Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sarah Roord"'
Autor:
Theo van den Broek, Evelien Zonneveld-Huijssoon, Femke van Wijk, Nico M Wulffraat, Femke Broere, Berent J. Prakken, Sarah Roord, Tibor T. Glant, Henk Rozemuller, Eveline M. Delemarre, Wilco de Jager, Anton C.M. Martens
Publikováno v:
Arthritis & Rheumatology. 66:350-356
Objective Autologous stem cell transplantation (ASCT) induces long-term drug-free disease remission in patients with juvenile idiopathic arthritis. This study was undertaken to further unravel the immunologic mechanisms underlying ASCT by using a mou
Autor:
Mark A. Klein, Wietse Kuis, Stephen M. Anderton, Evelien Zonneveld-Huijssoon, Wilco de Jager, Berent J. Prakken, Salvatore Albani, Sarah Roord, Femke van Wijk
Publikováno v:
Annals of the Rheumatic Diseases. 70:2199-2206
Objectives Mucosal immune therapy with disease-inducing antigens is an effective way to prevent experimental arthritis, but in humans these antigens are unknown. In juvenile idiopathic arthritis, however, T cell recognition of a so-called bystander a
Publikováno v:
Future Rheumatology. 1:649-655
Sarah TA Roord, Berent J Prakken & Salvatore Albani † †Author for correspondence University of California, San Diego, Departments of Medicine & Pediatrics, 9500 Gilman Drive, La Jolla, CA 92093-0731, USA Tel.: +1 858 534 0394; Fax: +1 858 822 566
Autor:
Diane Amox, Salvatore Albani, Rosario Billetta, Sarah Roord, Berent J. Prakken, Francesca Giannoni, Dustan Bonnin, Rodrigo Samodal, Margherita Massa, John Scavulli, Ismé M. de Kleer, Paola Lanza, Gisella Puga Yung, Tho Le, Charles C. Berry
Publikováno v:
Proceedings of the National Academy of Sciences. 101:4228-4233
Modulation of epitope-specific immune responses would represent a major addition to available therapeutic options for many autoimmune diseases. The objective of this work was to induce immune deviation by mucosal peptide-specific immunotherapy in rhe
Publikováno v:
Inflammation Research. 52:443-451
Rheumatoid arthritis (RA) is an inflammatory disease that primarily involves the joints and has a worldwide prevalence of about one percent, with a female to male ratio of 3:1. This chapter summarizes some of the recent progress in molecular immunolo
Autor:
Salvatore Albani, Arash Ronaghy, Marca H. M. Wauben, Sarah Roord, Willem van Eden, Berent J. Prakken
Publikováno v:
Springer Seminars in Immunopathology. 25:47-63
Heat shock proteins (hsp) are highly conserved, immune-dominant microbial proteins, whose expression is increased at sites of inflammation. In the experimental model of adjuvant arthritis (AA) immune responses to hsp determine the outcome of disease.
Autor:
Berent J. Prakken, Willem van Eden, J. P. A. Wagenaar, Peter J.S. van Kooten, Sarah Roord, Salvatore Albani, Marca H. M. Wauben
Publikováno v:
Arthritis & Rheumatism. 46:1937-1946
Objective To prevent and treat experimental arthritis via nasal administration of an altered peptide ligand (APL) from the major arthritogenic epitope in adjuvant-induced arthritis (AIA) and to explore the mechanisms involved. Methods Peptides were a
Autor:
David L. Boyle, Dennis A. Carson, Eyal Raz, Gary S. Firestein, Berent J. Prakken, Nathan J. Zvailfler, Kenji Takabayashi, Arash Ronaghy, Salvatore Albani, Sarah Roord
Publikováno v:
The Journal of Immunology. 168:51-56
Bacterial DNA is enriched in unmethylated CpG motifs that have been shown to activate the innate immune system. These immunostimulatory DNA sequences (ISS) induce inflammation when injected directly into joints. However, the role of bacterial DNA in
Publikováno v:
Current stem cell researchtherapy. 6(1)
Juvenile idiopathic arthritis (JIA) is one of the most frequent autoimmune diseases in childhood and is characterized by chronic inflammation of the synovial fluid in joints. Several drugs are available for the treatment of JIA, including various bio
Publikováno v:
Autoimmunity. 41(8)
Since a decade autologous stem cell transplantation (ASCT) is successfully performed to treat patients with severe autoimmune disease. However, the mechanism of action of this intervention remains largely unknown. Scarce data from animal studies and