Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sarah R Herlofsen"'
Autor:
Amilton M Fernandes, Sarah R Herlofsen, Tommy A Karlsen, Axel M Küchler, Yngvar Fløisand, Jan E Brinchmann
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62994 (2013)
Lesions of hyaline cartilage do not heal spontaneously, and represent a therapeutic challenge. In vitro engineering of articular cartilage using cells and biomaterials may prove to be the best solution. Patients with osteoarthritis (OA) may require t
Externí odkaz:
https://doaj.org/article/f3e5029ee0bf4c3fb06385e82c66b014
Publikováno v:
Tissue Engineering Part A. 17:1003-1013
We have used a disc-shaped self-gelling alginate hydrogel as a scaffold for in vitro chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells. The comparison of monolayer cells and alginate embedded cells with or without diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16c2b5d59c2046f06d2d800eb1edbc4
https://doi.org/10.1089/ten.tea.2010.0499
https://doi.org/10.1089/ten.tea.2010.0499
Autor:
Tarjei S. Mikkelsen, Torill Høiby, Davide Cacchiarelli, Jan E. Brinchmann, Sarah R. Herlofsen, Xiaolan Zhang
Publikováno v:
Stem cells (Dayton, Ohio). 32(6)
The transcription factor SOX9 is believed to be the master regulator of chondrogenesis. SOX8 is another SOX group E transcription factor with a high degree of homology to SOX9. Here, we demonstrate that SOX8 mRNA levels decrease during in vitro dedif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f638101db54f9ddc200b37517295eaf7
https://pubmed.ncbi.nlm.nih.gov/24449344
https://pubmed.ncbi.nlm.nih.gov/24449344
Autor:
Jan E. Brinchmann, Axel M. Küchler, Amilton M. Fernandes, Tommy A. Karlsen, Sarah R. Herlofsen, Yngvar Fløisand
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 5, p e62994 (2013)
PLoS ONE, Vol 8, Iss 5, p e62994 (2013)
Lesions of hyaline cartilage do not heal spontaneously, and represent a therapeutic challenge. In vitro engineering of articular cartilage using cells and biomaterials may prove to be the best solution. Patients with osteoarthritis (OA) may require t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaf124c658a6ecee434ec3579714dad
http://europepmc.org/articles/PMC3650033
http://europepmc.org/articles/PMC3650033
Autor:
Jan E. Brinchmann, Tarjei S. Mikkelsen, Hongcang Gu, Leonardo A. Meza-Zepeda, Robbyn Issner, Jan Christian Bryne, Torill Høiby, Patrick Boyle, Michael Coyne, Li Wang, Xiaolan Zhang, Sarah R. Herlofsen, Philippe Collas
Publikováno v:
BMC Genomics
Background For safe clinical application of engineered cartilage made from mesenchymal stem cells (MSCs), molecular mechanisms for chondrogenic differentiation must be known in detail. Changes in gene expression and extracellular matrix synthesis hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d70f0bbe331322fa5811438a9d1cba
https://pubmed.ncbi.nlm.nih.gov/23414147
https://pubmed.ncbi.nlm.nih.gov/23414147