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pro vyhledávání: '"Sarah R. McShane"'
Autor:
Jian Jin, Matthew R. Redinbo, Madhukumar Venkatesh, Libusha Kelly, Sarah R. McShane, Makani Dollinger, Rachel D. Cohen, Kristen A. Biernat, Stephen V. Frye, Charles Pepe-Ranney, Esteban Figueroa, James D. Ingle, Sara O'Neal, S.J. Pellock, Rebecca M. Pollet, Sara J. Robinson, Adam B. Roberts, Sridhar Mani, Leah Guthrie, Bret D. Wallace, William C. Zamboni
Publikováno v:
Chemistry & Biology. (9):1238-1249
SummaryThe selective inhibition of bacterial β-glucuronidases was recently shown to alleviate drug-induced gastrointestinal toxicity in mice, including the damage caused by the widely used anticancer drug irinotecan. Here, we report crystal structur