Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Sarah Pirrie"'
Autor:
Nicholas James, Sarah Pirrie, Wenyu Liu, James Catto, Kieran Jefferson, Prashant Patel, Ana Hughes, Ann Pope, Veronica Nanton, Harriet P Mintz, Allen Knight, Jean Gallagher, Richard T Bryan
Publikováno v:
Health Technology Assessment, Vol 28, Iss 42 (2024)
Background Transurethral resection of bladder tumour has been the mainstay of bladder cancer staging for > 60 years. Staging inaccuracies are commonplace, leading to delayed treatment of muscle-invasive bladder cancer. Multiparametric magnetic resona
Externí odkaz:
https://doaj.org/article/3313e5da137e49fb902c90a9ef027687
Autor:
Sally Wheelwright, Lucy Matthews, Valerie Jenkins, Shirley May, Daniel Rea, Pat Fairbrother, Claire Gaunt, Jennie Young, Sarah Pirrie, Matthew G. Wallis, Lesley Fallowfield, on behalf of the LORIS Trial Management Group
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background The LOw RISk DCIS (LORIS) study was set up to compare conventional surgical treatment with active monitoring in women with ductal carcinoma in situ (DCIS). Recruitment to trials with a surveillance arm is known to be challenging,
Externí odkaz:
https://doaj.org/article/503fbba1f83546d5b5e97ab96d86990c
Autor:
Dennis C. Sgroi, Kai Treuner, Yi Zhang, Tammy Piper, Ranelle Salunga, Ikhlaaq Ahmed, Lucy Doos, Sarah Thornber, Karen J. Taylor, Elena Brachtel, Sarah Pirrie, Catherine A. Schnabel, Daniel Rea, John M. S. Bartlett
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Background Multiple clinical trials demonstrate consistent but modest benefit of adjuvant extended endocrine therapy (EET) in HR + breast cancer patients. Predictive biomarkers to identify patients that benefit from EET are critical to balan
Externí odkaz:
https://doaj.org/article/f73219a1ffd7495699a8f9ef0b2330f6
Autor:
Nicholas D. James, Ayesha Ali, Ann Pope, Amisha Desai, Daniel Ford, Robert Stevenson, Anjali Zarkar, Sarah Pirrie, the CANTATA investigators
Publikováno v:
BJUI Compass, Vol 3, Iss 6, Pp 484-493 (2022)
Abstract Objectives To assess cabazitaxel versus docetaxel re‐challenge for the treatment of metastatic castrate refractory prostate cancer (CRPC) patients previously treated with docetaxel at inception of primary hormone therapy. Patients and Meth
Externí odkaz:
https://doaj.org/article/273a083bdc144112b88a403136099e0a
Autor:
Nicholas James, Sarah Pirrie, Ann Pope, Darren Barton, Lazaros Andronis, Ilias Goranitis, Stuart Collins, Duncan McLaren, Joe O’Sullivan, Chris Parker, Emilio Porfiri, John Staffurth, Andrew Stanley, James Wylie, Sharon Beesley, Alison Birtle, Janet Brown, Prabir Chakraborti, Martin Russell, Lucinda Billingham
Publikováno v:
Health Technology Assessment, Vol 20, Iss 53 (2016)
Background: Bony metastatic castration-refractory prostate cancer is associated with a poor prognosis and high morbidity. TRAPEZE was a two-by-two factorial randomised controlled trial of zoledronic acid (ZA) and strontium-89 (Sr-89), each combined w
Externí odkaz:
https://doaj.org/article/c615d29188e14af3b091335974572196
Autor:
Stuart A. McIntosh, Charlotte E. Coles, David Dodwell, Kenneth Elder, Jessica Foster, Claire Gaunt, Amanda Kirkham, Iain Lyburn, Jenna Morgan, Sangeetha Paramasivan, Sarah E. Pinder, Sarah Pirrie, Shelley Potter, Tracy Roberts, Nisha Sharma, Hilary Stobart, Elizabeth Southgate, Sian Taylor-Phillips, Matthew Wallis, Daniel Rea
Publikováno v:
Cancer Research. 83:OT3-20
Background: Mammographic screening programmes reduce breast cancer mortality, but detect many small tumours with favourable biological features which may not progress during a woman’s lifetime. Screen-detected cancers are treated with standard surg
Autor:
Nicholas D, James, Wenyu, Liu, Sarah, Pirrie, Baljit, Kaur, Carey, Hendron, Daniel, Ford, Anjali, Zarkar, Richard, Viney, Elizabeth, Southgate, Amisha, Desai, Syed A, Hussain
Publikováno v:
BJU International. 131:63-72
To assess feasibility and preliminary efficacy of adding cetuximab to standard chemoradiotherapy for muscle-invasive bladder cancer.TUXEDO was a prospective, single-arm, open-label, phase I/II trial conducted in six UK hospitals. Cetuximab was admini
Autor:
Stuart A McIntosh, Charlotte E Coles, Carmel Conefrey, David Dodwell, Kenneth Elder, Jessica Foster, Claire Gaunt, Amanda Kirkham, Iain Lyburn, Jenna Morgan, Sangeetha Paramasivan, Sarah Pinder, Sarah Pirrie, Shelley Potter, Tracy Roberts, Nisha Sharma, Hilary Stobart, Elizabeth Southgate, Sian Taylor-Phillips, Matthew Wallis, Daniel Rea
Publikováno v:
Cancer Research. 82:OT1-06
Background:. Mammographic screening programmes have been shown to reduce breast cancer mortality. However, they detect many small tumours with favourable biological features which may not progress during a woman’s lifetime. These are treated with s
Autor:
Stuart A. McIntosh, Charlotte E. Coles, David Dodwell, Kenneth Elder, Jessica Foster, Claire Gaunt, Amanda Kirkham, Iain Lyburn, Jenna Morgan, Sarah E. Pinder, Sarah Pirrie, Shelley Potter, Tracy Roberts, Nisha Sharma, Hilary Stobart, Elizabeth Southgate, Sian Taylor-Phillips, Matthew Wallis, Daniel Rea, Sangeetha Paramasivan
Publikováno v:
Cancer Research. 83:P6-05
Background SMALL (ISRCTN 12240119) is a novel UK phase III multicentre randomised trial comparing vacuum-assisted excision (VAE) to surgery for small screen-detected breast cancers with biologically favourable characteristics. Acceptance by the clini
Autor:
Elena F. Brachtel, Tammy Piper, Catherine A. Schnabel, Daniel Rea, Lucy Doos, Yi Zhang, Dennis C. Sgroi, John M. S. Bartlett, Sarah Thornber, Ikhlaaq Ahmed, Ranelle C. Salunga, Kai Treuner, Sarah Pirrie, Karen J Taylor
Publikováno v:
Cancer Research. 81:GS4-09
Background: Several biomarkers such as estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR) and Ki67 have been implicated in the pathogenesis and/or as prognostic biomarkers of breast cancer, and are utilized to determine treatm