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pro vyhledávání: '"Sarah Provazza"'
Autor:
Niina Sokolova, Shi Pan, Sarah Provazza, Gisela Beutner, Marko Vendelin, Rikke Birkedal, Shey-Shing Sheu
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83214 (2013)
ADP is not only a key substrate for ATP generation, but also a potent inhibitor of mitochondrial permeability transition pore (mPTP). In this study, we assessed how oxidative stress affects the potency of ADP as an mPTP inhibitor and whether its redu
Externí odkaz:
https://doaj.org/article/ef49187f383348cc9b781f3540c19252
Autor:
Alina Ainbinder, Niina Sokolova, Marko Vendelin, Gisela Beutner, Sarah Provazza, Dieter Brdiczka, Shey-Shing Sheu, Rikke Birkedal
Publikováno v:
Biophysical Journal. 100:458a-459a
Mitochondrial ADP serves at least two important functions: provides a substrate for ATP generation and inhibits the mitochondrial permeability transition pore (mPTP). The mechanism for the inhibitory effect of ADP on mPTP remains unclear. Moreover, t