Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sarah Quillen"'
Autor:
Casey J. Keuthan, Julie A. Schaub, Meihan Wei, Weixiang Fang, Sarah Quillen, Elizabeth Kimball, Thomas V. Johnson, Hongkai Ji, Donald J. Zack, Harry A. Quigley
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13719 (2023)
A major risk factor for glaucomatous optic neuropathy is the level of intraocular pressure (IOP), which can lead to retinal ganglion cell axon injury and cell death. The optic nerve has a rostral unmyelinated portion at the optic nerve head followed
Externí odkaz:
https://doaj.org/article/f8034c9f02e64b5eb5b27706db54c72a
Autor:
Elizabeth C. Kimball, Sarah Quillen, Mary E. Pease, Casey Keuthan, Aru Nagalingam, Donald J. Zack, Thomas V. Johnson, Harry A. Quigley
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Aquaporin 4 is absent from astrocytes in the rodent optic nerve head, despite high expression in the retina and myelinated optic nerve. The purpose of this study was to quantify regional aquaporin channel expression in astrocytes of the porcine and h
Externí odkaz:
https://doaj.org/article/ccc8cec05a494dd98b7445e023863501
Autor:
Elizabeth Kimball, Julie Schaub, Sarah Quillen, Casey Keuthan, Mary Ellen Pease, Arina Korneva, Harry Quigley
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0244123 (2021)
PurposeTo study aquaporin channel expression in astrocytes of the mouse optic nerve (ON) and the response to IOP elevation in mice lacking aquaporin 4 (AQP4 null).MethodsC57BL/6 (B6) and AQP4 null mice were exposed to bead-induced IOP elevation for 3
Externí odkaz:
https://doaj.org/article/47d801fd0fe44be8b2e89ebd41726a67
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238104 (2020)
PurposeTo delineate responses of optic nerve head astrocytes to sustained intraocular pressure (IOP) elevation in mice.MethodsWe elevated IOP for 1 day to 6 weeks by intracameral microbead injection in 4 strains of mice. Astrocyte alterations were st
Externí odkaz:
https://doaj.org/article/2b1b02d983cc40838ead85526bc50102
Autor:
Henry T. Hsueh, Yoo-Chun Kim, Ian Pitha, Matthew D. Shin, Cynthia A. Berlinicke, Renee Ti Chou, Elizabeth Kimball, Julie Schaub, Sarah Quillen, Kirby T. Leo, Hyounkoo Han, Amy Xiao, Youngwook Kim, Matthew Appell, Usha Rai, HyeYoung Kwon, Patricia Kolodziejski, Laolu Ogunnaike, Nicole M. Anders, Avelina Hemingway, Joan L. Jefferys, Abhijit A. Date, Charles Eberhart, Thomas V. Johnson, Harry A. Quigley, Donald J. Zack, Justin Hanes, Laura M. Ensign
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 647 (2021)
Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is one of the major risk factors for glaucoma onset and progression, and available pharmaceutical interventions are exclusively targeted at IOP low
Externí odkaz:
https://doaj.org/article/3232c89326b24142bbf27c0ff670b9ea
Autor:
Casey J Keuthan, Julie Schaub, Meihan Wei, Weixiang Fang, Sarah Quillen, Elizabeth Kimball, Thomas V Johnson, Hongkai Ji, Donald J Zack, Harry A Quigley
Publikováno v:
bioRxiv
A major risk factor for glaucomatous optic neuropathy is the level of intraocular pressure (IOP), which can lead to retinal ganglion cell axon injury and cell death. The optic nerve has a rostral unmyelinated portion at the optic nerve head followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fce47e9d1ca63d5f55efe1af23d390
https://doi.org/10.1101/2023.02.21.529410
https://doi.org/10.1101/2023.02.21.529410
Autor:
Erika A Aguzzi, Kevin Y Zhang, Arumugam Nagalingam, Sarah Quillen, Shreya Hariharakumar, Nitin Chetla, Salaheddine Madhoun, Malia M Edwards, Harry A Quigley, Donald J Zack, Thomas V Johnson
Retinal ganglion cell (RGC) death causes irreversible vision loss in patients with glaucoma and other forms of optic neuropathy because the mammalian retina and optic nerve lack endogenous regenerative capacity. RGC transplantation and optic nerve re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83b6a31c560f110eb9efd69d32eb08c5
https://doi.org/10.1101/2022.12.13.519327
https://doi.org/10.1101/2022.12.13.519327
Autor:
Salaheddine, Madhoun, Manuela Tosi Comelis, Martins, Arina, Korneva, Thomas V, Johnson, Elizabeth, Kimball, Sarah, Quillen, Mary Ellen, Pease, Malia, Edwards, Harry, Quigley
Publikováno v:
Exp Eye Res
To identify changes in response to experimental intraocular pressure (IOP) elevation associated with the laminin α1 nmf223 mutation in mice. Laminin mutant (LM) mice (Lama1(nmf223)) and C57BL/6J (B6) mice in two age groups each (4-5 months and >1 ye
Autor:
Laurence Wechsler, Harry A. Quigley, Kevin Y. Zhang, Donald J. Zack, Sarah Quillen, Caitlyn Tuffy, Joseph L. Mertz, Thomas V. Johnson
Publikováno v:
Stem Cell Reports
Summary Retinal ganglion cell (RGC) replacement holds potential for restoring vision lost to optic neuropathy. Transplanted RGCs must undergo neuroretinal integration to receive afferent visual signals for processing and efferent transmission. To dat
Autor:
Salaheddine Madhoun, Manuela Tosi Comelis Martins, Arina Korneva, Thomas V. Johnson, Elizabeth Kimball, Sarah Quillen, Mary Ellen Pease, Malia Edwards, Harry Quigley
Publikováno v:
Experimental Eye Research. 226:109341