Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sarah Pegno"'
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure S4. DHODH is a target of sensitivity in PTEN deficient cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90fa589eb11f309ff4e13f99524462e
https://doi.org/10.1158/2159-8290.22532081
https://doi.org/10.1158/2159-8290.22532081
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure S2. Pyrimidine synthesis is upregulated in Pten-/- MEFs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507cf2594f7f5a466c1bf6edc78c24a0
https://doi.org/10.1158/2159-8290.22532087
https://doi.org/10.1158/2159-8290.22532087
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure S1. Loss of Pten increases proliferation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c8a2420ef4585e1dc147d8eca87529
https://doi.org/10.1158/2159-8290.22532090.v1
https://doi.org/10.1158/2159-8290.22532090.v1
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure S5. Leflunomide inhibits PTEN mutant tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fd2a532ddb588bb0aaf2db21e3f482
https://doi.org/10.1158/2159-8290.22532078.v1
https://doi.org/10.1158/2159-8290.22532078.v1
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure S3. PTEN loss confers sensitivity to de novo pyrimidine synthesis inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b753423c1abc097ce69828fbf7a570
https://doi.org/10.1158/2159-8290.22532084
https://doi.org/10.1158/2159-8290.22532084
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure S6. ATR signaling defects contribute to synthetic lethality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10007f268e939fd55db301cd76d94539
https://doi.org/10.1158/2159-8290.22532075
https://doi.org/10.1158/2159-8290.22532075
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure S7. Model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3d411ea35622d963369f94755b8ec6
https://doi.org/10.1158/2159-8290.22532069.v1
https://doi.org/10.1158/2159-8290.22532069.v1
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure Legends, Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e5b479547aa9aedce46d8d91bed27f9
https://doi.org/10.1158/2159-8290.22532096.v1
https://doi.org/10.1158/2159-8290.22532096.v1
Autor:
Ramon Parsons, Lewis C. Cantley, John M. Asara, Vundavalli V. Murty, Raymund Yong, Sarah Schoenfeld, Sarah Pegno, Nicole Steinbach, Sait Ozturk, Elias Stratikopoulos, Deepti Mathur
Supplementary Figure Legends, Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::109a2b8c1a13c3d86bccb4fe86b104ff
https://doi.org/10.1158/2159-8290.22532096
https://doi.org/10.1158/2159-8290.22532096
Autor:
Poulikos I. Poulikakos, Ramon Parsons, Nicole Kiess, Pamela Cheung, Sarah Pegno, Hank Schmidt, Xuewei Wu, Elias E. Stratikopoulos, Matthias Szabolcs, Cheung Kakit
Publikováno v:
Oncogene. 38:47-59
Estrogen dependence is major driver of ER + breast cancer, which is associated with PI3K mutation. PI3K inhibition (PI3Ki) can restore dependence on ER signaling for some hormone therapy-resistant ER + breast cancers, but is ineffective in others. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da54fed3dd1a2660624bd202cb079473
https://doi.org/10.1038/s41388-018-0436-4
https://doi.org/10.1038/s41388-018-0436-4
