Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sarah Powell-BRett"'
Autor:
Oladimeji Abudu, Duy Nguyen, Isabel Millward, Julia E. Manning, Mussarat Wahid, Abbey Lightfoot, Francesca Marcon, Reena Merard, Sandra Margielewska-Davies, Keith Roberts, Rachel Brown, Sarah Powell-Brett, Samantha M. Nicol, Fouzia Zayou, Wayne D. Croft, Hayden Pearce, Paul Moss, Asif J. Iqbal, Helen M. McGettrick
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116283- (2024)
Background: Galectins (Gal’s) are a family of carbohydrate-binding proteins that are known to support the tumour microenvironment through their immunosuppressive activity and ability to promote metastasis. As such they are attractive therapeutic ta
Externí odkaz:
https://doaj.org/article/c165695e9a5647bc8ea433d32b708818
Autor:
Wayne Croft, Hayden Pearce, Sandra Margielewska-Davies, Lindsay Lim, Samantha M Nicol, Fouzia Zayou, Daniel Blakeway, Francesca Marcon, Sarah Powell-Brett, Brinder Mahon, Reena Merard, Jianmin Zuo, Gary Middleton, Keith Roberts, Rachel M Brown, Paul Moss
Publikováno v:
eLife, Vol 12 (2023)
Pancreatic ductal adenocarcinoma has a poor clinical outcome and responses to immunotherapy are suboptimal. Stromal fibroblasts are a dominant but heterogenous population within the tumor microenvironment and therapeutic targeting of stromal subsets
Externí odkaz:
https://doaj.org/article/d7357419260341daa6df22adc8ce75ad
Autor:
Lewis A. Hall, Sarah Powell-Brett, Oscar Thompson, Daniel Smith, Elizabeth Bradley, Stacey Smith, Suzanne Vickrage, Joanne Kemp-Blake, Keith J. Roberts, Tahir Shah
Publikováno v:
Cancers, Vol 15, Iss 7, p 1933 (2023)
Somatostatin-analogues (SSAs) are a first-line treatment of unresectable neuroendocrine tumours (NETs). However, SSAs inhibit pancreatic secretions, which could lead to pancreatic exocrine insufficiency (PEI). PEI is known to be detrimental to patien
Externí odkaz:
https://doaj.org/article/f4e58c28e83c4b479cc9a822436eb0d5
Publikováno v:
Cancers, Vol 13, Iss 7, p 1669 (2021)
Improving outcomes among patients with resectable pancreatic cancer is one of the greatest challenges of modern medicine. Major improvements in survival will result from the development of novel therapies. However, optimising existing pathways, so th
Externí odkaz:
https://doaj.org/article/2bf868f8658b4c3fa832a3545d64aa82
Publikováno v:
Pancreatology. 23:283-293
Autor:
Syed S. Raza, Anisa Nutu, Sarah Powell-Brett, Alessio Marchetti, Giampaolo Perri, Amanda Carvalheiro Boteon, James Hodson, Nikolaos Chatzizacharias, Bobby V. Dasari, John Isaac, Manual Abradelo, Ravi Marudanayagam, Darius F. Mirza, J. Keith Roberts, Giovanni Marchegiani, Roberto Salvia, Robert P. Sutcliffe
Publikováno v:
Surgery. 173:492-500
Autor:
Hayden Pearce, Wayne Croft, Samantha M. Nicol, Sandra Margielewska-Davies, Richard Powell, Richard Cornall, Simon J. Davis, Francesca Marcon, Matthew R. Pugh, Éanna Fennell, Sarah Powell-Brett, Brinder S. Mahon, Rachel M. Brown, Gary Middleton, Keith Roberts, Paul Moss
Publikováno v:
Cancer Immunology Research. 11:435-449
Pancreatic ductal adenocarcinoma (PDAC) has a poor clinical outlook. Responses to immune checkpoint blockade are suboptimal and a much more detailed understanding of the tumor immune microenvironment is needed if this situation is to be improved. Her
Autor:
Oscar Thompson, Lewis Hall, Keith Roberts, Elizabeth Bradley, Sarah Powell-Brett, Rupaly Pande, Tahir Shah
Publikováno v:
HPB. 24:1921-1929
Treatment with somatostatin analogues (SSAs) or pancreaticoduodenectomy frequently causes malnutrition-inducing pancreatic exocrine insufficiency. This single-centre retrospective cohort study aimed to establish whether pancreatic enzyme replacement
Autor:
Syed S. Raza, Oana A. Nutu, Sarah Powell-Brett, Amanda Carvalheiro Boteon, James Hodson, Manuel Abradelo, Bobby Dasari, John Isaac, Nikolaos Chatzizacharias, Ravi Marudanayagam, Darius F. Mirza, J. Keith Roberts, Robert P. Sutcliffe
Publikováno v:
HPB. 24:1720-1728
To determine whether the short-term benefits associated with an enhanced recovery after surgery programme (ERAS) following pancreaticoduodenectomy (PD) vary with age.830 consecutive patients who underwent PD between January 2009 and March 2019 were d
Autor:
Paul Moss, Keith Roberts, Gary Middleton, Rachel M. Brown, Brinder S. Mahon, Sarah Powell-Brett, Éanna Fennell, Matthew R. Pugh, Francesca Marcon, Simon J. Davis, Richard Cornall, Richard Powell, Sandra Margielewska-Davies, Samantha M. Nicol, Wayne Croft, Hayden Pearce
Supplementary Figures S1 - S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e42f4ba5f8a45010341e7e26126c08b
https://doi.org/10.1158/2326-6066.22551825.v1
https://doi.org/10.1158/2326-6066.22551825.v1