Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sarah Pedretti"'
Autor:
Andrew Gibson, Ramesh Ram, Rama Gangula, Yueran Li, Eric Mukherjee, Amy M. Palubinsky, Chelsea N. Campbell, Michael Thorne, Katherine C. Konvinse, Phuti Choshi, Pooja Deshpande, Sarah Pedretti, Mark W. Fear, Fiona M. Wood, Richard T. O’Neil, Celestine N. Wanjalla, Spyros A. Kalams, Silvana Gaudieri, Rannakoe J. Lehloenya, Samuel S. Bailin, Abha Chopra, Jason A. Trubiano, On behalf of the AUS-SCAR Consortium, Jonny G. Peter, On behalf of the AFRiSCAR Consortium, Simon A. Mallal, Elizabeth J. Phillips
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen (HLA) class I-restricted CD8+ T cells. For unbiased assessment of cellular immunopat
Externí odkaz:
https://doaj.org/article/b950cd1193724ab680aaea5c6885ab68
Autor:
Tafadzwa Chimbetete, Phuti Choshi, Sarah Pedretti, Mireille Porter, Riyaadh Roberts, Rannakoe Lehloenya, Jonathan Peter
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionDrug Reaction with Eosinophilia Systemic Symptoms (DRESS) is more common in persons living with HIV (PLHIV), and first-line anti-TB drugs (FLTDs) and cotrimoxazole are the commonest offending drugs. Limited data is available on the skin i
Externí odkaz:
https://doaj.org/article/0c14f65ba1ec4f0cb5351ae850d4c781
Corrigendum: Dose Dependent Antimicrobial Cellular Cytotoxicity—Implications for ex vivo Diagnostics
Autor:
Ana Copaescu, Phuti Choshi, Sarah Pedretti, Effie Mouhtouris, Jonathan Peter, Jason A. Trubiano
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b016b7c78e0e42f8af73b6e0ca2685ac
Autor:
Ana Copaescu, Phuti Choshi, Sarah Pedretti, Effie Mouhtouris, Jonathan Peter, Jason A. Trubiano
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Introduction:Ex vivo and in vitro diagnostics, such as interferon-γ (IFN-γ) release enzyme linked ImmunoSpot (ELISpot) and flow cytometry, are increasingly employed in the research and diagnostic setting for severe T-cell mediated hypersensitivity.
Externí odkaz:
https://doaj.org/article/fe032549f2ee4eba9074af484a1cfadb
Autor:
Sarah Pedretti, Marie-Claude Brulhart-Meynet, Fabrizio Montecucco, Sandrine Lecour, Richard W James, Miguel A Frias
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218432 (2019)
PurposeHigh density lipoprotein (HDL) protects against myocardial infarction via mechanisms that remain unclear. STAT3 (signal transducer and activator of transcription 3) plays a key role in HDL-induced cardioprotection. In the heart, microRNAs (miR
Externí odkaz:
https://doaj.org/article/c399d7b48f8948e0a140efecba8b1a1e
Autor:
Nicholas J. Woudberg, Sarah Pedretti, Sandrine Lecour, Rainer Schulz, Nicolas Vuilleumier, Richard W. James, Miguel A. Frias
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2018)
The cholesterol concentrations of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) have traditionally served as risk factors for cardiovascular disease. As such, novel therapeutic interventions aiming to raise HDL cholesterol have bee
Externí odkaz:
https://doaj.org/article/4036e3773a8e4d43b39ef36393da9c67
Autor:
Marie-Claude Brulhart-Meynet, Vincent Braunersreuther, Jonas Brinck, Fabrizio Montecucco, Jean-Christophe Prost, Aurelien Thomas, Katia Galan, Graziano Pelli, Sarah Pedretti, Nicolas Vuilleumier, François Mach, Sandrine Lecour, Richard W James, Miguel A Frias
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119664 (2015)
BackgroundNew evidence shows that high density lipoproteins (HDL) have protective effects beyond their role in reverse cholesterol transport. Reconstituted HDL (rHDL) offer an attractive means of clinically exploiting these novel effects including ca
Externí odkaz:
https://doaj.org/article/ff3c8d5ee6904f57aade61fef757dd33
Autor:
Tafadzwa Chimbetete, Chloe Buck, Phuti Choshi, Rose Selim, Sarah Pedretti, Sherrie Jill Divito, Elizabeth Jane Phillips, Rannakoe Lehloenya, Jonny Peter
Publikováno v:
J Invest Dermatol
Skin diseases are hallmarks of progressive HIV-related immunosuppression, with severe noninfectious inflammatory and hypersensitivity conditions as common as opportunistic infections. Conditions such as papular pruritic eruption are AIDS defining, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c823fd81b19c26cdea738be17984aff
https://doi.org/10.1016/j.jid.2022.07.035
https://doi.org/10.1016/j.jid.2022.07.035
Autor:
Mireille Porter, Phuti Choshi, Sarah Pedretti, Tafadzwa Chimbetete, Rhodine Smith, Graeme Meintjes, Elizabeth Phillips, Rannakoe Lehloenya, Jonny Peter
Publikováno v:
J Invest Dermatol
Severe cutaneous adverse reactions related to first-line antituberculosis drugs are associated with high mortality and long-term morbidity. Oral sequential drug challenge, as a form of drug provocation testing, helps to salvage therapy by identifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0422dec74391c65959e1faf9191d956
https://pubmed.ncbi.nlm.nih.gov/35659939
https://pubmed.ncbi.nlm.nih.gov/35659939
Autor:
Fabrizio Montecucco, Marie-Claude Brulhart-Meynet, Miguel Frias, Sandrine Lecour, Richard W. James, Sarah Pedretti
Publikováno v:
PLoS ONE
PLOS ONE, Vol. 14, No 6 (2019) P. e0218432
PLoS ONE, Vol 14, Iss 6, p e0218432 (2019)
PLOS ONE, Vol. 14, No 6 (2019) P. e0218432
PLoS ONE, Vol 14, Iss 6, p e0218432 (2019)
PurposeHigh density lipoprotein (HDL) protects against myocardial infarction via mechanisms that remain unclear. STAT3 (signal transducer and activator of transcription 3) plays a key role in HDL-induced cardioprotection. In the heart, microRNAs (miR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784420c6725f64482ce71000e28dcd54
http://europepmc.org/articles/PMC6586303
http://europepmc.org/articles/PMC6586303