Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Sarah Pringle"'
Autor:
Paola Serrano Martinez, Martti Maimets, Reinier Bron, Ronald van Os, Gerald de Haan, Sarah Pringle, Robert P. Coppes
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105047- (2022)
Summary: Stem/progenitor cells are required for maintenance of salivary gland (SG) function and serve as untapped reservoirs to create functional cells. Despite recent advancements in the identification of stem/progenitor pools, in the submandibular
Externí odkaz:
https://doaj.org/article/fd23531faa8940f68d9483e35bd2f105
Autor:
Gwenny M. Verstappen, Lu Gao, Sarah Pringle, Erlin A. Haacke, Bert van der Vegt, Silvia C. Liefers, Vishal Patel, Yanhua Hu, Sumanta Mukherjee, Julie Carman, Laurence C. Menard, Frederik K. L. Spijkervet, Arjan Vissink, Hendrika Bootsma, Frans G. M. Kroese
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundWhile all salivary glands (SGs) can be involved in primary Sjögren’s syndrome (pSS), their respective role in pathogenesis remains unclear. Our objective was to assess immunopathway activation in paired parotid and labial gland tissue fr
Externí odkaz:
https://doaj.org/article/f633d64c90d94a9891b4cb74558cbd90
Autor:
Sarah Pringle, Bert van der Vegt, Xiaoyan Wang, Nico van Bakelen, T. Jeroen N. Hiltermann, Fred K. L. Spijkervet, Arjan Vissink, Frans G. M. Kroese, Hendrika Bootsma
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Salivary glands (SGs) can be damaged by immune checkpoint inhibitor (ICI) therapy. In patients with ICI-induced SG dysfunction, 60% progress to fulfill classification criteria for primary Sjögren's syndrome (pSS), owing to immune foci in
Externí odkaz:
https://doaj.org/article/18fc0c184d6044a989b0ea1af47b9109
Autor:
Martti Maimets, Cecilia Rocchi, Reinier Bron, Sarah Pringle, Jeroen Kuipers, Ben N.G. Giepmans, Robert G.J. Vries, Hans Clevers, Gerald de Haan, Ronald van Os, Robert P. Coppes
Publikováno v:
Stem Cell Reports, Vol 6, Iss 1, Pp 150-162 (2016)
Adult stem cells are the ultimate source for replenishment of salivary gland (SG) tissue. Self-renewal ability of stem cells is dependent on extrinsic niche signals that have not been unraveled for the SG. The ductal compartment in SG has been identi
Externí odkaz:
https://doaj.org/article/5a099b58bf6c4ebda179952b959803d3
Autor:
Xiaoyan Wang, Abeer Shaalan, Silvia Liefers, Julie Coudenys, Dirk Elewaut, Gordon B Proctor, Hendrika Bootsma, Frans G M Kroese, Sarah Pringle
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0200212 (2018)
The autoimmune disease primary Sjögren's syndrome (pSS) is characterized by hypofunction of the salivary glands (SGs), the cause of which is not correlated to lymphocytic SG infiltration, as prevailing dogma often states. We knocked out the NF-κB p
Externí odkaz:
https://doaj.org/article/8e3ef71915434afea7ee0d79750211ac
Autor:
Ting Yang, Konstatina Delli, Adriaan D. Coumou, Bert van der Vegt, Frans G.M. Kroese, Hendrika Bootsma, Sarah Pringle
Publikováno v:
Clinical and Experimental Rheumatology. 40(12):2428-2433
According to a recent survey of patients with the autoimmune disease primary Sjögren's syndrome (pSS), dry eye symptoms are present in 95-98% of pSS patients. As one of the most disabling symptoms mentioned by pSS patients, dry eyes have demonstrabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ba54e55720de2e7ac4d07e547659a4
https://doi.org/10.55563/clinexprheumatol/z1lzb1
https://doi.org/10.55563/clinexprheumatol/z1lzb1
Publikováno v:
Journal of Dental Research. 101(11):1274-1288
Oral and craniofacial tissues are uniquely adapted for continuous and intricate functioning, including breathing, feeding, and communication. To achieve these vital processes, this complex is supported by incredible tissue diversity, variously compos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c8690494bda59eac1dff8ca9afde1a
https://hdl.handle.net/11370/6033a56f-1685-4e23-93a7-88ccd1f1b3b4
https://hdl.handle.net/11370/6033a56f-1685-4e23-93a7-88ccd1f1b3b4
Autor:
Annemieke M. H. Boots, William F Jiemy, Kornelis S M van der Geest, Wayel H. Abdulahad, Elisabeth Brouwer, Peter Heeringa, Maria Sandovici, Yannick van Sleen, Sarah Pringle
Publikováno v:
Arthritis & Rheumatology, 73(12), 2327-2337. Wiley
Objective Macrophages mediate inflammation, angiogenesis, and tissue destruction in giant cell arteritis (GCA). Serum levels of the macrophage-associated protein YKL-40 (chitinase 3-like protein 1), previously linked to angiogenesis and tissue remode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d738fd1e0f3e88d9af26cf15975bc16
https://research.rug.nl/en/publications/f6013178-7309-4a7c-bc31-661157209057
https://research.rug.nl/en/publications/f6013178-7309-4a7c-bc31-661157209057
Autor:
Sarah Pringle, Gwenny M. Verstappen, Marthe S. van Ginkel, Uzma Nakshbandi, Zayferick Girigoria, Hendrika Bootsma, Bert van der Vegt, Frans G.M. Kroese
Publikováno v:
Clinical and experimental rheumatology. 40(12)
In patients with primary Sjögren’s syndrome (pSS), inflamed salivary gland (SG) tissue may contain lymphoepithelial lesions (LELs). LELs are histopathological phenomena whereby B cells are present in hyperplastic ductal epithelium of the SG. Despi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeaca8b30d19f21f8932b148d3515de4
https://pubmed.ncbi.nlm.nih.gov/36226606
https://pubmed.ncbi.nlm.nih.gov/36226606
Publikováno v:
Nature Reviews. Rheumatology
In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland epithelium in pSS, including the nuclear factor-κB pathway, the infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2b2176d8b2ac4879a48d06f4953efc
http://europepmc.org/articles/PMC8081003
http://europepmc.org/articles/PMC8081003