Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah Reime"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 52, Iss , Pp 100999- (2024)
In many tumors pronounced extracellular acidosis resulting from glycolytic metabolism is found. Since several environmental stress factors affect the mitochondrial activity the aim of the study was to analyze the impact of acidosis on cellular oxygen
Externí odkaz:
https://doaj.org/article/c10d0f4935e9496e9f0f67a6f8f4ede8
Autor:
Mandy Rauschner, Thea Hüsing, Luisa Lange, Kristin Jarosik, Sarah Reime, Anne Riemann, Oliver Thews
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1275-1288 (2021)
Background: The acidic extracellular environment of tumors has been shown to affect the malignant progression of tumor cells by modulating proliferation, cell death or metastatic potential. The aim of the study was to analyze whether acidosis-depende
Externí odkaz:
https://doaj.org/article/1c3ccacfdc1144ccb19cd56e2d4a8f81
Autor:
Mandy Rauschner, Luisa Lange, Thea Hüsing, Sarah Reime, Alexander Nolze, Marcel Maschek, Oliver Thews, Anne Riemann
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background The low extracellular pH (pHe) of tumors resulting from glycolytic metabolism is a stress factor for the cells independent from concomitant hypoxia. The aim of the study was to analyze the impact of acidic pHe on gene expression o
Externí odkaz:
https://doaj.org/article/3e829c4494cc4738943f649920ff207c
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 5, Pp 450-458 (2019)
Epithelial-to-mesenchymal transition (EMT) is an important process of tumor progression associated with increased metastatic potential. EMT can be activated by external triggers such as cytokines or metabolic parameters (e.g. hypoxia). Since extracel
Externí odkaz:
https://doaj.org/article/915c94d1d17b43eba6bdd5a2d36bebe6
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 12, Pp 1033-1042 (2017)
Inflammatory mediators produced by the tumor cells are of importance for immune response but also for malignant progression. The aim of the study was to analyze the expression of monocyte chemoattractant protein-1, interleukin-6 (IL-6), tumor necrosi
Externí odkaz:
https://doaj.org/article/c32aa4cfb7c94668a0cbb98efc45c8d3
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1862:72-81
Inflammation, ischemia or the microenvironment of solid tumors is often accompanied by a reduction of extracellular pH (acidosis) that stresses the cells and acts on cellular signaling and transcription. The effect of acidosis on the expression of va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fc980571c5af065b25bf6595bd439c
https://doi.org/10.1016/j.bbadis.2015.10.017
https://doi.org/10.1016/j.bbadis.2015.10.017
Publikováno v:
Frontiers in Psychology, Vol 10 (2019)
There is evidence that children begin to understand negation early in the preschool years, but children’s processing of negation is not well understood. We examined children’s processing of denial negation using a variant of the visual world para
Externí odkaz:
https://doaj.org/article/1c67aa267059474bad0cf246b20c2abe
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213373 (2019)
There is widespread concern over the health risks and healthcare costs from potentially inappropriate high-cost imaging. As a result, the Centers for Medicare and Medicaid Services (CMS) will soon require high-cost imaging orders to be accompanied by
Externí odkaz:
https://doaj.org/article/301583c8af92479397aa73da5f54198d