Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sarah R. Breevoort"'
Publikováno v:
Current Physical Medicine and Rehabilitation Reports. 8:217-228
The purpose of this narrative review was to highlight rehabilitation-relevant aspects of cancer treatment and primarily musculoskeletal impairments and rehabilitation interventions among women with breast and gynecologic cancers. For breast cancer, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::381bb244b1ad642fa3ad1aa0ad44a962
https://doi.org/10.1007/s40141-020-00261-9
https://doi.org/10.1007/s40141-020-00261-9
Autor:
Ira G. Schulman, Kathryn E. Marqueen, Norbert Leitinger, Renata Polanowska-Grabowska, Rachael Griffiths, Sarah R. Breevoort, Jerry Angdisen, Samantha E. Adamson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:1020-1029
Objective— Inflammatory macrophages promote the development of atherosclerosis. We have identified the adaptor protein Dab2 (disabled homolog 2) as a regulator of phenotypic polarization in macrophages. The absence of Dab2 in myeloid cells promotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11f91360ec8efd8a067299b78add8b1a
https://doi.org/10.1161/atvbaha.117.310467
https://doi.org/10.1161/atvbaha.117.310467
Autor:
Md. Torikul Islam, Daniel R. Machin, Anthony J. Donato, Elizabeth I. Nielson, Yu Liu, Parker S. Dobson, Antonio J. Meza, Jessica R Durrant, Lisa A. Lesniewski, Sarah R. Breevoort, Ashley E. Walker
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Atherogenic remodeling often occurs at arterial locations with disturbed blood flow (i.e., low or oscillatory) and both aging and western diet (WD) increase the likelihood for pro-atherogenic remodeling. However, it is unknown if old age and/or a WD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d46540057eae96792c1210cdb2abfa
https://doi.org/10.1038/s41598-019-39466-x
https://doi.org/10.1038/s41598-019-39466-x
Autor:
Anthony J. Donato, R. Garrett Morgan, Stephen J. Ives, Sugata Hazra, Sarah R. Breevoort, Russell S. Richardson, Grant D. Henson, Lisa A. Lesniewski
Publikováno v:
Experimental Gerontology. 83:165-170
MicroRNAs (miRs) are small non-coding RNAs that are important regulators of aging and cardiovascular diseases. MiR-92a is important in developmental vascular growth and tumorigenesis and two of its putative targets, tumor necrosis factor alpha recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c4b4ecf118e2a84576ac376a43e7e7
https://doi.org/10.1016/j.exger.2016.08.007
https://doi.org/10.1016/j.exger.2016.08.007
Autor:
David J. Mangelsdorf, Yuan Zhang, Sarah R. Breevoort, Daniel R. Schmidt, Steven A. Kliewer, Jerry Angdisen, Sam R. Holmstrom, Ira G. Schulman, Mingui Fu
Publikováno v:
Journal of Clinical Investigation. 122:1688-1699
Liver X receptors (LXRα and LXRβ) are important regulators of cholesterol and lipid metabolism, and their activation has been shown to inhibit cardiovascular disease and reduce atherosclerosis in animal models. Small molecule agonists of LXR activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbb7bfca06f7f91e15568f4ed2d6634
https://doi.org/10.1172/jci59817
https://doi.org/10.1172/jci59817
Autor:
Sarah R. Breevoort, David Z. Mokry, Timothy M. Dore, Walter K. Schmidt, Stephen B. Porter, Emily R. Hildebrandt
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1773(6):853-862
The CaaX proteases Rce1p and Ste24p can independently promote a proteolytic step required for the maturation of certain isoprenylated proteins. Although functionally related, Rce1p and Ste24p are unrelated in primary sequence. They have distinct enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351eef78eee0e60ee1d5826dfd28c9ec
Autor:
Dean Y. Li, Lisa A. Lesniewski, Sarah R. Breevoort, Grant D. Henson, Kelly D. Reihl, Christopher C. Gibson, Anthony J. Donato
Publikováno v:
The FASEB Journal. 29
Adipose tissue (AT) function is an important determinant of metabolic homeostasis and healthy AT requires appropriate function of its arterial endothelium to regulate tissue blood flow and limit in...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::702357af796477d0cc6fc33e58559e6f
https://doi.org/10.1096/fasebj.29.1_supplement.802.1
https://doi.org/10.1096/fasebj.29.1_supplement.802.1
Objective— The ability of high-density lipoprotein (HDL) particles to accept cholesterol from peripheral cells, such as lipid-laden macrophages, and to transport cholesterol to the liver for catabolism and excretion in a process termed reverse chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c0d158606bb7b178043d617a12b3fe
https://europepmc.org/articles/PMC4107336/
https://europepmc.org/articles/PMC4107336/
Autor:
Emily R. Hildebrandt, Ned W. Hembree, James P. MacNamara, Adam C. Rea, Stephen B. Porter, Duncan E. McLain, Timothy M. Dore, Walter K. Schmidt, Anne Marie R. Dechert, Sarah R. Breevoort
Publikováno v:
Bioorganicmedicinal chemistry. 18(17)
Dipeptidyl (acyloxy)methyl ketones (AOMKs) have been identified as mechanism-based inhibitors of certain cysteine proteases. These compounds are also inhibitors of the integral membrane proteins Rce1p and Ste24p, which are proteases that independentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db35cfa24a719d52642ce0c2e573bf4f
https://pubmed.ncbi.nlm.nih.gov/20696584
https://pubmed.ncbi.nlm.nih.gov/20696584
Autor:
Amanda J. Castleberry, Ranjith K. Krishnankutty, Sarah R. Breevoort, Sayali S. Kukday, Walter K. Schmidt
Publikováno v:
Yeast (Chichester, England). 26(8)
The CaaX motif directs C-terminal protein modifications that include isoprenylation, proteolysis and carboxylmethylation. Proteolysis is generally believed to require either Rce1p or Ste24p. While investigating the substrate specificity of these prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df0381b52bc174268d31ee016870f9d
https://pubmed.ncbi.nlm.nih.gov/19504624
https://pubmed.ncbi.nlm.nih.gov/19504624