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Figure S1 from KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells

Autor: Richard Gedrich, Theresa M. LaVallee, Gerald McMahon, Andrew J. Garton, Lori Lopresti-Morrow, Linda Crew, Krista La Perle, Gerald Post, Sarah Rippy, Heather L. Gardner, Cheryl A. London

Serum KTN0158 concentration over time

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2cb449b9959ba6fe9bf6b2fea2e4da
https://doi.org/10.1158/1078-0432.22467360

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Data from KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells

Autor: Richard Gedrich, Theresa M. LaVallee, Gerald McMahon, Andrew J. Garton, Lori Lopresti-Morrow, Linda Crew, Krista La Perle, Gerald Post, Sarah Rippy, Heather L. Gardner, Cheryl A. London

Purpose: KTN0158 is a novel anti-KIT antibody that potently inhibits wild-type and mutant KIT. This study evaluated the safety, biologic activity, and pharmacokinetic/pharmacodynamics profile of KTN0158 in dogs with spontaneous mast cell tumors (MCT)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699154d93dde439561efde9489060fb3
https://doi.org/10.1158/1078-0432.c.6526620

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Tables S1 and S2 from KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells

Autor: Richard Gedrich, Theresa M. LaVallee, Gerald McMahon, Andrew J. Garton, Lori Lopresti-Morrow, Linda Crew, Krista La Perle, Gerald Post, Sarah Rippy, Heather L. Gardner, Cheryl A. London

Table S1: KTN0158 Dosing Cohorts Table S2: Summary of Anti-KTN0158 Antibody Titers in Dogs with Mast Cell Tumors Following KTN0158 Treatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079e40c819885c8b4c21d2718002b16d
https://doi.org/10.1158/1078-0432.22467354.v1

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London et al_Supplementary Methods from KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells

Autor: Richard Gedrich, Theresa M. LaVallee, Gerald McMahon, Andrew J. Garton, Lori Lopresti-Morrow, Linda Crew, Krista La Perle, Gerald Post, Sarah Rippy, Heather L. Gardner, Cheryl A. London

Supplementary Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4678161d8038ea81c957cbc31b068b10
https://doi.org/10.1158/1078-0432.22467357

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Spectrum Hall of Shame: The Worst (and Best) Radio Policy Decisions

Autor: Allen Magnusson, Sarah Rippy

Publikováno v: SSRN Electronic Journal.

The Silicon Flatirons Center for Law, Technology, and Entrepreneurship held the Spectrum Hall of Shame: The Worst (and Best) Radio Policy Decisions conference on September 6, 2018. In an era of rapid technological development and spectrum scarcity, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::070398f958bd9b8157c68fe91fe21d78
https://doi.org/10.2139/ssrn.3301333

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