Výsledky vyhledávání - "Sarah R, Anthony"

Akademický článek

HuR expression in adipose tissue mediates energy expenditure and acute thermogenesis independent of UCP1 expression

Autor: Sarah R. Anthony, Adrienne Guarnieri, Lindsey Lanzillotta, Anamarie Gozdiff, Lisa C. Green, Katherine O’Grady, Robert N. Helsley, A. Phillip Owens, Michael Tranter

Publikováno v: Adipocyte, Vol 9, Iss 1, Pp 336-346 (2020)

The goal of this study was to define the functional role of adipocyte-specific expression of the RNA binding protein Human antigen R (HuR). Mice with an adipocyte-specific deletion of HuR (Adipo-HuR−/-) were generated by crossing HuR floxed (HuRfl/

Externí odkaz: https://doaj.org/article/327653bd611d4b6cb45968d881181b15

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HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Autor: Lisa C, Green, Samuel, Slone, Sarah R, Anthony, Adrienne R, Guarnieri, Sharon, Parkins, Shannon M, Shearer, Michelle L, Nieman, Sudeshna, Roy, Jeffrey, Aube, Xiaoqing, Wu, Liang, Xu, Onur, Kanisicak, Michael, Tranter

Publikováno v: Journal of Molecular and Cellular Cardiology. 174:38-46

Cardiac fibrosis is regulated by the activation and phenotypic switching of quiescent cardiac fibroblasts to active myofibroblasts, which have extracellular matrix (ECM) remodeling and contractile functions which play a central role in cardiac remode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f600202cd98249e80b2a05b9e799ee94
https://doi.org/10.1016/j.yjmcc.2022.10.007

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HuR inhibition reduces post-ischemic cardiac remodeling by dampening acute inflammatory gene expression and the innate immune response

Autor: Samuel Slone, Sarah R. Anthony, Lisa C. Green, Michelle L. Nieman, Perwez Alam, Xiaoqing Wu, Sudeshna Roy, Jeffrey Aube, Liang Xu, John N. Lorenz, A. Phillip Owens, Onur Kanisicak, Michael Tranter

Publikováno v: bioRxiv

Myocardial ischemia/reperfusion (I/R) injury and the resulting cardiac remodeling is a common cause of heart failure. The RNA binding protein Human Antigen R (HuR) has been previously shown to reduce cardiac remodeling following both I/R and cardiac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c616617f797378b82d427a86bdf37bc
https://europepmc.org/articles/PMC9882229/

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Adipocyte-specific deletion of HuR induces spontaneous cardiac hypertrophy and fibrosis

Autor: Joshua B. Benoit, Lisa C. Green, Perwez Alam, Salma M Fleifil, Michelle L. Nieman, Onur Kanisicak, A. Phillip Owens, Sam Slone, Anamarie Gozdiff, Michael Tranter, Adrienne R Guarnieri, Sarah R. Anthony

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 321:H228-H241

Adipose tissue homeostasis plays a central role in cardiovascular physiology, and the presence of thermogenically active brown adipose tissue (BAT) has recently been associated with cardiometabolic health. We have previously shown that adipose tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a70e407648093ac0e3c7d39c1a54e591
https://doi.org/10.1152/ajpheart.00957.2020

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HuR expression in adipose tissue mediates energy expenditure and acute thermogenesis independent of UCP1 expression

Autor: Lindsey Lanzillotta, Robert N. Helsley, Michael Tranter, A. Phillip Owens, Lisa C. Green, Katherine O'Grady, Adrienne R Guarnieri, Anamarie Gozdiff, Sarah R. Anthony

Publikováno v: Adipocyte, Vol 9, Iss 1, Pp 336-346 (2020)
Adipocyte
article-version (VoR) Version of Record

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7444ceea45814525d8157d90ad0b4c19
https://doi.org/10.1080/21623945.2020.1782021

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HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Autor: Lisa C Green, Samuel Slone, Sarah R Anthony, Jeffrey Aube, Xiaoqing Wu, Liang Xu, Onur Kanisicak, Michael Tranter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54e9aad06032ad0738a60ecfce8565a1
https://doi.org/10.1101/2022.01.19.476976

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Adipocyte deletion of the RNA binding protein HuR induces cardiac hypertrophy and fibrosis

Autor: Onur Kanisicak, Adrienne R Guarnieri, Sarah R. Anthony, Anamarie Gozdiff, Samuel Slone, Michael Tranter, Michelle L. Nieman, Joshua B. Benoit, Lisa C. Green, Perwez Alam

Adipose tissue continues to gain appreciation for its broad role as an endocrine organ, and disruptions in adipose tissue homeostasis plays a central role in cardiovascular physiology. We have previously shown that expression of the RNA binding prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f0e98c0ee89636d385ce15b493f5dd9
https://doi.org/10.1101/2021.01.19.425776

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Synthesis and PGE2 inhibitory activity of novel diarylheptanoids

Autor: Zachary L. Taylor, Michael Tranter, Léon Le Cozannet-Laidin, Lindsey Lanzillotta, Maxwell S. Boyle, Amber J. Onorato, Richard D. McLane, Sarah R. Anthony

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 28:334-338

Prostaglandin E2 (PGE2) is a lipid mediator of inflammation and its inhibition has become a popular drug target due to its harmful physiological roles. Diarylheptanoids are one class of compounds that have shown successful inhibition of PGE2. This pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32baa4d9b71b5e05fcb67ff93f710e0f
https://doi.org/10.1016/j.bmcl.2017.12.046

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