Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Sarah P. Thayer"'
Autor:
Neha Zutshi, Bhopal C. Mohapatra, Pinaki Mondal, Wei An, Benjamin T. Goetz, Shuo Wang, Sicong Li, Matthew D. Storck, David F. Mercer, Adrian R. Black, Sarah P. Thayer, Jennifer D. Black, Chi Lin, Vimla Band, Hamid Band
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109912- (2024)
Summary: Receptor tyrosine kinases (RTKs) control stem cell maintenance vs. differentiation decisions. Casitas B-lineage lymphoma (CBL) family ubiquitin ligases are negative regulators of RTKs, but their stem cell regulatory roles remain unclear. Her
Externí odkaz:
https://doaj.org/article/768c3a8058a948e9abfe75334d310948
Autor:
Neha Zutshi, Bhopal C. Mohapatra, Pinaki Mondal, Wei An, Benjamin T. Goetz, Shuo Wang, Sicong Li, Matthew D. Storck, David F. Mercer, Adrian R. Black, Sarah P. Thayer, Jennifer D. Black, Chi Lin, Vimla Band, Hamid Band
Publikováno v:
bioRxiv
SUMMARYAmong the signaling pathways that control the stem cell self-renewal and maintenance vs. acquisition of differentiated cell fates, those mediated by receptor tyrosine kinase (RTK) activation are well established as key players. CBL family ubiq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01a912287f759bc2ea932ce30cf047f
https://europepmc.org/articles/PMC10245689/
https://europepmc.org/articles/PMC10245689/
Autor:
Ronald A. DePinho, Sarah P. Thayer, Lynda Chin, Y. Alan Wang, Shannon J. Turley, Nabeel Bardeesy, Aram F. Hezel, Yonghong Xiao, Simona Colla, Alexei Protopopov, Brian Malinn, Shan Jiang, Samuel R. Perry, Carol Lim, Ji-hye Paik, Alec C. Kimmelman, Hongwu Zheng, Xiaojia Ren, Wei Wang, Yingchun Liu, Hailei Zhang, Eliot Fletcher-Sananikone, Haiyan Yan, Gerald C. Chu, Stephanie M. Zimmerman, Anant Vinjamoori, Kutlu G. Elpek, Haoqiang Ying
Supplementary Tables 1-2, Figures 1-8 from PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094d3948b41f178ad853d38243301357
https://doi.org/10.1158/2159-8290.22529363.v1
https://doi.org/10.1158/2159-8290.22529363.v1
Autor:
Kimberly A. Kelly, Sarah P. Thayer, Andrew L. Warshaw, Mark Williams, Todd W. Bauer, Castillo Carlos Fernández-del, Mari Mino-Kenudson, Stephanie Thomas, Dirk Bausch
CCR Translation for This Article from Plectin-1 as a Novel Biomarker for Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7dfcf8e62919828ea1647027b29f7d
https://doi.org/10.1158/1078-0432.22444464
https://doi.org/10.1158/1078-0432.22444464
Autor:
Kimberly A. Kelly, Sarah P. Thayer, Andrew L. Warshaw, Mark Williams, Todd W. Bauer, Castillo Carlos Fernández-del, Mari Mino-Kenudson, Stephanie Thomas, Dirk Bausch
Purpose: We are in great need of specific biomarkers to detect pancreatic ductal adenocarcinoma (PDAC) at an early stage, ideally before invasion. Plectin-1 (Plec1) was recently identified as one such biomarker. However, its suitability as a specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d5a49cbf24c11f3afd260085fbacde
https://doi.org/10.1158/1078-0432.c.6520182
https://doi.org/10.1158/1078-0432.c.6520182
Autor:
Andrew P. McMahon, David Rowitch, Roderick T. Bronson, Sarah P. Thayer, Elena Y. Rakhlin, Keith L. Ligon, Junhao Mao
We report a novel mouse model for the generation of sporadic tumors and show the efficiency of this approach by surveying Hedgehog (Hh)–related tumors. Up-regulation of the Hh pathway is achieved by conditionally regulated expression of an activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329575beab790c689c6e9bd4672e17de
https://doi.org/10.1158/0008-5472.c.6494432
https://doi.org/10.1158/0008-5472.c.6494432
Autor:
Andrew P. McMahon, David Rowitch, Roderick T. Bronson, Sarah P. Thayer, Elena Y. Rakhlin, Keith L. Ligon, Junhao Mao
Supplementary Figures 1-4 from A Novel Somatic Mouse Model to Survey Tumorigenic Potential Applied to the Hedgehog Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fff02bbab795bbf0eb5cfa19ae25dc
https://doi.org/10.1158/0008-5472.22364924
https://doi.org/10.1158/0008-5472.22364924
Autor:
Andrew P. McMahon, David Rowitch, Roderick T. Bronson, Sarah P. Thayer, Elena Y. Rakhlin, Keith L. Ligon, Junhao Mao
Supplementary Tables 1-3 from A Novel Somatic Mouse Model to Survey Tumorigenic Potential Applied to the Hedgehog Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cb5e658b1e7136bd35c01b03f92281
https://doi.org/10.1158/0008-5472.22364918
https://doi.org/10.1158/0008-5472.22364918
Autor:
Junpei Yamaguchi, Andrew S. Liss, Alexandra Sontheimer, Mari Mino-Kenudson, Carlos Fernández-del Castillo, Andrew L. Warshaw, Sarah P. Thayer
Publikováno v:
Stem Cell Research, Vol 15, Iss 1, Pp 190-202 (2015)
Pancreatic duct glands (PDGs) have molecular features known to mark stem cell niches, but their function remains to be determined. To investigate the role of PDGs as a progenitor niche, PDGs were analyzed in both humans and mice. Cells were character
Externí odkaz:
https://doaj.org/article/ccd2aa3f97f54192a882e309ffe78903
Autor:
Ilaria Pergolini, Vicente Morales-Oyarvide, Mari Mino-Kenudson, Kim C Honselmann, Matthew W Rosenbaum, Sabikun Nahar, Marina Kem, Cristina R Ferrone, Keith D Lillemoe, Nabeel Bardeesy, David P Ryan, Sarah P Thayer, Andrew L Warshaw, Carlos Fernández-Del Castillo, Andrew S Liss
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182855 (2017)
Patient-derived xenograft (PDX) tumors are powerful tools to study cancer biology. However, the ability of PDX tumors to model the biological and histological diversity of pancreatic ductal adenocarcinoma (PDAC) is not well known. In this study, we s
Externí odkaz:
https://doaj.org/article/bf4d5669542f4d358dfa11126546b659