Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sarah P Sherlock"'
Autor:
Hisanori Kosuge, Sarah P Sherlock, Toshiro Kitagawa, Masahiro Terashima, Joëlle K Barral, Dwight G Nishimura, Hongjie Dai, Michael V McConnell
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14523 (2011)
FeCo/graphitic-carbon nanocrystals (FeCo/GC) are biocompatible, high-relaxivity, multi-functional nanoparticles. Macrophages represent important cellular imaging targets for assessing vascular inflammation. We evaluated FeCo/GC for vascular macrophag
Externí odkaz:
https://doaj.org/article/96b5e5eeede14413a8d27fce38ba4bf9
Autor:
Mikkel Østergaard, Joseph Wu, Lara Fallon, Sarah P. Sherlock, Cunshan Wang, Dona Fleishaker, Keith S. Kanik, Walter P. Maksymowych
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 4, Pp 1001-1020 (2023)
Abstract Introduction This post hoc analysis of phase 2 trial data assessed the efficacy of tofacitinib on magnetic resonance imaging (MRI) outcomes with the detailed anatomy-based Canada–Denmark (CANDEN) MRI scoring system and evaluated tofacitini
Externí odkaz:
https://doaj.org/article/900707b07b8f48438d518165018deb9b
Autor:
Sarah P. Sherlock, Jeffrey Palmer, Kathryn R. Wagner, Hoda Z. Abdel-Hamid, Cuixia Tian, Jean K. Mah, Francesco Muntoni, Michela Guglieri, Russell J. Butterfield, Lawrence Charnas, Shannon Marraffino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract We evaluated whether whole-body dual-energy X-ray absorptiometry (DXA) measures of lean body mass can be used as biomarkers for disease progression and treatment effects in patients with Duchenne muscular dystrophy. This post hoc analysis ut
Externí odkaz:
https://doaj.org/article/b1991b15576f4babafe571cf86344cff
Autor:
Sarah P. Sherlock, Jeffrey Palmer, Kathryn R. Wagner, Hoda Z. Abdel-Hamid, Enrico Bertini, Cuixia Tian, Jean K. Mah, Anna Kostera-Pruszczyk, Francesco Muntoni, Michela Guglieri, John F. Brandsema, Eugenio Mercuri, Russell J. Butterfield, Craig M. McDonald, Lawrence Charnas, Shannon Marraffino
Publikováno v:
Journal of Neurology. 269:4421-4435
Duchenne muscular dystrophy (DMD) is a progressive, neuromuscular disorder caused by mutations in the DMD gene that results in a lack of functional dystrophin protein. Herein, we report the use of quantitative magnetic resonance imaging (MRI) measure
Autor:
Arun J. Sanyal, Sudha S. Shankar, Roberto A. Calle, Anthony E. Samir, Claude B. Sirlin, Sarah P. Sherlock, Rohit Loomba, Kathryn J. Fowler, Clayton A. Dehn, Helen Heymann, Tania N. Kamphaus
Publikováno v:
Nat Med
Autor:
Eugenio Mercuri, Jean K. Mah, C. Tian, Hoda Abdel-Hamid, Craig M. McDonald, Craig Campbell, J. Statland, Michael Binks, Alesia Sadosky, Lawrence Charnas, Jeffrey P. Palmer, Michela Guglieri, Brenda L. Wong, Francesco Muntoni, Yasuhiro Takeshima, Kathryn R. Wagner, Sarah P. Sherlock, Shannon Marraffino, Anna Kostera-Pruszczyk, Enrico Bertini, Peter I. Karachunski, Russell J. Butterfield, Vivek S. Purohit, Chiara Fiorillo
Publikováno v:
Paediatrics Publications
We report results from a phase 2, randomized, double-blind, 2-period trial (48 weeks each) of domagrozumab and its open-label extension in patients with Duchenne muscular dystrophy (DMD). Of 120 ambulatory boys (aged 6 to years) with DMD, 80 were tre
Autor:
Sarah P, Sherlock, Jeffrey, Palmer, Kathryn R, Wagner, Hoda Z, Abdel-Hamid, Enrico, Bertini, Cuixia, Tian, Jean K, Mah, Anna, Kostera-Pruszczyk, Francesco, Muntoni, Michela, Guglieri, John F, Brandsema, Eugenio, Mercuri, Russell J, Butterfield, Craig M, McDonald, Lawrence, Charnas, Shannon, Marraffino
Publikováno v:
Journal of neurology. 269(8)
Duchenne muscular dystrophy (DMD) is a progressive, neuromuscular disorder caused by mutations in the DMD gene that results in a lack of functional dystrophin protein. Herein, we report the use of quantitative magnetic resonance imaging (MRI) measure
Autor:
Ali Guermazi, Frank W. Roemer, Andrew J. Kompel, Luis E. Diaz, Michel D. Crema, Mark T. Brown, Anne Hickman, Glenn C. Pixton, Lars Viktrup, Robert J. Fountaine, Aimee Burr, Sarah P. Sherlock, Christine R. West
Publikováno v:
Osteoarthritis Imaging. 2:100082
Publikováno v:
Biomarkers in Medicine
Aim: Using baseline data from a clinical trial of domagrozumab in Duchenne muscular dystrophy, we evaluated the correlation between functional measures and quantitative MRI assessments of thigh muscle. Patients & methods: Analysis included timed func
Autor:
Keith S. Kanik, David Li, Walter P. Maksymowych, Xenofon Baraliakos, Sarah P. Sherlock, Thijs Hendrikx, Dona Fleishaker, Désirée van der Heijde, Atul Deodhar
Publikováno v:
Rheumatology (Oxford, England)
Rheumatology, 57(8), 1390-1399
Rheumatology, 57(8), 1390-1399
Objectives Minimally important changes (MICs) for SPondyloArthritis Research Consortium of Canada (SPARCC) MRI scores are ⩾2.5 for SI joint and ⩾5 for spine. This post hoc analysis assessed achievement of MIC in SPARCC scores in biologic-naïve p