Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sarah Rivas"'
Autor:
Ashish H. Shah, Vaidya Govindarajan, Tara T. Doucet-O’Hare, Sarah Rivas, Leo Ampie, Catherine DeMarino, Yeshavanth Kumar Banasavadi-Siddegowda, Yong Zhang, Kory R. Johnson, Fahad Almsned, Mark R. Gilbert, John D. Heiss, Avindra Nath
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Comprising approximately 8% of our genome, Human Endogenous RetroViruses (HERVs) represent a class of germline retroviral infections that are regulated through epigenetic modifications. In cancer cells, which often have epigenetic dysregulat
Externí odkaz:
https://doaj.org/article/881d38f1fc7640198c8a35126450c536
Autor:
Vaidya Govindarajan, Ashish H. Shah, Alexis A. Morell, Veronica Borowy, Shreya M. Ingle, Mynor J. Mendez Valdez, Sarah Rivas, Daniel G. Eichberg, Evan Luther, Victor Lu, John Heiss, Ricardo J. Komotar, Allan D. Levi
Publikováno v:
World Neurosurgery.
Autor:
Ashish Harish Shah, Sarah Rivas, Tara Doucet-Ohare, Vaidya Govindarajan, Catherine DeMarino, Leonel Ampie, Yeshavanath Banasavadi-Siddegowda, Dragan Maric, Rob Suter, Myoung-hwa Lee, Kareem A. Zaghloul, Stuart Walbridge, Marta Garcia-Montojo, Joe Steiner, Kory Johnson, Mark R. Gilbert, John D. Heiss, Avindra Nath
Publikováno v:
Neurosurgery. 69:66-67
Autor:
Yeshavanth Kumar Banasavadi-Siddegowda, Sriya Namagiri, Yoshihiro Otani, Hannah Sur, Sarah Rivas, Jean-Paul Bryant, Allison Shellbourn, Mitchell Rock, Ashis Chowdhury, Cole T Lewis, Toshihiko Shimizu, Stuart Walbridge, Sivarajan Kumarasamy, Ashish H Shah, Tae Jin Lee, Dragan Maric, Yuanqing Yan, Ji Young Yoo, Sangamesh G Kumbar, John D Heiss, Balveen Kaur
Publikováno v:
Neurooncol Adv
Background The prognosis of glioblastoma (GBM) remains dismal because therapeutic approaches have limited effectiveness. A new targeted treatment using MEK inhibitors, including trametinib, has been proposed to improve GBM therapy. Trametinib had a p
Autor:
Sarah Rivas, Kimberly Rivera-Caraballo, Sara Murphy, Yoshihiro Otani, Allison Shelbourn, Leo Ampie, Dragan Maric, Stuart Walbridge, Ashish Shah, Yuanqing Yan, Ji young Yoo, John Heiss, Balveen Kaur, Yeshavanath Banasavadi-Siddegowda
Publikováno v:
Neuro-Oncology. 24:vii226-vii227
INTRODUCTION The median survival of Glioblastoma (GBM) patients is less than two years with the standard of care of maximal surgical resection, radiation, and temozolomide (TMZ) chemotherapy. Protein Arginine Methyltransferase 5 (PRMT5), which regula
Publikováno v:
Neuro-Oncology. 24:vii216-vii217
Glioblastoma (GBM) is a WHO grade IV glioma whose heterogeneous nature and stem-like features contribute to resistance to conventional chemotherapeutics. Previously, antiretrovirals have been proposed as anti-neoplastic agents, but their clinical eff
Autor:
Vaidya Govindarajan, Ashish H. Shah, Long Di, Sarah Rivas, Robert K. Suter, Daniel G. Eichberg, Evan Luther, Victor Lu, Alexis A. Morell, Michael E. Ivan, Ricardo J. Komotar, Nagi Ayad, Macarena De La Fuente
Publikováno v:
World Neurosurg
BACKGROUND: Isocitrate dehydrogenase (IDH) mutations are present in 70% of World Health Organization grade II and III gliomas. IDH mutation induces accumulation of the oncometabolite 2-hydroxyglutarate. Therefore, therapies targeting reversal of epig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e34252addc395e2364af3636352299
https://europepmc.org/articles/PMC9177782/
https://europepmc.org/articles/PMC9177782/
Autor:
Ashish H. Shah, Vaidya Govindarajan, Tara T. Doucet-O’Hare, Sarah Rivas, Leo Ampie, Catherine DeMarino, Yeshavanth Kumar Banasavadi-Siddegowda, Yong Zhang, Kory R. Johnson, Fahad Almsned, Mark R. Gilbert, John D. Heiss, Avindra Nath
Publikováno v:
Scientific reports. 12(1)
Comprising approximately 8% of our genome, Human Endogenous RetroViruses (HERVs) represent a class of germline retroviral infections that are regulated through epigenetic modifications. In cancer cells, which often have epigenetic dysregulation, HERV
Autor:
Ashish Shah, Sarah Rivas, Tara Doucet-Ohare, Vaidya Govindarajan, Catherine DeMarino, Leo Ampie, Yeshavanath Banasavadi-Siddegowda, Dragan Maric, Marta Garcia-Montojo, Rob Suter, Myoung-Hwa Lee, Stuart Walbridge, Kareem Zaghloul, Joseph Steiner, Kory Johnson, Mark Gilbert, John Heiss, Avindra Nath
Publikováno v:
Neuro-Oncology. 24:vii32-vii32
Human Endogenous Retrovirus (HERV) are ancestral viral relics that comprise nearly 8% of the human genome. Although silenced in normal tissues, the most recently integrated provirus HERV-K (HML-2) can be pathologically reactivated in certain cancers.
Autor:
Ashish Shah, Vaidya Govindarajan, Tara Doucet-O'Hare, Sarah Rivas, Leo Ampie, Catherine DeMarino, Yeshavanath Banasavadi-Siddegowda, Yong Zhang, Kory Johnson, Fahad Almsned, Mark Gilbert, John Heiss, Avindra Nath
Publikováno v:
Neuro-Oncology. 24:vii123-vii123
INTRODUCTION Comprising approximately 8% of our genome, Human Endogenous RetroViruses (HERVs) represent a class of germline retroviral infections that are regulated through epigenetic modifications. In cancer cells, which often have epigenetic dysreg