissues in LS pa
Externí odkaz:
https://doaj.org/article/9ffe8e161f6f47b6ae292571819e0a78
Autor:
Hoi Cheong Siu, April S. Chan, Anthony K W Chan, Jason W. H. Wong, Alice H Y Man, Wai Yin Tsui, Annie S Y Chan, Ho Sang Hui, Bernard C H Lee, Hans Clevers, D Chan, Arthur Kwok Leung Cheung, Siu Lun Ho, Helen H.N. Yan, Sarah S K Yue, Oswens Siu-Hung Lo, Yang Gao, Suet Yi Leung, Wai Lun Law, Siu Tsan Yuen
Publikováno v:
Gut, 69(12), 2165-2179. BMJ Publishing Group
ObjectiveSporadic early-onset colorectal cancer (EOCRC) has bad prognosis, yet is poorly represented by cell line models. We examine the key mutational and transcriptomic alterations in an organoid biobank enriched in EOCRCs.DesignWe established pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f088e70976d8619feae560c7711a9e
https://doi.org/10.1136/gutjnl-2019-320019
https://doi.org/10.1136/gutjnl-2019-320019
Autor:
Yin Tong, Priscilla S W Cheng, Chung Sze Or, Sarah S K Yue, Hoi Cheong Siu, Siu Lun Ho, Simon Y K Law, Wai Yin Tsui, Dessy Chan, Stephanie Ma, Siu Po Lee, Annie S Y Chan, April S Chan, Shui Wa Yun, Ho Sang Hui, Siu Tsan Yuen, Suet Yi Leung, Helen H N Yan
Publikováno v:
Gut. 72(2)
ObjectiveCell-cell (CC) and cell-matrix (CM) adhesions are essential for epithelial cell survival, yet dissociation-induced apoptosis is frequently circumvented in malignant cells.DesignWe explored CC and CM dependence in 58 gastric cancer (GC) organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2f0a7f7354ec79b1de78ffc132ab71
https://pubmed.ncbi.nlm.nih.gov/35705367
https://pubmed.ncbi.nlm.nih.gov/35705367
Autor:
Yin Tong, Priscilla S. W. Cheng, Chung Sze Or, Sarah S. K. Yue, Hoi Cheong Siu, Siu Lun Ho, Simon Y. K. Law, Wai Yin Tsui, Dessy Chan, Stephanie Ma, Siu Po Lee, Annie S. Y. Chan, April S. Chan, Shui Wa Yun, Ho Sang Hui, Siu Tsan Yuen, Suet Yi Leung, Helen H. N. Yan
Publikováno v:
Gut; Feb2023, Vol. 72 Issue 2, p240-255, 14p
Autor:
Jeffrey C W Lai, Suet Yi Leung, Helen H.N. Yan, Siu Lun Ho, Janet F. Y. Lee, Alice H Y Man, Wai Yin Tsui, Annie S Y Chan, Siu Tsan Yuen, Bernard C H Lee, Wai K. Leung, Wai Lun Law, Hans Clevers, Sarah S K Yue, Anthony K W Chan
Publikováno v:
Gut. BMJ Publishing Group
OBJECTIVE: Serrated polyps (hyperplastic polyps, sessile or traditional serrated adenomas), which can arise in a sporadic or polyposis setting, predispose to colorectal cancer (CRC), especially those with microsatellite instability (MSI) due to MLH1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c66b88971dcf1658a9beec807a24e76
https://doi.org/10.1136/gutjnl-2016-311849
https://doi.org/10.1136/gutjnl-2016-311849