Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sarah R. Nelson"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 70:378-387
An assay using ultrahigh pressure liquid chromatography and mass spectrometry detection was developed and validated for measurement of the HIV integrase inhibitor raltegravir (MK-0518) in human cell extracts. The assay is designed to utilize 200 µl
Autor:
Jayawant N. Mandrekar, Tara M. Gerads, Jordan L. Bendel, Jeffrey J. Germer, Craig A. Dolenc, Joseph D. Yao, Sarah R. Nelson, P. Shawn Mitchell, Amanda L. Masters
Publikováno v:
Journal of Clinical Microbiology. 45:3101-3104
The COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, version 1.5 (CAP/CA), and the COBAS AMPLICOR HIV-1 MONITOR Test, version 1.5, were compared. CAP/CA reduced and consolidated labor while modestly increasing assay throughput without increased fai
Measurement of plasma and intracellular concentrations of raltegravir in patients with HIV infection
Autor:
Sarah R. Nelson, Susan Swindells, Uriel Sandkovsky, Brian L. Robbins, Courtney V. Fletcher, Edward P. Acosta
Publikováno v:
AIDS (London, England). 26(17)
Paired plasma and intracellular samples were obtained from 12 HIV-infected adults taking raltegravir twice daily (b.i.d.), and after switching to once daily. With b.i.d. dosing, no plasma trough concentrations were below the IC95, in contrast to 33%
Autor:
Brian L. Robbins, Susan Swindells, Trevor C. Van Schooneveld, Courtney V. Fletcher, Sarah R. Nelson, Ryan Moore
Current procedures for obtaining and measuring plasma concentrations of HIV protease inhibitors (PIs) are technically challenging. Dried blood spot (DBS) assays offer a way to overcome many of the obstacles. We sought to develop a DBS assay for quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86622a72b6943c701a996ca96dd40daa
https://europepmc.org/articles/PMC2944558/
https://europepmc.org/articles/PMC2944558/